Abstract
ABA triblock copolymers were synthesized by dihydroxyl-capped PEO initiated enzymatic ring-opening polymerization (eROP) of ε-CL in the presence of biocatalyst Novozyme 435. The chains ended with hydroxyl of block copolymers were modified by the esterification of 2,2-dichloro acetyl chloride (DCAC) to obtain the tetrafunctional macroinitiator, which was used in the ATRP of 4-vinylpyridine (4-VP). CuCl/HMTETA was used as the catalyst system in the ATRP of 4-VP to acquire the H-shaped block copolymers (PVP)2-b-PCL-b-PEG-b-PCL-b-(PVP)2. The H-shaped block copolymers were characterized by FTIR, NMR, and GPC. Copolymers with high molecular weights (M n = 46121 g/mol) and low polydispersities (M w/M n = 1.30) were prepared. Moreover, the morphology of the copolymer was examined with dynamic light scattering (DLS) and atomic force microscopy (AFM). Spherical micelles with a diameter of 70 nm in aqueous solution were obtained.
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Wang, S., Zhang, B., Ai, P. et al. Chemoenzymatic synthesis amphiphilic H-shaped copolymer and its self-assembly behavior. Sci. China Ser. B-Chem. 52, 2336–2341 (2009). https://doi.org/10.1007/s11426-009-0128-6
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DOI: https://doi.org/10.1007/s11426-009-0128-6