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Study on the interaction between palladium(II)-chlorpromazine hydrochloride and sodium tungstate by the resonance Rayleigh scattering, second-order scattering and frequency doubling scattering spectra and its analytical application

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Abstract

The interaction between palladium(II)-chlorpromazine hydrochloride and sodium tungstate was investigated by ultraviolet-visible absorption, resonance Rayleigh scattering (RRS), second-order scattering (SOS) and frequency doubling scattering (FDS) spectroscopy. In pH 5.3 Britton-Robinson (BR) buffer medium, chlorpromazine hydrochloride (CPZ) reacted with Pd(II) to form 2:1 cationic chelate, which further reacted with Na2WO4 to form a 1:1 ternary ion-association complex ([Pd(CPZ)2]·WO4). As a result, the signal intensities of RRS, SOS and FDS were enhanced greatly, and the enhancements of scattering were proportional to the CPZ concentration in a certain range. Their maximum wavelengths were located at 310 nm, 570 nm and 391 nm, respectively and the detection limits (3σ) were 1.6 ng/mL (RRS method), 3.2 ng/mL (SOS method) and 5.6 ng/mL (FDS method). The optimum reaction conditions, the influences of coexisting substances and analytical application were mainly investigated by RRS method due to its highest sensitivity. A highly sensitive, simple, rapid and new method had been proposed to determine CPZ in the pharmaceutical form and residue of CPZ in pork. In addition, the Gibbs free energy change (δG f) of ion-association reaction was computed by using B3LYP/3-21g*/LanL2dz method. The formation of ion-association and the reasons for the enhancement of RRS were also discussed.

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References

  1. British Pharmacopoeia. Her Majesty’s Stationary Office, London, 1993, 347

  2. US Pharmacopoeia XXIIth Rev. US Pharmacopoeial Convention, Rockville, MD, 1990, 294

  3. Ministery of Agriculture of the People’s Republic of China No. 193

  4. Zhang LT. pharmaceutical Analysis. Beijing: Central Radio TV university Press, 2002. 253–255

    Google Scholar 

  5. Puzanowski-Tarasiewicz H, Tarasiewicz M, Misiuk WA. Spectrophotometric determination of titanium(IV) with chlorpromazine hydrochloride. J Microchem, 1984, 29: 341–344

    Article  Google Scholar 

  6. Basavaiah K, Swamy JM. Application of potassium dichromate and iron-thiocyanate in the spectrophotometric investigations of phenothiazines. II Farmaco, 2001, 56: 579–585

    Article  CAS  Google Scholar 

  7. Cai FC, Chen ZH, Liu WB, Huang YM. Determination of chlorpromazine hydrochloride by direct spectrofluorimetry. J Southwest China Norm Univ (Nat Sci), 2002, 27: 739–741

    CAS  Google Scholar 

  8. Maslanka A, Krzek J. Densitometric high performance thin-layer chromatography identification and quantitative analysis of psychotropic drugs. J AOAC Int, 2005, 88: 70–79

    CAS  Google Scholar 

  9. Zimova N, Nemec I, Zima J. Determination of chlorpromazine and thioridazine by differential pulse voltammetry in acetonitrile medium. Talanta, 1986, 33: 467–470

    Article  CAS  Google Scholar 

  10. Li YH, Wang CY, Tian J, Liu XQ, You TY. Separation and detection of chlorpromazine hydrochloride and promethazine hydrochloride using electrochemiluminescence followed by capillary electrophoresis. Asian J Chem, 2008, 25: 3833–3848

    Google Scholar 

  11. Yang JD. Potassium ferricyanide-luminol-chemiluminescence system for the promazine hydrochloride and chlorpromazine hydrochloride. J Anal Chem, 2002, 30: 1529

    CAS  Google Scholar 

  12. Tang GF, Huang YM, Shi WB. Determination of chlorpromazine hydrochloride by a reverse flow injection with chemiluminescence detection. J Southwest China Norm Univ (Nat Sci), 2004, 29: 839–842

    CAS  Google Scholar 

  13. Han XN, Tang YH, Yu CL, Wang NN, Xiong XY. The determination of phenothiazines by a flow-injection chemiluminescence method. Chin J Pharm Anal, 2005, 25: 1527–1530

    CAS  Google Scholar 

  14. Du J, Zheng HZ, Huang CZ, Wen CY, Hao JY, Hu YF, Zhou DB, Liu L. Positive charged polymer as a probe for DNA determination by resonance light scattering. Anal Sci, 2009, 25: 727–730

    Article  CAS  Google Scholar 

  15. Long XF, Miao Q, Bi SP, Li DS, Zhang CH, Zhao H. Resonance Rayleigh scattering method for the recognition and determination of double-stranded DNA using amikacin. Talanta, 2004, 64: 366–374

