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Emerging low-dimensional black phosphorus: from physical-optical properties to biomedical applications

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Abstract

Low-dimensional black phosphorus (BP) is a class of nanomaterial derived from layered semiconductor BP which has gained tremendous attention in a variety of fields, owing to its uncommon structural features and appealing physical properties. More surprisingly, it has addressed current biomedical obstacles due to its orthorhombic puckered honeycomb crystal structure and unique properties such as tunable direct-bandgap, high carrier mobility, and exceptional photo-responsiveness. However, few reviews have focused on the interactions of low-dimensional BP’s physical properties with its biomedical performances. Herein, we discuss the physical properties of low-dimensional BP and potential biomedical applications associated with these physical properties. Moreover, different preparation methods, surface modification techniques, and future challenges, as well as future outlooks, are presented. This comprehensive review will provide a clear understanding of the relationship between low-dimensional BP’s physical properties and biomedical performances, with the ultimate goal of better knowledge of utilizing BP.

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References

  1. Kou L, Chen C, Smith SC. J Phys Chem Lett, 2015, 6: 2794–2805

    Article  CAS  Google Scholar 

  2. Chen P, Li N, Chen X, Ong WJ, Zhao X. 2D Mater, 2017, 5: 014002

    Article  Google Scholar 

  3. Li L, Yu Y, Ye GJ, Ge Q, Ou X, Wu H, Feng D, Chen XH, Zhang Y. Nat Nanotech, 2014, 9: 372–377

    Article  CAS  Google Scholar 

  4. Bagheri S, Mansouri N, Aghaie E. Int J Hydrogen Energy, 2016, 41: 4085–4095

    Article  CAS  Google Scholar 

  5. Anju S, Ashtami J, Mohanan PV. Mater Sci Eng-C, 2019, 97: 978–993

    Article  CAS  Google Scholar 

  6. Zhang M, Wu Q, Zhang F, Chen L, Jin X, Hu Y, Zheng Z, Zhang H. Adv Opt Mater, 2019, 7: 1800224

    Article  Google Scholar 

  7. Pei J, Yang J, Yildirim T, Zhang H, Lu Y. Adv Mater, 2019, 31: 1706945

    Article  Google Scholar 

  8. Qiao J, Kong X, Hu ZX, Yang F, Ji W. Nat Commun, 2014, 5: 4475

    Article  CAS  Google Scholar 

  9. Li Y, He Y, Cai Y, Chen S, Liu J, Chen Y, Yuanjiang X. Laser Phys Lett, 2018, 15: 025301

    Article  Google Scholar 

  10. Liu X, Wood JD, Chen KS, Cho EK, Hersam MC. J Phys Chem Lett, 2015, 6: 773–778

    Article  CAS  Google Scholar 

  11. Qin G, Zhang X, Yue SY, Qin Z, Wang H, Han Y, Hu M. Phys Rev B, 2016, 94: 165445

    Article  Google Scholar 

  12. Tran V, Soklaski R, Liang Y, Yang L. Phys Rev B, 2014, 89: 235319

    Article  Google Scholar 

  13. Wang X, Mao N, Luo W, Kitadai H, Ling X. J Phys Chem Lett, 2018, 9: 2830–2837

    Article  CAS  Google Scholar 

  14. Lee IH, Martin-Moreno L, Mohr DA, Khaliji K, Low T, Oh SH. ACS Photonics, 2018, 5: 2208–2216

    Article  CAS  Google Scholar 

  15. Ehlen N, Sanna A, Senkovskiy BV, Petaccia L, Fedorov AV, Profeta G, Grüneis A. Phys Rev B, 2018, 97: 045143

    Article  CAS  Google Scholar 

  16. Buscema M, Groenendijk DJ, Blanter SI, Steele GA, van der Zant HSJ, Castellanos-Gomez A. Nano Lett, 2014, 14: 3347–3352

    Article  CAS  Google Scholar 

  17. Hanlon D, Backes C, Doherty E, Cucinotta CS, Berner NC, Boland C, Lee K, Harvey A, Lynch P, Gholamvand Z, Zhang S, Wang K, Moynihan G, Pokle A, Ramasse QM, McEvoy N, Blau WJ, Wang J, Abellan G, Hauke F, Hirsch A, Sanvito S, O’Regan DD, Duesberg GS, Nicolosi V, Coleman JN. Nat Commun, 2015, 6: 8563

    Article  CAS  Google Scholar 

  18. Miao X, Zhang G, Wang F, Yan H, Ji M. Nano Lett, 2018, 18: 3053–3059

    Article  CAS  Google Scholar 

  19. Chen W, Li K, Wang Y, Feng X, Liao Z, Su Q, Lin X, He Z. J Phys Chem Lett, 2017, 8: 591–598

    Article  CAS  Google Scholar 

  20. Hu W, Lin L, Zhang R, Yang C, Yang J. J Am Chem Soc, 2017, 139: 15429–15436

    Article  CAS  Google Scholar 

  21. Yuan Z, Li J, Yang M, Fang Z, Jian J, Yu D, Chen X, Dai L. J Am Chem Soc, 2019, 141: 4972–4979

    Article  CAS  Google Scholar 

  22. Liu H, Su Y, Deng D, Song H, Lv Y. Anal Chem, 2019, 91: 9174–9180

    Article  CAS  Google Scholar 

  23. Tao W, Ji X, Xu X, Islam MA, Li Z, Chen S, Saw PE, Zhang H, Bharwani Z, Guo Z, Shi J, Farokhzad OC. Angew Chem Int Ed, 2017, 56: 11896–11900

