References
Chen, X., and Song, E. (2022). The theory of tumor ecosystem. Cancer Commun 42, 587–608.
Dong, W., Wu, X., Ma, S., Wang, Y., Nalin, A.P., Zhu, Z., Zhang, J., Benson, D.M., He, K., Caligiuri, M.A., et al. (2019). The mechanism of Anti—PD-Ll antibody efficacy against PD-Ll—Negative tumors identifies NK Cells expressing PD-L1 as a cytolytic effector. Cancer Discovery 9, 1422–1437.
Guo, X., and Dong, C. (2022). Zooming on T cells in cancer. Sci China Life Sci 65, 1466–1468.
Jiang, P., Gu, S., Pan, D., Fu, J., Sahu, A., Hu, X., Li, Z., Traugh, N., Bu, X., Li, B., et al. (2018). Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nat Med 24, 1550–1558.
Kim, R., Emi, M., and Tanabe, K. (2007). Cancer immunoediting from immune surveillance to immune escape. Immunology 121, 1–14.
Mlecnik, B., Bifulco, C., Bindea, G., Marliot, F., Lugli, A., Lee, J.J., Zlobec, I., Rau, T.T., Berger, M.D., Nagtegaal, I.D., et al. (2020). Multicenter international society for immunotherapy of cancer study of the consensus immunoscore for the prediction of survival and response to chemotherapy in stage III colon cancer. J Clin Oncol 38, 3638–3651.
Seya, T., Begum, N.A., Nomura, M., Tsuji, S., Matsumoto, M., Hayashi, A., Azuma, I., and Toyoshima, K. (2000). Innate immune therapy for cancer. Screen for molecules capable of activating the innate immune system. Adv Exp Med Biol 465, 229–237.
Zhang, J., Huang, D., Saw, P.E., and Song, E. (2022). Turning cold tumors hot: from molecular mechanisms to clinical applications. Trends Immunol 43, 523–545.
Zhang, Y., and Zhang, Z. (2020). The history and advances in cancer immunotherapy: understanding the characteristics of tumor-infiltrating immune cells and their therapeutic implications. Cell Mol Immunol 17, 807–821.
Zhao, Z., Xiao, X., Saw, P.E., Wu, W., Huang, H., Chen, J., and Nie, Y. (2020). Chimeric antigen receptor T cells in solid tumors: a war against the tumor microenvironment. Sci China Life Sci 63, 180–205.
Acknowledgements
This work was supported by grants from the National Key Research and Development Program of China (2021YFA1300502), the Natural Science Foundation of China (92057210, 82125017, 91942309).
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Su, S. Effector Immune Cell Deployment: a revolutionized concept in cancer immunotherapy. Sci. China Life Sci. 66, 1930–1933 (2023). https://doi.org/10.1007/s11427-022-2184-6
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DOI: https://doi.org/10.1007/s11427-022-2184-6