Science China Chemistry

, Volume 58, Issue 12, pp 1898–1905 | Cite as

Inorganic arsenic contamination of rice from Chinese major rice-producing areas and exposure assessment in Chinese population

  • Xiaowei Li
  • Ke Xie
  • Bing Yue
  • Yunyun Gong
  • Yi Shao
  • Xiaohong Shang
  • Yongning Wu
Articles

Abstract

This study examined the total arsenic (Ast) and inorganic arsenic (Asi) content in the main rice growing area of China. The results were compared with other countries and then used for dietary exposure assessment. A total of 446 rice samples from 15 main rice-growing provinces and autonomous regions of China were collected and then divided into unpolished and polished rice. Total arsenic and arsenic species were analyzed in a total of 892 subsamples using inductively coupled plasma-mass spectrometry (ICP-MS) and high performance liquid chromatography (HPLC) coupled ICP-MS, respectively. National Ast means were 255 μg/kg of unpolished rice and 143 μg/kg of polished rice. Asi was found to be the predominant species and mean levels were 209 μg/kg of unpolished rice and 108 μg/kg of polished rice, respectively. Exposure assessment to Asi in polished rice has been calculated for the margin of exposure (MOE), which highlights the fact that Asi levels in the Chinese rice should arouse public health concern.

Keywords

arsenic speciation exposure assessment inorganic arsenic rice 

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References

  1. 1.
    Chatterjee D, Halder D, Majumder S, Biswas A, Nath B, Bhattacharya P, Bhowmicka S, Mukherjee-Goswamia A, Sahaa D, Hazraa R, Maityd P, Chatterjeee D, Mukherjeef A, Bundschuh J. Assessment of arsenic exposure from groundwater and rice in Bengal Delta Region, West Bengal, India. Water Res, 2010, 44:5803–5812CrossRefGoogle Scholar
  2. 2.
    Breslow N, Day N. Statistical Methods in Cancer Research. Vol. 2. Lyon: IARC, 1987Google Scholar
  3. 3.
    Chen CJ, Wang CJ. Ecological correlation between arsenic level in well water and age-adjusted mortality from malignant neoplasms. Cancer Res, 1990, 50:5470–5474Google Scholar
  4. 4.
    Chen GQ, Zhou L, Styblo M, Walton F, Jing Y, Weinberg R, Chen Z, Waxman S. Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells. Cancer Res, 2003, 63:1853–1859Google Scholar
  5. 5.
    Nishikawa T, Wanibuchi H, Ogawa M, Kinoshita A, Morimura K, Hiroi T, Funae Y, Kishida H, Nakae D, Fukushima S. Promoting effects of monomethylarsonic acid, dimethylarsinic acid and trimethylarsine oxide on induction of rat liver preneoplastic glutathione S-transferase placental form positive foci: a possible reactive oxygen species mechanism. Int J Cancer, 2002, 100:136–139CrossRefGoogle Scholar
  6. 6.
    Gallagher PA, Wei X, Shoemaker JA, Brockhoff CA, Creed JT. Detection of arsenosugars from kelp extracts via IC-electrospray ionization-MS-MS and IC membrane hydride generation ICP-MS. J Anal At Spectrom, 1999, 14:1829–1834CrossRefGoogle Scholar
  7. 7.
    Meharg AA, Lombi E, Williams PN, Scheckel KG, Feldmann J, Raab AZ, Zhu Y, Islam R. Speciation and localization of arsenic in white and brown rice grains. Environ Sci Techno, 2008, 42:1051–1057CrossRefGoogle Scholar
  8. 8.
    Schoof R, Yost L, Eickhoff J, Crecelius E, Cragin D, Meacher D, Menzel D. A market basket survey of inorganic arsenic in food. Food Chem Toxicol, 1999, 37:839–846CrossRefGoogle Scholar
  9. 9.
    Tao SSH, Bolger PM. Dietary arsenic intakes in the United States: FDA total diet study, September 1991–December 1996. Food Addit Contam, 1999, 16:465–472CrossRefGoogle Scholar
  10. 10.