    Article  CAS  Google Scholar 

  24. Qiu M, Ren WX, Jeong T, Won M, Park GY, Sang DK, Liu LP, Zhang H, Kim JS. Chem Soc Rev, 2018, 47: 5588–5601

    Article  CAS  Google Scholar 

  25. Qu G, Xia T, Zhou W, Zhang X, Zhang H, Hu L, Shi J, Yu XF, Jiang G. Chem Rev, 2020, 120: 2288–2346

    Article  CAS  Google Scholar 

  26. Tang Z, Kong N, Ouyang J, Feng C, Kim NY, Ji X, Wang C, Farokhzad OC, Zhang H, Tao W. Matter, 2020, 2: 297–322

    Article  CAS  Google Scholar 

  27. Ouyang J, Feng C, Zhang X, Kong N, Tao W. Acc Mater Res, 2021, 2: 489–500

    Article  CAS  Google Scholar 

  28. Ge X, Xia Z, Guo S. Adv Funct Mater, 2019, 29: 1900318

    Article  Google Scholar 

  29. Ouyang J, Rao S, Liu R, Wang L, Chen W, Tao W, Kong N. Adv Drug Deliver Rev, 2022, 185: 114268

    Article  CAS  Google Scholar 

  30. Ouyang J, Ji X, Zhang X, Feng C, Tang Z, Kong N, Xie A, Wang J, Sui X, Deng L, Liu Y, Kim JS, Cao Y, Tao W. Proc Natl Acad Sci USA, 2020, 117: 28667–28677

    Article  CAS  Google Scholar 

  31. Chen W, Ouyang J, Liu H, Chen M, Zeng K, Sheng J, Liu Z, Han Y, Wang L, Li J, Deng L, Liu YN, Guo S. Adv Mater, 2017, 29: 1603864

    Article  Google Scholar 

  32. Xie H, Shao J, Ma Y, Wang J, Huang H, Yang N, Wang H, Ruan C, Luo Y, Wang QQ, Chu PK, Yu XF. Biomaterials, 2018, 164: 11–21

    Article  CAS  Google Scholar 

  33. Xia F, Wang H, Jia Y. Nat Commun, 2014, 5: 4458

    Article  CAS  Google Scholar 

  34. Zhang L, Wang Y, Wang J, Wang Y, Chen A, Wang C, Mo W, Li Y, Yuan Q, Zhang Y. ACS Appl Mater Interfaces, 2019, 11: 300–310

    Article  CAS  Google Scholar 

  35. Tao W, Zhu X, Yu X, Zeng X, Xiao Q, Zhang X, Ji X, Wang X, Shi J, Zhang H, Mei L. Adv Mater, 2017, 29: 1603276

    Article  Google Scholar 

  36. Choi JR, Yong KW, Choi JY, Nilghaz A, Lin Y, Xu J, Lu X. Theranostics, 2018, 8: 1005–1026

    Article  CAS  Google Scholar 

  37. Wang H, Yu XF. Small, 2018, 14: 1702830

    Article  Google Scholar 

  38. Islam A, van den Akker A, Feng PXL. Nano Lett, 2018, 18: 7683–7691

    Article  CAS  Google Scholar 

  39. Nicotra G, van Veen E, Deretzis I, Wang L, Hu J, Mao Z, Fabio V, Spinella C, Chiarello G, Rudenko A, Yuan S, Politano A. Nanoscale, 2018, 10: 21918–21927

    Article  CAS  Google Scholar 

  40. Pradhan NR, Garcia C, Lucking MC, Pakhira S, Martinez J, Rosenmann D, Divan R, Sumant AV, Terrones H, Mendoza-Cortes JL, McGill SA, Zhigadlo ND, Balicas L. Nanoscale, 2019, 11: 18449–18463

    Article  CAS  Google Scholar 

  41. Shao J, Ruan C, Xie H, Li Z, Wang H, Chu PK, Yu XF. Adv Sci, 2018, 5: 1700848

    Article  Google Scholar 

  42. Guo T, Wu Y, Lin Y, Xu X, Lian H, Huang G, Liu JZ, Wu X, Yang HH. Small, 2018, 14: 1702815

    Article  Google Scholar 

  43. Ouyang J, Xie A, Zhou J, Liu R, Wang L, Liu H, Kong N, Tao W. Chem Soc Rev, 2022, 51: 4996–5041

    Article  CAS  Google Scholar 

  44. Zong S, Wang L, Yang Z, Wang H, Wang Z, Cui Y. ACS Appl Mater Interfaces, 2019, 11: 5896–5902

    Article  CAS  Google Scholar 

  45. Yang D, Yang G, Yang P, Lv R, Gai S, Li C, He F, Lin J. Adv Funct Mater, 2017, 27: 1700371

    Article  Google Scholar 

  46. Li Z, Hu Y, Fu Q, Liu Y, Wang J, Song J, Yang H. Adv Funct Mater, 2019, 30: 1905758

    Article  Google Scholar 

  47. Chan L, Gao P, Zhou W, Mei C, Huang Y, Yu XF, Chu PK, Chen T. ACS Nano, 2018, 12: 12401–12415

    Article  CAS  Google Scholar 

  48. Shao J, Xie H, Huang H, Li Z, Sun Z, Xu Y, Xiao Q, Yu XF, Zhao Y, Zhang H, Wang H, Chu PK. Nat Commun, 2016, 7: 12967

    Article  CAS  Google Scholar 

  49. Passaglia E, Cicogna F, Costantino F, Coiai S, Legnaioli S, Lorenzetti G, Borsacchi S, Geppi M, Telesio F, Heun S, Ienco A, Serrano-Ruiz M, Peruzzini M. Chem Mater, 2018, 30: 2036–2048