    Article  CAS  Google Scholar 

  16. Li L, Song GW, Fang GR. Determination of bovine serum albumin in the form of its triple complex with Fe(bpy)(phen)SO4-myristylpyridinium bromide by resonance light-scattering technique. Chemia Analityczna, 2009, 54: 99–107

    CAS  Google Scholar 

  17. Li YF, Shen XW, Huang CZ. A coupled reagent of o-phthalaldehyde and sulfanilic acid for protein detection based on the measurements of light scattering signals with a common spectrofluorometer. Talanta, 2008, 75: 1041–1045

    Article  CAS  Google Scholar 

  18. Wei Q, Li Y, Dong W, Du B. Determination of protein in milk powder using 2-sulfophenylazo-rhodanine as a probe by the enhanced resonance Rayleigh light-scattering technique. J AOAC Int, 2006, 89(5): 1353–1359

    CAS  Google Scholar 

  19. Liu J, Liu ZF, Hu XL, Liu SP. Determination of chondroitin sulfate by resonance Rayleigh scattering and resonance non-linear scattering method with bovine serum albumin. J Southwest Univ (Nat Sci), 2010, 32(3): 30–33

    Google Scholar 

  20. Ma Y, Li NB, Luo HQ. Novel and sensitive methods for the determination of dopamine based on the resonance Rayleigh scattering, second-order scattering and frequency doubling scattering quenching effects. Spectrochimica Acta Part A, 2009, 73(4): 747–751

    Article  CAS  Google Scholar 

  21. Wang N, Dong ZZ, Xu SK, Wang NZ, Zhang XJ. Resonance Rayleigh scattering spectral method for the determination of procaine hydrochloride with nanogold as probe. Chin J Anal Chem, 2008, 36(7): 995–998

    CAS  Google Scholar 

  22. Li YF, Shen XW, Huang CZ, Wang J. Resonance light scattering method for the determination of tryptophan in compound amino acids injection. Chin J Anal Chem, 2008, 36(6): 819–822

    Article  CAS  Google Scholar 

  23. Jacobsohn M, Banin U. Size dependence of second harmonic generation in CdSe nanocrystal quantum Dots. J Pharm Biomed Anal, 2005, 37: 281–286

    Article  CAS  Google Scholar 

  24. Zhang X, Wang X, Ma M, Fu DG, Liu JZ, Gu M, Lu ZH, Xu L, Chen KJ. Study progress in second-order optical nonlinearitis of inorganic nanoparticles. Anal Sci, 2003, 19: 1055–1060

    Article  Google Scholar 

  25. Luo HQ, Liu SP, Li NB, Liu ZF. Resonance Rayleigh scattering, frequency doubling scattering and second-order scattering spectra of the heparin-crystal violetsystem and their analytical application. Anal Chim Acta, 2002, 468: 275–286

    Article  CAS  Google Scholar 

  26. Daniel D, Gutz IGR. Spectroelectrochemical determination of chlorpromazine hydrochloride by flow-injection analysis. J Pharm Biomed Anal, 2005, 37: 281–286

    Article  CAS  Google Scholar 

  27. Ministery of agriculture of the people’s republic of China No. 163

  28. Tang XL, Liu ZF, Liu SP, Hu XL. Study on the interaction between diphenhydramine and erythrosin by absorption, fluorescence and resonance Rayleigh scattering spectra. Science China Ser B: Chem, 2007, 50: 54–62

    Article  CAS  Google Scholar 

  29. Editorial board of encyclopedia of chemical engineering. Encyclopedia of chemical engineering. Beijing: Chemical Industry Press, 1997, 16: 1036–1037

    Google Scholar 

  30. Edition of editorial board of chinese macropaedia. Chinese macropaedia biology(II). Beijing: Chinese Macropaedia Press, 1991, 1374

    Google Scholar 

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Authors and Affiliations

  1. Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education; School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China

    PeiLi Chen, ShaoPu Liu, ZhongFang Liu, XiaoLi Hu & CuiXia Li

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  1. PeiLi Chen
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  2. ShaoPu Liu
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  3. ZhongFang Liu
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  5. CuiXia Li
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Correspondence to XiaoLi Hu.

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Chen, P., Liu, S., Liu, Z. et al. Study on the interaction between palladium(II)-chlorpromazine hydrochloride and sodium tungstate by the resonance Rayleigh scattering, second-order scattering and frequency doubling scattering spectra and its analytical application. Sci. China Chem. 54, 506–514 (2011). https://doi.org/10.1007/s11426-010-4126-5

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