    Heitkemper DT, Vela NP, Stewart KR, Westphal CS. Determination of total and speciated arsenicin rice by ion chromatography and inductively coupled plasma mass spectrometry. J Anal At Spectrom, 2001, 16:299–306CrossRefGoogle Scholar
  11. 11.
    Smith NM, Lee R, Heitkemper DT, DeNicola Cafferky K, Haque A, Henderson AK. Inorganic arsenic in cooked rice and vegetables from Bangladeshi households. Sci Total Environ, 2006, 370:294–301CrossRefGoogle Scholar
  12. 12.
    Williams P, Price A, Raab A, Hossain S, Feldmann J, Meharg A. Variation in arsenic speciation and concentration in paddy rice related to dietary exposure. Environ Sci Technol, 2005, 39:5531–5540CrossRefGoogle Scholar
  13. 13.
    Abedin, MJ, Feldmann J, Meharg AA. Uptake kinetics of arsenic species in rice plants. Plant Physiol, 2002, 128:1120–1128CrossRefGoogle Scholar
  14. 14.
    Bednar A, Garbarino J, Ranville J, Wildeman T. Presence of organoarsenicals used in cotton production in agricultural water and soil of the southern United States. J Agric Food Chem, 2002, 50:7340–7344CrossRefGoogle Scholar
  15. 15.
    Lee JS, Lee SW, Chon HT, Kim KW. Evaluation of human exposure to arsenic due to rice ingestion in the vicinity of abandoned Myungbong Au-Ag mine site, Korea. J Geochem Explorat, 2008, 96:231–235CrossRefGoogle Scholar
  16. 16.
    Marin A, Masscheleyn P, Patrick W. The influence of chemical form and concentration of arsenic on rice growth and tissue arsenic concentration. Plant Soil, 1992, 139:175–183CrossRefGoogle Scholar
  17. 17.
    Odanaka Y, Tsuchiya N, Matano O, Goto S. Characterization of arsenic metabolites in rice plant treated with DSMA (disodium methanearsonate). J Agric Food Chem, 1985, 33:757–763CrossRefGoogle Scholar
  18. 18.
    Williams P, Raab A, Feldmann J, Meharg A. Market basket survey shows elevated levels of As in South Central US processed rice compared to California: consequences for human dietary exposure. Environ Sci Technol, 2007, 41:2178–2183CrossRefGoogle Scholar
  19. 19.
    Li Y. Research and practice of water-saving irrigation for rice in China. In: Barker R, Loeve R, Li YH, Tuong TP, Eds. Water-Saving Irrigation for Rice: Proceedings of an International Workshop Held in Wuhan, China. Wuhan: International Water Management Institure, 2011. 23–25Google Scholar
  20. 20.
    Lin HT, Wong SS, Li GC. Heavy metal content of rice and shellfish in Taiwan. J Food Drug Anal, 2004, 12:167–174Google Scholar
  21. 21.
    The National Bureau of Statistics. National food production Gazette (in Chinese). http://www.gov.cn/gzdt/2011-12/02/content2008844.htm. 2011-12-02
  22. 22.
    Zhu YG, Sun GX, Lei M, Teng M, Liu YX, Chen NC, Wang LH, Carey AM, Deacon C, Raab A, Meharg AA, Williams PN. High percentage inorganic arsenic content of mining impacted and nonimpacted Chinese rice. Environ Sci Technol, 2008, 42:5008–5013CrossRefGoogle Scholar
  23. 23.
    Cheng W, Zhang G, Yao H, Dominy P, Wu W, Wang R. Possibility of predicting heavy-metal contents in rice grains based on DTPA-extracted levels in soil. Commun Soil Sci Plant Anal, 2004, 35:2731–2745CrossRefGoogle Scholar
  24. 24.
    Huang RQ, Gao SF, Wang WL, Staunton S, Wang G. Soil arsenic availability and the transfer of soil arsenic to crops in suburban areas in Fujian Province, southeast China. Sci Total Environ, 2006, 368:531–541CrossRefGoogle Scholar
  25. 25.
    Li G, Sun GX, Williams PN, Nunes L, Zhu YG. Inorganic arsenic in Chinese food and its cancer risk. Environ Int, 2011, 37:1219–1225CrossRefGoogle Scholar
  26. 26.
