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Investigation of molecular interactions in the complex formation of tartaric acid derivatives with di(2-ethylhexyl) phosphoric acid

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Abstract

The molecular interactions in the complex formation of two tartaric acid derivatives with di(2-ethylhexyl) phosphoric acid are investigated. The complex formation with a 1:1 stoichiometry between tartaric acid derivatives and D2EHPA can be obtained through UV-Vis titration, NMR chemical shifts and molecular dynamic simulations. Furthermore, the differences of the two complexes on the binding constants and strength of hydrogen bonds can also be determined. Such research will ideally provide insight into ways of regulating the complex forming properties of tartaric acid derivatives for composing or synthesizing new chiral resolving agents.

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Authors and Affiliations

  1. State Key Laboratory of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing, 100084, China

    Bin Tan, Zheng Zhai, GuangSheng Luo & JiaDing Wang

Authors
  1. Bin Tan
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  2. Zheng Zhai
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  3. GuangSheng Luo
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  4. JiaDing Wang
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Corresponding author

Correspondence to GuangSheng Luo.

Additional information

Supported by the National Basic Research Program of China (Grant No. 2007CB714302) and the National Natural Science Foundation of China (Grant Nos. 20676066 & 20525622)

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Tan, B., Zhai, Z., Luo, G. et al. Investigation of molecular interactions in the complex formation of tartaric acid derivatives with di(2-ethylhexyl) phosphoric acid. Sci. China Ser. B-Chem. 51, 887–892 (2008). https://doi.org/10.1007/s11426-008-0066-8

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  • DOI: https://doi.org/10.1007/s11426-008-0066-8

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