    Article  CAS  Google Scholar 

  50. Ran J, Guo W, Wang H, Zhu B, Yu J, Qiao SZ. Adv Mater, 2018, 30: 1800128

    Article  Google Scholar 

  51. An CJ, Kang YH, Lee C, Cho SY. Adv Funct Mater, 2018, 28: 1800532

    Article  Google Scholar 

  52. Zheng Y, Yu Z, Ou H, Asiri AM, Chen Y, Wang X. Adv Funct Mater, 2018, 28: 1705407

    Article  Google Scholar 

  53. Yasaei P, Kumar B, Foroozan T, Wang C, Asadi M, Tuschel D, Indacochea JE, Klie RF, Salehi-Khojin A. Adv Mater, 2015, 27: 1887–1892

    Article  CAS  Google Scholar 

  54. Qiu S, Zou B, Sheng H, Guo W, Wang J, Zhao Y, Wang W, Yuen RKK, Kan Y, Hu Y. ACS Appl Mater Interfaces, 2019, 11: 13652–13664

    Article  CAS  Google Scholar 

  55. Xu Y, Wang Z, Guo Z, Huang H, Xiao Q, Zhang H, Yu XF. Adv Opt Mater, 2016, 4: 1223–1229

    Article  CAS  Google Scholar 

  56. Ryder CR, Wood JD, Wells SA, Yang Y, Jariwala D, Marks TJ, Schatz GC, Hersam MC. Nat Chem, 2016, 8: 597–602

    Article  CAS  Google Scholar 

  57. Gusmão R, Sofer Z, Pumera M. ACS Nano, 2018, 12: 5666–5673

    Article  Google Scholar 

  58. Bolognesi M, Moschetto S, Trapani M, Prescimone F, Ferroni C, Manca G, Ienco A, Borsacchi S, Caporali M, Muccini M, Peruzzini M, Serrano-Ruiz M, Calucci L, Castriciano MA, Toffanin S. ACS Appl Mater Interfaces, 2019, 11: 22637–22647

    Article  CAS  Google Scholar 

  59. Zeng X, Luo M, Liu G, Wang X, Tao W, Lin Y, Ji X, Nie L, Mei L. Adv Sci, 2018, 5: 1800510

    Article  Google Scholar 

  60. Zhou Q, Li Q, Yuan S, Chen Q, Wang J. Phys Chem Chem Phys, 2017, 19: 29232–29236

    Article  CAS  Google Scholar 

  61. Venuthurumilli PK, Ye PD, Xu X. ACS Nano, 2018, 12: 4861–4867

    Article  CAS  Google Scholar 

  62. Wang H, Zhang X, Xie Y. ACS Nano, 2018, 12: 9648–9653

    Article  CAS  Google Scholar 

  63. Lin J, Liang L, Ling X, Zhang S, Mao N, Zhang N, Sumpter BG, Meunier V, Tong L, Zhang J. J Am Chem Soc, 2015, 137: 15511–15517

    Article  CAS  Google Scholar 

  64. Zhu L, Zhang G, Li B. Phys Rev B, 2014, 90: 214302

    Article  Google Scholar 

  65. Favron A, Goudreault FA, Gosselin V, Groulx J, Côté M, Leonelli R, Germain JF, Phaneuf-L’Heureux AL, Francoeur S, Martel R. Nano Lett, 2018, 18: 1018–1027

    Article  CAS  Google Scholar 

  66. Liu Y, Liu Q, Zhang A, Cai J, Cao X, Li Z, Asimow PD, Zhou C. ACS Nano, 2018, 12: 8323–8329

    Article  CAS  Google Scholar 

  67. Sun Z, Xie H, Tang S, Yu XF, Guo Z, Shao J, Zhang H, Huang H, Wang H, Chu PK. Angew Chem Int Ed, 2015, 54: 11526–11530

    Article  CAS  Google Scholar 

  68. Tian B, Tian B, Smith B, Scott MC, Lei Q, Hua R, Tian Y, Liu Y. Proc Natl Acad Sci USA, 2018, 115: 4345–4350

    Article  CAS  Google Scholar 

  69. Wu X, Xu Y, Hu Y, Wu G, Cheng H, Yu Q, Zhang K, Chen W, Chen S. Nat Commun, 2018, 9: 4573

    Article  Google Scholar 

  70. Wang Z, Shen Y, Ito Y, Zhang Y, Du J, Fujita T, Hirata A, Tang Z, Chen M. ACS Nano, 2018, 12: 1571–1579

    Article  CAS  Google Scholar 

  71. Park BJ, Choi JS, Eom JH, Ha H, Kim HY, Lee S, Shin H, Yoon SG. ACS Nano, 2018, 12: 2008–2016

    Article  CAS  Google Scholar 

  72. Smith JB, Hagaman D, Ji HF. Nanotechnology, 2016, 27: 215602

    Article  Google Scholar 

  73. Li X, Deng B, Wang X, Chen S, Vaisman M, Karato S, Pan G, Larry Lee M, Cha J, Wang H, Xia F. 2D Mater, 2015, 2: 031002

    Article  Google Scholar 

  74. Zhang Y, Rui X, Tang Y, Liu Y, Wei J, Chen S, Leow WR, Li W, Liu Y, Deng J, Ma B, Yan Q, Chen X. Adv Energy Mater, 2016, 6: 1502409

    Article  Google Scholar 

  75. Yang Z, Hao J, Yuan S, Lin S, Yau HM, Dai J, Lau SP. Adv Mater, 2015, 27: 3748–3754

    Article  CAS  Google Scholar 

  76. Xiong S, Chen X, Liu Y, Fan T, Wang Q, Zhang H, Chen T. J Innov Opt Health Sci, 2020, 13: 2030008

    Article  CAS  Google Scholar 

  77. Sultana N, Degg A, Upadhyaya S, Nilges T, Sen Sarma N. Mater Adv, 2022, 3: 5557–5574

    Article  CAS  Google Scholar 

  78. Vishnoi P, Mazumder M, Barua M, Pati SK, Rao CNR. Chem Phys Lett, 2018, 699: 223–228

    Article  CAS  Google Scholar 

  79. Gui R, Jin H, Wang Z, Li J. Chem Soc Rev, 2018, 47: 6795–6823

    Article  CAS  Google Scholar 

  80. Zhang X, Xie H, Liu Z, Tan C, Luo Z, Li H, Lin J, Sun L, Chen W, Xu Z, Xie L, Huang W, Zhang H. Angew Chem Int Ed, 2015, 54: 3653–3657

