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Combination of dynamic hollow fiber liquid-phase microextraction with HPLC analysis for the determination of UV filters in cosmetic products

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Abstract

A simple method based on hollow fiber liquid-phase microextraction (HF-LPME) followed by high performance liquid chromatography (HPLC) analysis was successfully developed for the determination of UV filters in cosmetic products. A canular extractor was assembled by mounting a hollow fiber inside an external tube with a tee-connector. The organic solvent was immobilized into the fiber to form a liquid membrane as the acceptor phase. The sample was continuously injected into the extractor and the UV filters were extracted from the aqueous sample into organic acceptor phase. The main parameters affecting HF-LPME including extraction solvent, sample volume, sample flow rate, pH values and ionic strength were investigated. Toluene has been verified to be suitable as the acceptor phase. Under the optimized HF-LPME conditions, the enrichment factors of five UV filters varying from 24 to 57 were achieved. The limits of detection for the five UV filters were in the range of 1–100 μg L−1. The relative standard deviations (RSDs) of HF-LPME and HPLC analysis were lower than 5.2%. The proposed method has been successfully applied to the analysis of the varied cosmetic products.

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Authors and Affiliations

  1. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, China

    HongYun Yang & GuangSheng Guo

  2. Beijing Key Laboratory for Analytical Methods and Instrumentation; Department of Chemistry, Tsinghua University, Beijing, 100084, China

    HongYun Yang, HaiFang Li, Jin-Ming Lin & MingYu Ding

  3. Naka Division, Hitachi High-Technologies Corporation, Hitachinaka, 312-8504, Japan

    Ito Masahito

Authors
  1. HongYun Yang
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  2. HaiFang Li
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  3. Ito Masahito
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  4. Jin-Ming Lin
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  5. GuangSheng Guo
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  6. MingYu Ding
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Correspondence to HaiFang Li.

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Yang, H., Li, H., Masahito, I. et al. Combination of dynamic hollow fiber liquid-phase microextraction with HPLC analysis for the determination of UV filters in cosmetic products. Sci. China Chem. 54, 1627–1634 (2011). https://doi.org/10.1007/s11426-011-4331-x

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  • DOI: https://doi.org/10.1007/s11426-011-4331-x

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