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Determination of PCDD/Fs and dioxin-like PCBs in food and feed using gas chromatography-triple quadrupole mass spectrometry

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Abstract

A method was developed on a gas chromatograph coupled to a triple quadrupole mass spectrometer (GC-MS/MS) for trace level determination of polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (DL-PCBs) in food and feed. The results demonstrated good sensitivity and repeatability for PCDD/Fs and DL-PCBs at an extremely low level (10 pg mL−1 for 2,3,7,8-TCDD/F), as well as wide linear response of over 3 or 4 orders of magnitude in concentration ranges; 0.5–200 ng mL−1 for PeCDD/F and 0.2–2000 ng mL−1 for DL-PCBs. The method detection limits for PCDD/Fs and DL-PCBs were in the range from 0.018–0.17 pg g−1 to 0.13–0.36 pg g−1, respectively. The performance of the GC-MS/MS for food and feed sample analysis showed high precision and accuracy compared to the high resolution gas chromatograph/high resolution mass spectrometer. The results indicated the feasibility of GC-MS/MS as a confirmatory method for the measurement of PCDD/Fs and DL-PCBs in food and feed as required by European Union legislation.

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Acknowledgments

This work was supported by the National Natural Science Foundation of China (21477156, 21477155, 41276195), Chinese Academy of Sciences (XDB14010100) and the National Basic Research Program of China (2015CB453101). We greatly thank Miss Feifei Tian from Analytical Applications Center, Shimadzu (China) Co. Ltd for technical assistance on GC-MS/MS.

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Authors and Affiliations

  1. State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China

    Huizhong Sun, Pu Wang, Honghua Li, Yingming Li, Shucheng Zheng, Julius Matsiko, Yanfen Hao, Weiwei Zhang, Dou Wang & Qinghua Zhang

  2. University of Chinese Academy of Sciences, Beijing, 100049, China

    Huizhong Sun, Shucheng Zheng, Julius Matsiko, Yanfen Hao, Weiwei Zhang, Dou Wang & Qinghua Zhang

  3. Institute of Environment and Health, Jianghan University, Wuhan, 430056, China

    Qinghua Zhang

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  1. Huizhong Sun
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  2. Pu Wang
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  3. Honghua Li
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  4. Yingming Li
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  5. Shucheng Zheng
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  7. Yanfen Hao
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  8. Weiwei Zhang
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  9. Dou Wang
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  10. Qinghua Zhang
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Correspondence to Qinghua Zhang.

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11426_2016_9017_MOESM1_ESM.docx

Determination of PCDD/Fs and dioxin-like PCBs in food and feed using gas chromatography-triple quadrupole mass spectrometry

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Sun, H., Wang, P., Li, H. et al. Determination of PCDD/Fs and dioxin-like PCBs in food and feed using gas chromatography-triple quadrupole mass spectrometry. Sci. China Chem. 60, 670–677 (2017). https://doi.org/10.1007/s11426-016-9017-9

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  • DOI: https://doi.org/10.1007/s11426-016-9017-9

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