    Article  CAS  Google Scholar 

  81. Guan L, Xing B, Niu X, Wang D, Yu Y, Zhang S, Yan X, Wang Y, Sha J. Chem Commun, 2018, 54: 595–598

    Article  CAS  Google Scholar 

  82. Pei J, Gai X, Yang J, Wang X, Yu Z, Choi DY, Luther-Davies B, Lu Y. Nat Commun, 2016, 7: 10450

    Article  CAS  Google Scholar 

  83. Wang H, Yang X, Shao W, Chen S, Xie J, Zhang X, Wang J, Xie Y. J Am Chem Soc, 2015, 137: 11376–11382

    Article  CAS  Google Scholar 

  84. Gnopo YMD, Watkins HC, Stevenson TC, DeLisa MP, Putnam D. Adv Drug Deliver Rev, 2017, 114: 132–142

    Article  CAS  Google Scholar 

  85. Ambrosi A, Sofer Z, Pumera M. Angew Chem Int Ed, 2017, 56: 10443–10445

    Article  CAS  Google Scholar 

  86. Li J, Chen C, Liu S, Lu J, Goh WP, Fang H, Qiu Z, Tian B, Chen Z, Yao C, Liu W, Yan H, Yu Y, Wang D, Wang Y, Lin M, Su C, Lu J. Chem Mater, 2018, 30: 2742–2749

    Article  CAS  Google Scholar 

  87. Yang S, Zhang K, Ricciardulli AG, Zhang P, Liao Z, Lohe MR, Zschech E, Blom PWM, Pisula W, Müllen K, Feng X. Angew Chem Int Ed, 2018, 57: 4677–4681

    Article  CAS  Google Scholar 

  88. Ou W, Byeon JH, Thapa RK, Ku SK, Yong CS, Kim JO. ACS Nano, 2018, 12: 10061–10074

    Article  CAS  Google Scholar 

  89. Luo M, Fan T, Zhou Y, Zhang H, Mei L. Adv Funct Mater, 2019, 29: 1808306

    Article  Google Scholar 

  90. Gong X, Guan L, Li Q, Li Y, Zhang T, Pan H, Sun Q, Shen Y, Grätzel C, Zakeeruddin SM, Grätzel M, Wang M. Sci Adv, 2020, 6: eaay5661

    Article  CAS  Google Scholar 

  91. Ouyang J, Deng L, Chen W, Sheng J, Liu Z, Wang L, Liu YN. Chem Commun, 2018, 54: 2874–2877

    Article  CAS  Google Scholar 

  92. Liu G, Tsai HI, Zeng X, Qi J, Luo M, Wang X, Mei L, Deng W. Chem Eng J, 2019, 375: 121917

    Article  CAS  Google Scholar 

  93. Abellán G, Wild S, Lloret V, Scheuschner N, Gillen R, Mundloch U, Maultzsch J, Varela M, Hauke F, Hirsch A. J Am Chem Soc, 2017, 139: 10432–10440

    Article  Google Scholar 

  94. Zhang T, Wan Y, Xie H, Mu Y, Du P, Wang D, Wu X, Ji H, Wan L. J Am Chem Soc, 2018, 140: 7561–7567

    Article  CAS  Google Scholar 

  95. Guo X, Zhang W, Zhang J, Zhou D, Tang X, Xu X, Li B, Liu H, Wang G. ACS Nano, 2020, 14: 3651–3659

    Article  CAS  Google Scholar 

  96. Liu X, Qu D, Li HM, Moon I, Ahmed F, Kim C, Lee M, Choi Y, Cho JH, Hone JC, Yoo WJ. ACS Nano, 2017, 11: 9143–9150

    Article  CAS  Google Scholar 

  97. Yang Z, Hao J. Small Methods, 2018, 2: 1700296

    Article  Google Scholar 

  98. Zhao S, Wu J, Jin K, Ding H, Li T, Wu C, Pan N, Wang X. Adv Funct Mater, 2018, 28: 1802011

    Article  Google Scholar 

  99. Wu Q, Chen G, Gong K, Wang J, Ge X, Liu X, Guo S, Wang F. Matter, 2019, 1: 496–512

    Article  Google Scholar 

  100. Zhu M, Sun Z, Fujitsuka M, Majima T. Angew Chem Int Ed, 2018, 57: 2160–2164

    Article  CAS  Google Scholar 

  101. Feng R, Lei W, Sui X, Liu X, Qi X, Tang K, Liu G, Liu M. Appl Catal B-Environ, 2018, 238: 444–453

    Article  CAS  Google Scholar 

  102. Hu Z, Li Q, Lei B, Wu J, Zhou Q, Gu C, Wen X, Wang J, Liu Y, Li S, Zheng Y, Lu J, He J, Wang L, Xiong Q, Wang J, Chen W. Adv Mater, 2018, 30: 1801931

    Article  Google Scholar 

  103. Zhu M, Kim S, Mao L, Fujitsuka M, Zhang J, Wang X, Majima T. J Am Chem Soc, 2017, 139: 13234–13242

    Article  CAS  Google Scholar 

  104. Song J, Yang X, Jacobson O, Huang P, Sun X, Lin L, Yan X, Niu G, Ma Q, Chen X. Adv Mater, 2015, 27: 4910–4917

    Article  CAS  Google Scholar 

  105. Song J, Yang X, Yang Z, Lin L, Liu Y, Zhou Z, Shen Z, Yu G, Dai Y, Jacobson O, Munasinghe J, Yung B, Teng GJ, Chen X. ACS Nano, 2017, 11: 6102–6113

