Article PDF
Avoid common mistakes on your manuscript.
References
Clapham DE. Calcium signaling. Cell, 2007, 131: 1047–1058
Katz AK, Glusker JP, Beebe SA, Bock CW. Calcium ion coordination: a comparison with that of beryllium, magnesium, and zinc. J Am Chem Soc, 1996, 118: 5752–5763
Yuan P, Leonetti MD, Hsiung Y, MacKinnon R. Open structure of the Ca2+ gating ring in the high-conductance Ca2+-activated K+ channel. Nature, 2012, 481: 94–97
Song ZX, Chen Q, Ding Q, Zheng F, Li CW, Xu LP, Wang HB. Function of Ca2+-/calmodulin-dependent protein kinase IV in Ca2+-stimulated neuronal signaling and behavior. Sci China Life Sci, 2015, 58: 6–13
Zhang C, Miller CL, Brown EM, Yang JJ. The calcium sensing receptor: from calcium sensing to signaling. Sci China Life Sci, 2015, 58: 14–27
Buraei Z, Lumen E, Kaur S, Yang J. RGK regulation of voltage-gated calcium channels. Sci China Life Sci, 2015, 58: 28–38
Fu J, Gao ZB, Shen B, Zhu MX. Canonical transient receptor potential 4 and its small molecule modulators. Sci China Life Sci, 2015, 58: 39–47
Pan Z, Ma JJ. Open Sesame: treasure in store operated calcium entry pathway for cancer therapy. Sci China Life Sci, 2015, 58: 48–53
Zhao YT, Valdivia CR, Gurrola GB, Hernández JJ, Valdivia HH. Arrhythmogenic mechanisms in ryanodine receptor channelopathies. Sci China Life Sci, 2015, 58: 54–58
Nita LI, Hershfinkel M, Sekler I. Life after the birth of the mitochondrial Na+/Ca2+ exchanger, NCLX. Sci China Life Sci, 2015, 58: 59–65
Liao M, Cao E, Julius D, Cheng Y. Structure of the trpv1 ion channel determined by electron cryo-microscopy. Nature, 2013, 504: 107–112
Wang LG, Tonggu LG. Membrane protein reconstitution for functional and structural studies. Sci China Life Sci, 2015, 58: 66–74
Author information
Authors and Affiliations
Corresponding authors
Additional information
This article is published with open access at link.springer.com
Biographical Sketch
Dr. Zheng Jie is a Professor in School of Medicine at the University of California at Davis, USA, where he serves as a faculty member in the Department of Physiology and Membrane Biology since 2004. He earned his bachelor’s degree in physiology and biophysics in 1988, and a master’s degree in biophysics in 1991 from Peking University, Beijing, China. He earned his Ph.D. in physiology in 1998 from Yale, where he studied with Dr. Fredrick J. Sigworth on patch-clamp recording, singlechannel analysis, and voltage-dependent channel activation mechanism. He received his postdoctoral training at Howard Hughes Medical Institute and the University of Washington during 1999–2003, working with Dr. William N. Zagotta on the cyclic nucleotide-gated channels activation mechanism and novel ion channel fluorescence techniques. Currently, his research focuses on the activation mechanism of the temperature-sensitive TRP channels.
Dr. Zeng XuHui is a “Jing-Gang Scholar” Professor in Nanchang University and a selected winner of the “Gan-Po 555 Excellence Project” in Jiangxi Province. He finished his postdoctoral training in Washington University in St. Louis, School of Medicine, and served as a Research Instructor there before joining the Institute of Life Science in Nanchang University in 2011. Dr. Zeng has devoted his research efforts on understanding the general biophysical properties of ion channels together with the underlying mechanisms by which the ion channels would be regulated. At present, Dr. Zeng focuses on investigating the components, the physiological functions and the clinical relevance of ion channels in matured mammalian sperm. Dr. Zeng has contributed significantly to a series of research work published on prestigious peer-reviewed journals, such as Nature, Nature Structural Biology, Proceedings of the National Academy of Sciences, Journal of Neuroscience, Journal of General Physiology. Dr. Zeng is currently responsible for several research projects financially supported by the National Natural Science Foundation or Ministry of Science and Technology of China.
Rights and permissions
Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Zheng, J., Zeng, X. & Wang, S. Calcium ion as cellular messenger. Sci. China Life Sci. 58, 1–5 (2015). https://doi.org/10.1007/s11427-014-4795-y
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11427-014-4795-y