Biological data processing based on bio-processor unit (BPU), a new concept for next generation computational biology



  1. Alser, M., Hassan, H., Xin, H., Ergin, O., Mutlu, O., and Alkan, C. (2017). GateKeeper: a new hardware architecture for accelerating pre-alignment in DNA short read mapping. Bioinformatics 33, 3355–3363.CrossRefPubMedGoogle Scholar
  2. Benson, D.A., Cavanaugh, M., Clark, K., Karsch-Mizrachi, I., Ostell, J., Pruitt, K.D., and Sayers, E.W. (2018). GenBank. Nucleic Acids Res 46, D41–D47.CrossRefPubMedGoogle Scholar
  3. Hu, Y., and Georgiou, P. (2016). A real-time de novo DNA sequencing assembly platform based on an FPGA implementation. IEEE/ACM Trans Comput Biol Bioinf 13, 291–300.CrossRefGoogle Scholar
  4. NCBI Resource Coordinators. (2018). Database resources of the National Center for Biotechnology Information. Nucleic Acids Res 46, D8–D13.Google Scholar
  5. Stephens, Z.D., Lee, S.Y., Faghri, F., Campbell, R.H., Zhai, C., Efron, M.J., Iyer, R., Schatz, M.C., Sinha, S., and Robinson, G.E. (2015). Big data: astronomical or genomical? PLoS Biol 13, e1002195.CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Di Liu
    • 1
  • Dongbo Bu
    • 2
  • Tieliu Shi
    • 3
  • Jianxiao Quan
    • 4
    • 5
  • Depeng Wang
    • 6
  • Yongyong Shi
    • 7
  • Xiao-Chen Bo
    • 8
  • Wenbao Han
    • 4
  1. 1.Computational Virology Group, Wuhan Institute of VirologyChinese Academy of SciencesWuhanChina
  2. 2.Key Laboratory of Intelligent Information Processing, Institute of Computing TechnologyChinese Academy of SciencesBeijingChina
  3. 3.Center for Bioinformatics and Computational Biology, and the Institute of Biomedical Sciences, School of Life SciencesEast China Normal UniversityShanghaiChina
  4. 4.State Key Laboratory of Mathematical Engineering and Advanced ComputationWuxiChina
  5. 5.Jiangsu Variable Supercomputer Tech Co, Ltd.WuxiChina
  6. 6.NextOmics BiosciencesWuhanChina
  7. 7.Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education)Shanghai Jiao Tong UniversityShanghaiChina
  8. 8.Beijing Institute of Radiation MedicineBeijingChina

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