    Article  CAS  Google Scholar 

  106. Lv R, Yang D, Yang P, Xu J, He F, Gai S, Li C, Dai Y, Yang G, Lin J. Chem Mater, 2016, 28: 4724–4734

    Article  CAS  Google Scholar 

  107. Zhu M, Zhai C, Fujitsuka M, Majima T. Appl Catal B-Environ, 2018, 221: 645–651

    Article  CAS  Google Scholar 

  108. Wang C, Peng L, Qian Q, Du J, Wang S, Huang Y. Small, 2018, 14: 1703536

    Article  Google Scholar 

  109. Zhao Y, Zhou Q, Li Q, Yao X, Wang J. Adv Mater, 2017, 29: 1603990

    Article  Google Scholar 

  110. Guo Z, Chen S, Wang Z, Yang Z, Liu F, Xu Y, Wang J, Yi Y, Zhang H, Liao L, Chu PK, Yu XF. Adv Mater, 2017, 29: 1703811

    Article  Google Scholar 

  111. Zhao Y, Wang H, Huang H, Xiao Q, Xu Y, Guo Z, Xie H, Shao J, Sun Z, Han W, Yu XF, Li P, Chu PK. Angew Chem Int Ed, 2016, 55: 5003–5007

    Article  CAS  Google Scholar 

  112. Wood JD, Wells SA, Jariwala D, Chen KS, Cho EK, Sangwan VK, Liu X, Lauhon LJ, Marks TJ, Hersam MC. Nano Lett, 2014, 14: 6964–6970

    Article  CAS  Google Scholar 

  113. Sun Z, Zhao Y, Li Z, Cui H, Zhou Y, Li W, Tao W, Zhang H, Wang H, Chu PK, Yu XF. Small, 2017, 13: 1602896

    Article  Google Scholar 

  114. Wang J, Liu D, Huang H, Yang N, Yu B, Wen M, Wang X, Chu PK, Yu XF. Angew Chem Int Ed, 2018, 57: 2600–2604

    Article  CAS  Google Scholar 

  115. Abate Y, Akinwande D, Gamage S, Wang H, Snure M, Poudel N, Cronin SB. Adv Mater, 2018, 30: 1704749

    Article  Google Scholar 

  116. Cao Y, Tian X, Gu J, Liu B, Zhang B, Song S, Fan F, Chen Y. Angew Chem Int Ed, 2018, 57: 4543–4548

    Article  CAS  Google Scholar 

  117. Qu G, Liu W, Zhao Y, Gao J, Xia T, Shi J, Hu L, Zhou W, Gao J, Wang H, Luo Q, Zhou Q, Liu S, Yu XF, Jiang G. Angew Chem Int Ed, 2017, 56: 14488–14493

    Article  CAS  Google Scholar 

  118. Sofer Z, Luxa J, Bouša D, Sedmidubský D, Lazar P, Hartman T, Hardtdegen H, Pumera M. Angew Chem Int Ed, 2017, 56: 9891–9896

    Article  CAS  Google Scholar 

  119. Zhao Y, Tong L, Li Z, Yang N, Fu H, Wu L, Cui H, Zhou W, Wang J, Wang H, Chu PK, Yu XF. Chem Mater, 2017, 29: 7131–7139

    Article  CAS  Google Scholar 

  120. Xu Y, Ren F, Liu H, Zhang H, Han Y, Liu Z, Wang W, Sun Q, Zhao C, Li Z. ACS Appl Mater Interfaces, 2019, 11: 21399–21407

    Article  CAS  Google Scholar 

  121. Li Y, Du Z, Liu X, Ma M, Yu D, Lu Y, Ren J, Qu X. Small, 2019, 15: 1901116

    Article  Google Scholar 

  122. Wu L, Wang J, Lu J, Liu D, Yang N, Huang H, Chu PK, Yu XF. Small, 2018, 14: 1801405

    Article  Google Scholar 

  123. Tan L, Li J, Liu X, Cui Z, Yang X, Yeung KWK, Pan H, Zheng Y, Wang X, Wu S. Small, 2018, 14: 1703197

    Article  Google Scholar 

  124. Li Z, Guo T, Hu Y, Qiu Y, Liu Y, Wang H, Li Y, Chen X, Song J, Yang H. ACS Appl Mater Interfaces, 2019, 11: 9860–9871

    Article  CAS  Google Scholar 

  125. Geng S, Wu L, Cui H, Tan W, Chen T, Chu PK, Yu XF. Chem Commun, 2018, 54: 6060–6063

    Article  CAS  Google Scholar 

  126. Huang H, He L, Zhou W, Qu G, Wang J, Yang N, Gao J, Chen T, Chu PK, Yu XF. Biomaterials, 2018, 171: 12–22

    Article  CAS  Google Scholar 

  127. Song J, Cheng L, Liu A, Yin J, Kuang M, Duan H. J Am Chem Soc, 2011, 133: 10760–10763

    Article  CAS  Google Scholar 

  128. Wang Y, Hu X, Zhang L, Zhu C, Wang J, Li Y, Wang Y, Wang C, Zhang Y, Yuan Q. Nat Commun, 2019, 10: 2829

    Article  Google Scholar 

  129. Ye X, Liang X, Chen Q, Miao Q, Chen X, Zhang X, Mei L. ACS Nano, 2019, 13: 2956–2968

    Article  CAS  Google Scholar 

  130. Lee M, Park YH, Kang EB, Chae A, Choi Y, Jo S, Kim YJ, Park SJ, Min B, An TK, Lee J, In SI, Kim SY, Park SY, In I. ACS Omega, 2017, 2: 7096–7105

