Abstract
We demonstrated here a new family of multi-responsive polymer: wholly aromatic sulfonated polyamide (SPA). SPA exhibited the unusual response to temperature and pH with the tunable low critical solution temperature (LCST). LCST of the obtained SPA decreased sharply with the increasing pH, and the difference of LCST between pH 6.0–6.8 is about 60 °C.
References
Pasparakis G, Vamvakaki M. Multiresponsive polymers: Nano-sized assemblies, stimuli-sensitive gels and smart surfaces. Polym Chem, 2011, 2: 1234–1248
Lutz JF, Akdemir Ö, Hoth A. Point by point comparison of two thermosensitive polymers exhibiting a similar LCST: Is the age of poly(NIPAM) over. J Am Chem Soc, 2006, 128: 13046–13047
Gil ES, Hudson SM. Stimuli-responsive polymers and their bioconjugates. Prog Polym Sci, 2004, 29: 1173–1222
Zhou L, Yu L, Ding M, Li J, Tan H, Wang Z, Fu Q, Synthesis and characterization of pH-sensitive biodegradable polyurethane for potential drug delivery applications. Macromolecules, 2011, 44: 857–864
Qian J, Wu F, Preparation of supramolecular graft copolymers and the subsequent formation of pH-sensitive vesicles. Chem Mater, 2009, 21: 758–762
Lutz JF. Thermo-switchable materials prepared using the OEGMA-platform. Adv Mater, 2011, 23: 2237–2243
Hoogenboom R, Thijs HML, Jochems MJHC, Lankvelt BM, Fijten MW M, Schubert US. Tuning the LCST of poly(2-oxazoline)s by varying composition and molecular weight: Alternatives to poly(N-isopropylacrylamide). Chem Commun, 2008, 5758-5760
Kempe K, Neuwirth T, Czaplewska J, Gottschaldt M, Hoogenboom R, Schubert US. Cross-linked hyperbranched polyglycerols as hosts for selective binding of guest molecules. Polym Chem, 2011, 2: 1737–1743
Ren YR, Jiang XS, Yin J. Poly(ether tert-amine): A novel family of multiresponsive polymer. J Polym Sci Part A: Polym Chem, 2009, 47: 1292–1297
Zhong Z, Song Y, Engbersen JFJ, Lok MC, Hennink WE, Feijen J. A versatile family of degradable non-viral gene carriers based on hyperbranched poly(ester amine)s. J Control Release, 2005, 109: 317–329
Li Y, Zhu, YD, Xia, KJ, Sheng RL, Jia L, Hou XD, Xu YH, Cao A. Dendritic poly(L-lysine)-b-poly(L-lactide)-b-dendritic poly(L-lysine) amphiphilic gene delivery vectors: Roles of PLL dendritic generation and enhanced transgene efficacies via termini modification. Biomacromolecules, 2009, 10: 2284–2293
Burakowska E, Quinn JR, Zimmerman SC, Haag R. Cross-linked hyperbranched polyglycerols as hosts for selective binding of guest molecules. J Am Chem Soc, 2009, 131: 10574–10580
Zhao Y, Tremblay L, Zhao Y. Phototunable LCST of water-soluble polymers: Exploring a topological effect. Macromolecules, 2011, 44: 4007–4011
Pang Y, Zhu Q, Zhou D, Liu JY, Chen Y, Su Y, Yan DY, Zhu XY, Zhu BS. Synthesis of backbone thermo and pH dual-responsive hyperbranched poly(amine-ether)s through proton-transfer polymerization. J Polym Sci Part A: Polym Chem, 2011, 4: 966–975
Prevot M, Déjugnat C, Möhwald H, Sukhorukov GB. Behavior of temperature-sensitive PNIPAM confined in polyelectrolyte capsules. ChemPhysChem, 2006, 7: 2497–2502
Zhang YJ, Furyk S, Bergbreiter DE, Cremer PS. Specific ion effects on the water solubility of macromolecules: PNIPAM and the hofmeister series. J Am Chem Soc, 2005, 127:14505–14510
Yin X, Stöver HDH. Thermosensitive and pH-sensitive polymers based on maleic anhydride copolymers. Macromolecules, 2002, 35: 10178–10181
Kojima C, Yoshimura K, Harada A, Sakanishi Y, Kono K. Synthesis and characterization of hyperbranched poly(glycidol) modified with pH-and temperature-sensitive groups. Bioconjug Chem, 2009, 20: 1054–1057
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Rights and permissions
About this article
Cite this article
Zhao, J., Xu, H., Jiang, X. et al. Multi-responsive wholly aromatic sulfonated polyamide ultra-sensitive to pH value. Sci. China Chem. 55, 2503–2506 (2012). https://doi.org/10.1007/s11426-012-4687-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11426-012-4687-6