Skip to main content
SpringerLink
Log in

NTP4 modulates miRNA accumulation via asymmetric modification of miRNA/miRNA* duplex

  • Letter to the Editor
  • Published:
Science China Life Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Mi, S., Cai, T., Hu, Y., Chen, Y., Hodges, E., Ni, F., Wu, L., Li, S., Zhou, H., Long, C., et al. (2008). Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5’ terminal nucleotide. Cell 133, 116–127.

    Article  CAS  Google Scholar 

  • Ren, G., Chen, X., and Yu, B. (2012). Uridylation of miRNAs by hen1 suppressor1 in Arabidopsis. Curr Biol 22, 695–700.

    Article  CAS  Google Scholar 

  • Song, J., Wang, X., Song, B., Gao, L., Mo, X., Yue, L., Yang, H., Lu, J., Ren, G., Mo, B., et al. (2019). Prevalent cytidylation and uridylation of precursor miRNAs in Arabidopsis. Nat Plants 5, 1260–1272.

    Article  CAS  Google Scholar 

  • Tu, B., Liu, L., Xu, C., Zhai, J., Li, S., Lopez, M.A., Zhao, Y., Yu, Y., Ramachandran, V., Ren, G., et al. (2015). Distinct and cooperative activities of HESO1 and URT1 nucleotidyl transferases in microRNA turnover in Arabidopsis. PLoS Genet 11, e1005119.

    Article  Google Scholar 

  • Wang, J., Mei, J., and Ren, G. (2019). Plant microRNAs: Biogenesis, homeostasis, and degradation. Front Plant Sci 10, 360.

    Article  Google Scholar 

  • Wang, X., Zhang, S., Dou, Y., Zhang, C., Chen, X., Yu, B., and Ren, G. (2015). Synergistic and independent actions of multiple terminal nucleotidyl transferases in the 3’ tailing of small RNAs in Arabidopsis. PLoS Genet 11, e1005091.

    Article  Google Scholar 

  • Yu, B., Yang, Z., Li, J., Minakhina, S., Yang, M., Padgett, R.W., Steward, R., and Chen, X. (2005). Methylation as a crucial step in plant microRNA biogenesis. Science 307, 932–935.

    Article  CAS  Google Scholar 

  • Zhao, Y., Yu, Y., Zhai, J., Ramachandran, V., Dinh, T.T., Meyers, B.C., Mo, B., and Chen, X. (2012). The Arabidopsis nucleotidyl transferase HESO1 uridylates unmethylated small RNAs to trigger their degradation. Curr Biol 22, 689–694.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the National Natural Science Foundation of China (31900396, 31870287, 31801078), Natural Science Foundation of Guangdong Province (2018A030313966) and China Postdoctoral Science Foundation (2019M653011). We thank Dr. Guodong Ren for technical support.

Author information

Author notes

  1. Contributed equally to this work

Authors and Affiliations

  1. Guangdong Provincial Key Laboratory for Plant Epigenetics, Longhua Institute of Innovative Biotechnology, College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, 518060, China

    Wenwen Kong, Yongbing Ren, Xintong Xu, Beixin Mo, Yu Yu & Xiaoyan Wang

  2. Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, China

    Wenwen Kong & Yongbing Ren

  3. Advanced Institute of Natural Sciences, Beijing Normal University at Zhuhai, Zhuhai, 519087, China

    Xianxin Dong

  4. State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, 200438, China

    Yuan Wang

Authors
  1. Wenwen Kong
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xianxin Dong
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yongbing Ren
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yuan Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Xintong Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Beixin Mo
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Yu Yu
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Xiaoyan Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Yu Yu or Xiaoyan Wang.

Additional information

Compliance and ethics

The author(s) declare that they have no conflict of interest.

Supporting Information

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kong, W., Dong, X., Ren, Y. et al. NTP4 modulates miRNA accumulation via asymmetric modification of miRNA/miRNA* duplex. Sci. China Life Sci. 64, 832–835 (2021). https://doi.org/10.1007/s11427-020-1803-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11427-020-1803-9

Search

Navigation