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Iron-mediated cross dehydrogenative coupling (CDC) of terminal alkynes with benzylic ethers and alkanes

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Abstract

Iron-mediated sp-sp3 C-C bond formation through the cross dehydrogenative coupling (CDC) of terminal alkynes with benzylic ethers or alkanes has been developed. The inexpensive iron salt is used as the catalyst to make this transformation environmentally benign.

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Authors and Affiliations

  1. State Key Laboratory of Natural and Biomimetic Drugs; School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China

    Shi-Kai Xiang, Bo Zhang, Li-He Zhang, YuXin Cui & Ning Jiao

  2. Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, East China Normal University, Shanghai, 200062, China

    Ning Jiao

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  1. Shi-Kai Xiang
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  2. Bo Zhang
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  3. Li-He Zhang
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  4. YuXin Cui
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Correspondence to Ning Jiao.

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Xiang, SK., Zhang, B., Zhang, LH. et al. Iron-mediated cross dehydrogenative coupling (CDC) of terminal alkynes with benzylic ethers and alkanes. Sci. China Chem. 55, 50–54 (2012). https://doi.org/10.1007/s11426-011-4435-3

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  • DOI: https://doi.org/10.1007/s11426-011-4435-3

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