    Article  CAS  Google Scholar 

  131. Qiu M, Wang D, Liang W, Liu L, Zhang Y, Chen X, Sang DK, Xing C, Li Z, Dong B, Xing F, Fan D, Bao S, Zhang H, Cao Y. Proc Natl Acad Sci USA, 2018, 115: 501–506

    Article  CAS  Google Scholar 

  132. Sun C, Wen L, Zeng J, Wang Y, Sun Q, Deng L, Zhao C, Li Z. Biomaterials, 2016, 91: 81–89

    Article  CAS  Google Scholar 

  133. Liu Z, Chen H, Jia Y, Zhang W, Zhao H, Fan W, Zhang W, Zhong H, Ni Y, Guo Z. Nanoscale, 2018, 10: 18795–18804

    Article  CAS  Google Scholar 

  134. Sun C, Xu Y, Deng L, Zhang H, Sun Q, Zhao C, Li Z. ACS Appl Bio Mater, 2018, 1: 673–682

    Article  CAS  Google Scholar 

  135. Liu J, Liu T, Du P, Zhang L, Lei J. Angew Chem Int Ed, 2019, 58: 7808–7812

    Article  CAS  Google Scholar 

  136. Fojtů M, Chia X, Sofer Z, Masařík M, Pumera M. Adv Funct Mater, 2017, 27: 1701955

    Article  Google Scholar 

  137. Chen L, Chen C, Chen W, Li K, Chen X, Tang X, Xie G, Luo X, Wang X, Liang H, Yu S. ACS Appl Mater Interfaces, 2018, 10: 21137–21148

    Article  CAS  Google Scholar 

  138. Liang X, Ye X, Wang C, Xing C, Miao Q, Xie Z, Chen X, Zhang X, Zhang H, Mei L. J Control Release, 2019, 296: 150–161

    Article  CAS  Google Scholar 

  139. Lin J, Li Q, Zeng X, Chen Z, Ding Q, Li Y, Zhou H, Meng X, Chen D, Deng Z, Hong X, Xiao Y. Sci China Chem, 2020, 63: 766–770

    Article  CAS  Google Scholar 

  140. Niu X, Li Y, Shu H, Wang J. J Phys Chem Lett, 2016, 7: 370–375

    Article  CAS  Google Scholar 

  141. Yang X, Wang D, Zhu J, Xue L, Ou C, Wang W, Lu M, Song X, Dong X. Chem Sci, 2019, 10: 3779–3785

    Article  Google Scholar 

  142. Fu Q, Li Z, Ye J, Li Z, Fu F, Lin SL, Chang CA, Yang H, Song J. Theranostics, 2020, 10: 4997–5010

    Article  CAS  Google Scholar 

  143. Fu Q, Zhu R, Song J, Yang H, Chen X. Adv Mater, 2018, 1805875

  144. Jana D, Jia S, Bindra AK, Xing P, Ding D, Zhao Y. ACS Appl Mater Interfaces, 2020, 12: 18342–18351

    Article  CAS  Google Scholar 

  145. Li Z, Xu H, Shao J, Jiang C, Zhang F, Lin J, Zhang H, Li J, Huang P. Appl Mater Today, 2019, 15: 297–304

    Article  Google Scholar 

  146. Deng L, Xu Y, Sun C, Yun B, Sun Q, Zhao C, Li Z. Sci Bull, 2018, 63: 917–924

    Article  CAS  Google Scholar 

  147. Zheng T, Zhou T, Feng X, Shen J, Zhang M, Sun Y. ACS Appl Mater Interfaces, 2019, 11: 31615–31626

    Article  CAS  Google Scholar 

  148. Li Z, Fu Q, Ye J, Ge X, Wang J, Song J, Yang H. Angew Chem Int Ed, 2020, 59: 22202–22209

    Article  CAS  Google Scholar 

  149. Zhang R, Zhang Y, Dong ZC, Jiang S, Zhang C, Chen LG, Zhang L, Liao Y, Aizpurua J, Luo Y, Yang JL, Hou JG. Nature, 2013, 498: 82–86

    Article  CAS  Google Scholar 

  150. Yang G, Liu Z, Li Y, Hou Y, Fei X, Su C, Wang S, Zhuang Z, Guo Z. Biomater Sci, 2017, 5: 2048–2055

    Article  CAS  Google Scholar 

  151. Ribeiro HB, Pimenta MA, de Matos CJS. J Raman Spectrosc, 2018, 49: 76–90

    Article  CAS  Google Scholar 

  152. Ma S, Li Q, Yin Y, Yang J, Liu D. Small, 2017, 13: 1603340

    Article  Google Scholar 

  153. Meng X, Wang X, Cheng Z, Tian N, Lang MC, Yan W, Liu D, Zhang Y, Wang P. ACS Appl Mater Interfaces, 2018, 10: 31136–31145

    Article  CAS  Google Scholar 

  154. Guo T, Ding F, Li D, Zhang W, Cao L, Liu Z. Appl Sci, 2019, 9: 398

    Article  CAS  Google Scholar 

  155. Sun C, Lee JSH, Zhang M. Adv Drug Deliver Rev, 2008, 60: 1252–1265

    Article  CAS  Google Scholar 

  156. Liu J, Du P, Liu T, Córdova Wong BJ, Wang W, Ju H, Lei J. Biomaterials, 2019, 192: 179–188

    Article  CAS  Google Scholar 

  157. Wu F, Zhang M, Chu X, Zhang Q, Su Y, Sun B, Lu T, Zhou N, Zhang J, Wang J, Yi X. Chem Eng J, 2019, 370: 387–399

    Article  CAS  Google Scholar 

  158. Zhang M, Wang W, Cui Y, Zhou N, Shen J. IJN, 2018, Volume 13: 2803–2819

    Article  CAS  Google Scholar 

  159. Guo T, Lin Y, Jin G, Weng R, Song J, Liu X, Huang G, Hou L, Yang H. Chem Commun, 2019, 55: 850–853

    Article  CAS  Google Scholar 

  160. Xu M, Yang G, Bi H, Xu J, Dong S, Jia T, Wang Z, Zhao R, Sun Q, Gai S, He F, Yang D, Yang P. Chem Eng J, 2020, 382: 122822

