References
Towner JS, Sealy TK, Khristova ML, Albariño CG, Conlan S, Reeder SA, Quan PL, Lipkin WI, Downing R, Tappero JW, Okware S, Lutwama J, Bakamutumaho B, Kayiwa J, Comer JA, Rollin PE, Ksiazek TG, Nichol ST. Newly discovered Ebola virus associated with hemorrhagic fever outbreak in Uganda. PLoS Pathog, 2008, 4: e100212
Smith LM, Hensley LE, Geisbert TW, Johnson J, Stossel A, Honko A, Yen JY, Geisbert J, Paragas J, Fritz E, Olinger G, Young HA, Rubins KH, Karp CL. Interferon-ß therapy prolongs survival in rhesus macaque models of Ebola and Marburg hemorrhagic fever. J Infect Dis, 2013, 208: 310–318
Sullivan NJ, Sanchez A, Rollin PE, Yang ZY, Nabel GJ. Development of a preventive vaccine for Ebola virus infection in primates. Nature, 2000, 408: 605–609
Elshabrawy HA, Fan J, Haddad CS, Ratia K, Broder CC, Caffrey M, Prabhakar BS. Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assay. J Virol, 2014, 88: 4353e65
Mahanty S, Bray M. Pathogenesis of filoviral haemorrhagic fevers. Lancet Infect Dis, 2004, 4: 487–498
Xie J, Jiao Y, Qiu ZF, Li Q, Li TS. Significant elevation of B cells at acute stage in enterovirus 71-infected children with central nervous system involvement. Scand J Infect Dis, 2010, 42: 931–935
Mori I, Parizot C, Dorgham K, Demeret S, Amoura Z, Bolgert F, Gorochov G. Prominent plasmacytosis following intravenous immunoglobulin correlates with clinical improvement in Guillain-barre syndrome. PLoS One, 2008, 3: e2109–2118
Sundblad A, Marcos MA, Malanchere E, Castro A, Haury M, Huetz F, Nobrega A, Freitas A, Coutinho A. Observations on the mode of action of normal immunoglobulin at high doses. Immunol Rev, 1994, 139: 125–158
Makhoul B, Braun E, Herskovitz M, Ramadan R, Hadad S, Norberto K. Hyperimmune gammaglobulin for the treatment of West Nile virus encephalitis. Isr Med Assoc J, 2009, 11: 151–153
Shen X, Tomaras GD. Alterations of the B-cell response by HIV-1 replication. Curr HIV/aids Rep, 2011, 8: 23–30
Author information
Authors and Affiliations
Corresponding author
Additional information
This article is published with open access at link.springer.com
Rights and permissions
Open Access This article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Ge, Y., Li, T. May early intervention with intravenous immunoglobulin pose a potentially successful treatment for Ebola virus infection?. Sci. China Life Sci. 58, 108–110 (2015). https://doi.org/10.1007/s11427-014-4794-z
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11427-014-4794-z
Keywords
- Severe Acute Respiratory Syndrome
- Capillary Leak Syndrome
- Central Nervous System Complication
- Severe Acute Respiratory Syndrome Coronavirus
- Convalescent Plasma