Article PDF
Avoid common mistakes on your manuscript.
References
Badu, K., Oyebola, K., Zahouli, J.Z.B., Fagbamigbe, A.F., de Souza, D.K., Dukhi, N., Amankwaa, E.F., Tolba, M.F., Sylverken, A.A., Mosi, L., et al. (2021). SARS-COV-2 viral shedding and transmission dynamics: Implications of WHO COVID-19 discharge guidelines. Front Med 8, 648660.
Bok, K., Sitar, S., Graham, B.S., and Mascola, J.R. (2021). Accelerated COVID-19 vaccine development: Milestones, lessons, and prospects. Immunity 54, 1636–1651.
Bongiovanni, M., Bini, F., Giuliani, G., and Gianturco, L. (2021). Insight into the reason of prolonged viral rna shedding in patients with COVID-19 infection. J Infect 82, e13–e14.
Cevik, M., Tate, M., Lloyd, O., Maraolo, A.E., Schafers, J., and Ho, A. (2021). SARS-COV-2, SARS-COV, and MERS-COV viral load dynamics, duration of viral shedding, and infectiousness: A systematic review and meta-analysis. Lancet Microbe 2, e13–e22.
Lu, L., Zhang, H., Zhan, M., Jiang, J., Yin, H., Dauphars, D.J., Li, S.Y., Li, Y., and He, Y.W. (2020). Antibody response and therapy in COVID-19 patients: what can be learned for vaccine development? Sci China Life Sci 63, 1833–1849.
Iyer, A.S., Jones, F.K., Nodoushani, A., Kelly, M., Becker, M., Slater, D., Mills, R., Teng, E., Kamruzzaman, M., Garcia-Beltran, W.F., et al. (2020). Persistence and decay of human antibody responses to the receptor binding domain of SARS-CoV-2 spike protein in COVID-19 patients. Sci Immunol 5.
Sadarangani, M., Marchant, A., and Kollmann, T.R. (2021). Immunological mechanisms of vaccine-induced protection against COVID-19 in humans. Nat Rev Immunol 21, 475–484.
Zhang, N., Gong, Y., Meng, F., Shi, Y., Wang, J., Mao, P., Chuai, X., Bi, Y., Yang, P., and Wang, F. (2021). Comparative study on virus shedding patterns in nasopharyngeal and fecal specimens of COVID-19 patients. Sci China Life Sci 64, 486–488.
Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., Xiang, J., Wang, Y., Song, B., Gu, X., et al. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in wuhan, china: A retrospective cohort study. Lancet 395, 1054–1062.
Acknowledgements
This work was supported by the National Natural Science Foundation of China (82073673), the National Science and Technology Major Project of China (2018ZX10715002-004-002, 2018ZX10713001-001), the Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD), Key Research and Development Program of Department of Health of Jiangsu (ZDB2020036), and Project of Nanjing Infectious Disease Clinical Medical Center Construction (NA2021062071).
Author information
Authors and Affiliations
Corresponding authors
Additional information
Compliance and ethics
The authors declare that they have no conflict of interest. This study was approved by the ethics committee of the Second Hospital of Nanjing (2020-LS-ky003). Written informed consent was waived by the Ethics Commission.
Rights and permissions
About this article
Cite this article
Hu, Z., Yin, Y., Wang, K. et al. Impact of inactivated COVID-19 vaccines on viral shedding in B.1.617.2 (Delta) variant-infected patients. Sci. China Life Sci. 65, 2556–2559 (2022). https://doi.org/10.1007/s11427-021-2115-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11427-021-2115-7