    Article  CAS  Google Scholar 

  161. Shin TH, Choi Y, Kim S, Cheon J. Chem Soc Rev, 2015, 44: 4501–4516

    Article  CAS  Google Scholar 

  162. Zhang M, Wang W, Wu F, Graveran K, Zhang J, Wu C. Chem Eur J, 2018, 24: 12890–12901

    Article  CAS  Google Scholar 

  163. Hu K, Xie L, Zhang Y, Hanyu M, Yang Z, Nagatsu K, Suzuki H, Ouyang J, Ji X, Wei J, Xu H, Farokhzad OC, Liang SH, Wang L, Tao W, Zhang MR. Nat Commun, 2020, 11: 2778

    Article  CAS  Google Scholar 

  164. Luo M, Zhou Y, Gao N, Cheng W, Wang X, Cao J, Zeng X, Liu G, Mei L. Chem Eng J, 2020, 385: 123942

    Article  CAS  Google Scholar 

  165. Zhang M, Sheng B, Ashley J, Zheng T, Wang W, Zhang Q, Zhang J, Zhou N, Shen J, Sun Y. Sens Actuat B-Chem, 2020, 307: 127491

    Article  Google Scholar 

  166. Luo M, Cheng W, Zeng X, Mei L, Liu G, Deng W. Pharmaceutics, 2019, 11: 242

    Article  CAS  Google Scholar 

  167. Poudel BK, Hwang J, Ku SK, Kim JO, Byeon JH. NPG Asia Mater, 2018, 10: 727–739

    Article  CAS  Google Scholar 

  168. Su C, Zhong H, Chen H, Guo Y, Guo Z, Huang D, Zhang W, Wu Q, Yang B, Liu Z. New J Chem, 2019, 43: 8620–8626

    Article  CAS  Google Scholar 

  169. Liu MD, Yu Y, Guo DK, Wang SB, Li CX, Gao F, Zhang C, Xie BR, Zhong Z, Zhang XZ. Nanoscale, 2020, 12: 8890–8897

    Article  CAS  Google Scholar 

  170. Ouyang J, Deng Y, Chen W, Xu Q, Wang L, Liu Z, Tang F, Deng L, Liu YN. J Mater Chem B, 2018, 6: 2057–2064

    Article  CAS  Google Scholar 

  171. Hai L, Zhang A, Wu X, Cheng H, He D, Wang T, He X, Wang K. ACS Appl Nano Mater, 2019, 3: 563–575

    Article  Google Scholar 

  172. Li Y, Liu Z, Hou Y, Yang G, Fei X, Zhao H, Guo Y, Su C, Wang Z, Zhong H, Zhuang Z, Guo Z. ACS Appl Mater Interfaces, 2017, 9: 25098–25106

    Article  CAS  Google Scholar 

  173. Ou M, Lin C, Wang Y, Lu Y, Wang W, Li Z, Zeng W, Zeng X, Ji X, Mei L. J Control Release, 2022, 345: 755–769

    Article  CAS  Google Scholar 

  174. Zhang D, Lin Z, Lan S, Sun H, Zeng Y, Liu X. Mater Chem Front, 2019, 3: 656–663

    Article  CAS  Google Scholar 

  175. Yang X, Wang D, Shi Y, Zou J, Zhao Q, Zhang Q, Huang W, Shao J, Xie X, Dong X. ACS Appl Mater Interfaces, 2018, 10: 12431–12440

    Article  CAS  Google Scholar 

  176. Zhang J, Ma Y, Hu K, Feng Y, Chen S, Yang X, Fong-Chuen Loo J, Zhang H, Yin F, Li Z. Bioconjugate Chem, 2019, 30: 1658–1664

    Article  CAS  Google Scholar 

  177. Wang S, Weng J, Fu X, Lin J, Fan W, Lu N, Qu JL, Chen S, Wang T, Huang P. Nanotheranostics, 2017, 1: 208–216

    Article  Google Scholar 

  178. Chen BQ, Kankala RK, Zhang Y, Xiang ST, Tang HX, Wang Q, Yang DY, Wang SB, Zhang YS, Liu G, Chen AZ. Chem Eng J, 2020, 390: 124312

    Article  CAS  Google Scholar 

  179. Huang X, Wu B, Li J, Shang Y, Chen W, Nie X, Gui R. Artif Cells Nanomed Biotechnol, 2019, 47: 968–979

    Article  CAS  Google Scholar 

  180. Wang H, Zhong L, Liu Y, Xu X, Xing C, Wang M, Bai SM, Lu CH, Yang HH. Chem Commun, 2018, 54: 3142–3145

    Article  CAS  Google Scholar 

  181. Zhou W, Cui H, Ying L, Yu XF. Angew Chem Int Ed, 2018, 57: 10268–10272

    Article  CAS  Google Scholar 

  182. Qian X, Zheng Y, Chen Y. Adv Mater, 2016, 28: 8097–8129

    Article  CAS  Google Scholar 

  183. Chen T, Zeng W, Tie C, Yu M, Hao H, Deng Y, Li Q, Zheng H, Wu M, Mei L. Bioactive Mater, 2022, 10: 515–525

    Article  CAS  Google Scholar 

  184. Li Z, Zhang T, Fan F, Gao F, Ji H, Yang L. J Phys Chem Lett, 2020, 11: 1228–1238

    Article  CAS  Google Scholar 

  185. Chen X, Song J, Chen X, Yang H. Chem Soc Rev, 2019, 48: 3073–3101

    Article  CAS  Google Scholar 

  186. Ma Y, Zhang Y, Li X, Zhao Y, Li M, Jiang W, Tang X, Dou J, Lu L, Wang F, Wang Y. ACS Nano, 2019, 13: 11967–11980

    Article  CAS  Google Scholar 

  187. Deng G, Sun Z, Li S, Peng X, Li W, Zhou L, Ma Y, Gong P, Cai L. ACS Nano, 2018, 12: 12096–12108

    Article  CAS  Google Scholar 

  188. Ou W, Byeon JH, Soe ZC, Kim BK, Thapa RK, Gupta B, Poudel BK, Ku SK, Yong CS, Kim JO. Theranostics, 2019, 9: 6780–6796