    World Health Organization. Guidelines for Drinking-Water Quality. 3 ed. Geneva: WHO, 2006. p488–493Google Scholar
  27. 27.
    Juhasz AL, Smith E, Weber J, Rees M, Rofe A, Kuchel T, Sansom L, Naidu R. In vivo assessment of arsenic bioavailability in rice and its significance for human health risk assessment. Environ Health Perspect, 2006, 114:1826–1831Google Scholar
  28. 28.
    Yang XG, Zhai FY. The Second China National Nutrition and Health Survey Report: Diet and Nutrient Intake Status in 2002. Beijing: People’s Medical Publishing House, 2006Google Scholar
  29. 29.
    Batista BL, Souza JMO, De Souza SS, Barbosa F. Speciation of arsenic in rice and estimation of daily intake of different arsenic species by Brazilians through rice consumption. J Hazard Mater, 2011, 191:342–348CrossRefGoogle Scholar
  30. 30.
    D’Amato M, Forte G, Caroli S. Identification and quantification of major species of arsenic in rice. J AOAC Int, 2004, 87:238–243Google Scholar
  31. 31.
    Sanz E, Munoz-Olivas R, Camara C, Sengupta MK, Ahamed S. Arsenic speciation in rice, straw, soil, hair and nails samples from the arsenic-affected areas of Middle and Lower Ganga plain. J Environ Sci Health A, 2007, 42:1695–1705CrossRefGoogle Scholar
  32. 32.
    FAPAS. Protocol for Proficiency Testing Schemes. 2 ed. Sand Hutton, YORK: Fera Science Ltd., 2010Google Scholar
  33. 33.
    Liang F, Li Y, Zhang G, Tan M, Lin J, Liu W, Li Y, Lu W. Total and speciated arsenic levels in rice from China. Food Addit Contam, 2010, 27:810–816CrossRefGoogle Scholar
  34. 34.
    Ministry of Health. National Food Safety Standard Maximum Levels of Contaminants in Food. GB 2762-2012. Beijing: Standards Press of China, 2012Google Scholar
  35. 35.
    Heinemann R, Fagundes P, Pinto E, Penteado M, Lanfer-Marquez U. Comparative study of nutrient composition of commercial brown, parboiled and milled rice from Brazil. J Food Comp Anal, 2005, 18:287–296CrossRefGoogle Scholar
  36. 36.
    Codex Committee on Contaminants in Foods. Discussion Paper on Arsenic in Rice. Codex Committee on Contaminants in Foods, 5 th Session. CX/CF/11/5/10. Hague, Netherlands, 2011Google Scholar
  37. 37.
    Codex Committee on Contaminants in Foods. Proposed Draft Maximum Levels for Arsenic in Rice. Codex Committee on Contaminants in Foods, 6 th Session. CX/CF/12/6/8, 2012Google Scholar
  38. 38.
    Codex Committee on Contaminants in Foods. Proposed Draft Maximum Levels for Arsenic in Rice (Raw and Polished Rice). Codex Committee on Contaminants in Foods, 8th Session. CX/CF/14/8/6, 2014Google Scholar
  39. 39.
    EFSA. Scientific Opinion on Arsenic in Food. EFSA Panel on Contaminants in the Food Chain (CONTAM), 2009:1351–1550Google Scholar
  40. 40.
    World Health Organization. Evaluation of certain food additives and contaminants in food. Seventy-second report of the Joint FAO/WHO Expert Committee on Food Additives. WHO Technical Report Series. Rome, 2011Google Scholar

Copyright information

© Science China Press and Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  • Xiaowei Li
    • 1
  • Ke Xie
    • 1
    • 2
  • Bing Yue
    • 1
  • Yunyun Gong
    • 1
    • 3
  • Yi Shao
    • 1
  • Xiaohong Shang
    • 1
  • Yongning Wu
    • 1
    • 2
  1. 1.Key Laboratory of Food Safety Risk Assessment, Ministry of HealthChina National Center for Food Safety Risk AssessmentBeijingChina
  2. 2.Food Science and Engineering DepartmentWuhan Polytechnic UniversityWuhanChina
  3. 3.Institute for Global Food Security, School of Biological SciencesQueen’s University of BelfastBelfastUK

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