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The molecular mechanism of embryonic stem cell pluripotency and self-renewal

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Abstract

The self-renewal and pluripotency of embryonic stem cells (ESCs) is regulated by a network, which consists of a series of cell factors in microenviroments, a chain of transcription factors and certain signal conduction pathways. This article reviews recent progress in this field to elucidate the mechanism involved.

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Authors and Affiliations

  1. Laboratory of Stem Cell Biology, Beijing Institution of Transfusion Medicine, Beijing, 100850, China

    Liu YuXiao, Ji Lei, Ten Yue, Wang YunFang & Pei XueTao

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  1. Liu YuXiao
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  2. Ji Lei
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  3. Ten Yue
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  4. Wang YunFang
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  5. Pei XueTao
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Corresponding author

Correspondence to Pei XueTao.

Additional information

Supported by the State 863 High Technology R&D Project of China (Grant No. 2006AA02A107) and the National Key Project for Basic Research of China (Grant No. 2005CB522702 to X. T. Pei)

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Liu, Y., Ji, L., Ten, Y. et al. The molecular mechanism of embryonic stem cell pluripotency and self-renewal. SCI CHINA SER C 50, 619–623 (2007). https://doi.org/10.1007/s11427-007-0074-5

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  • DOI: https://doi.org/10.1007/s11427-007-0074-5

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