    Article  CAS  Google Scholar 

  189. Wan S, Zhang B, Li S, He B, Pu Y. J Mater Chem B, 2020, 8: 2805–2813

    Article  CAS  Google Scholar 

  190. Zhao H, Chen H, Guo Z, Zhang W, Yu H, Zhuang Z, Zhong H, Liu Z. Chem Eng J, 2020, 394: 124314

    Article  CAS  Google Scholar 

  191. Kondo Y, Kanzawa T, Sawaya R, Kondo S. Nat Rev Cancer, 2005, 5: 726–734

    Article  CAS  Google Scholar 

  192. Yang ZJ, Chee CE, Huang S, Sinicrope FA. Mol Cancer Ther, 2011, 10: 1533–1541

    Article  CAS  Google Scholar 

  193. White E, DiPaola RS. Clin Cancer Res, 2009, 15: 5308–5316

    Article  Google Scholar 

  194. Zhou W, Pan T, Cui H, Zhao Z, Chu PK, Yu XF. Angew Chem Int Ed, 2019, 58: 769–774

    Article  CAS  Google Scholar 

  195. Yang B, Ding L, Chen Y, Shi J. Adv Sci, 2020, 7: 1902847

    Article  CAS  Google Scholar 

  196. Lim Y-, Zhou W-, Li G, Hu Z-, Hong L, Yu X-, Li Y-. ChemNanoMat, 2019, 5: 606–611

    Article  CAS  Google Scholar 

  197. Li X, Yang Y, Zhao H, Zhu T, Yang Z, Xu H, Fu Y, Lin F, Pan X, Li L, Cui C, Hong M, Yang L, Wang KK, Tan W. J Am Chem Soc, 2020, 142: 3862–3872

    Article  CAS  Google Scholar 

  198. Xiao F, Lin L, Chao Z, Shao C, Chen Z, Wei Z, Lu J, Huang Y, Li L, Liu Q, Liang Y, Tian L. Angew Chem Int Ed, 2020, 59: 9702–9710

    Article  CAS  Google Scholar 

  199. Jin L, Hu P, Wang Y, Wu L, Qin K, Cheng H, Wang S, Pan B, Xin H, Zhang W, Wang X. Adv Mater, 2020, 32: 1906050

    Article  CAS  Google Scholar 

  200. Chen W, Ouyang J, Yi X, Xu Y, Niu C, Zhang W, Wang L, Sheng J, Deng L, Liu YN, Guo S. Adv Mater, 2018, 30: 1703458

    Article  Google Scholar 

  201. Hou J, Wang H, Ge Z, Zuo T, Chen Q, Liu X, Mou S, Fan C, Xie Y, Wang L. Nano Lett, 2020, 20: 1447–1454

    Article  CAS  Google Scholar 

  202. Lee YB, Song SJ, Shin YC, Jung YJ, Kim B, Kang MS, Kwon IK, Hyon SH, Lee HU, Jung SH, Lim D, Han DW. J Industrial Eng Chem, 2019, 80: 802–810

    Article  CAS  Google Scholar 

  203. Qing Y, Li R, Li S, Li Y, Wang X, Qin Y. IJN, 2020, Volume 15: 2045–2058

    Article  CAS  Google Scholar 

  204. Liu X, MillerII AL, Park S, George MN, Waletzki BE, Xu H, Terzic A, Lu L. ACS Appl Mater Interfaces, 2019, 11: 23558–23572

    Article  CAS  Google Scholar 

  205. Wang Z, Zhao J, Tang W, Hu L, Chen X, Su Y, Zou C, Wang J, Lu WW, Zhen W, Zhang R, Yang D, Peng S. Small, 2019, 15: 1901560

    Article  CAS  Google Scholar 

  206. Shao J, Ruan C, Xie H, Chu PK, Yu XF. Adv Sci, 2020, 7: 2000439

    Article  CAS  Google Scholar 

  207. Cheng L, Cai Z, Zhao J, Wang F, Lu M, Deng L, Cui W. Bioactive Mater, 2020, 5: 1026–1043

    Article  Google Scholar 

  208. Yang B, Yin J, Chen Y, Pan S, Yao H, Gao Y, Shi J. Adv Mater, 2018, 30: 1705611

    Article  Google Scholar 

  209. Plutnar J, Sofer Z, Pumera M. ACS Nano, 2018, 12: 8390–8396

    Article  CAS  Google Scholar 

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Acknowledgements

This work was supported by the National Key Research and Development Program of China (No. 2020YFA0210800), the Major Project of Science and Technology of Fujian Province (2020HZ06006), the National Natural Science Foundation of China (No. 22027805, 21804068, U21A20377 and 21874024), the joint re-search projects of Health and Education Commission of Fujian Province (No. 2019-WJ-20), and the Natural Science Foundation of Fujian Province (No. 2020J02012).

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  1. MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, 350108, China

    Zhi Li, Jibin Song & Huanghao Yang

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  1. Zhi Li
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Li, Z., Song, J. & Yang, H. Emerging low-dimensional black phosphorus: from physical-optical properties to biomedical applications. Sci. China Chem. 66, 406–435 (2023). https://doi.org/10.1007/s11426-022-1355-6

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