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N-terminal domain of the RNA polymerase of very virulent infectious bursal disease virus contributes to viral replication and virulence

  • Li Gao
  • Kai Li
  • Xiaole Qi
  • Yulong Gao
  • Yongqiang Wang
  • Honglei Gao
  • Xiaomei Wang
Letter to the Editor

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Notes

Acknowledgements

This work was supported by the National Natural Science Foundation of China (31500129, 31430087).

Supplementary material

11427_2017_9297_MOESM1_ESM.docx (1.2 mb)
Supplementary material, approximately 1241 KB.

References

  1. Boot, H.J., ter Huurne, A.A.H.M., Hoekman, A.J.W., Peeters, B.P.H., and Gielkens, A.L.J. (2000). Rescue of very virulent and mosaic infectious bursal disease virus from cloned cDNA: VP2 is not the sole determinant of the very virulent phenotype. J Virol 74, 6701–6711.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Brandt, M., Yao, K., Liu, M., Heckert, R.A., and Vakharia, V.N. (2001). Molecular determinants of virulence, cell tropism, and pathogenic phenotype of infectious bursal disease virus. J Virol 75, 11974–11982.CrossRefPubMedPubMedCentralGoogle Scholar
  3. Hon, C.C., Lam, T.Y., Drummond, A., Rambaut, A., Lee, Y.F., Yip, C.W., Zeng, F., Lam, P.Y., Ng, P.T.W., and Leung, F.C.C. (2006). Phylogenetic analysis reveals a correlation between the expansion of very virulent infectious bursal disease virus and reassortment of its genome segment B. J Virol 80, 8503–8509.CrossRefPubMedPubMedCentralGoogle Scholar
  4. Nouën, C.L., Toquin, D., Müller, H., Raue, R., Kean, K.M., Langlois, P., Cherbonnel, M., and Eterradossi, N. (2012). Different domains of the RNA polymerase of infectious bursal disease virus contribute to virulence. PLoS ONE 7, e28064.CrossRefPubMedPubMedCentralGoogle Scholar
  5. Pan, J., Vakharia, V.N., and Tao, Y.J. (2007). The structure of a birnavirus polymerase reveals a distinct active site topology. Proc Natl Acad Sci USA 104, 7385–7390.CrossRefPubMedPubMedCentralGoogle Scholar
  6. Berg, T.P. (2000). Acute infectious bursal disease in poultry: a review. Avian Pathol 29, 175–194.CrossRefPubMedGoogle Scholar
  7. von Einem, U.I., Gorbalenya, A.E., Schirrmeier, H., Behrens, S.E., Letzel, T., and Mundt, E. (2004). VP1 of infectious bursal disease virus is an RNA-dependent RNA polymerase. J General Virol 85, 2221–2229.CrossRefGoogle Scholar

Copyright information

© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2018

Authors and Affiliations

  • Li Gao
    • 1
  • Kai Li
    • 1
  • Xiaole Qi
    • 1
  • Yulong Gao
    • 1
  • Yongqiang Wang
    • 1
  • Honglei Gao
    • 1
  • Xiaomei Wang
    • 1
    • 2
  1. 1.Division of Avian Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institutethe Chinese Academy of Agricultural SciencesHarbinChina
  2. 2.Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Disease and ZoonosesYangzhouChina

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