Abstract
In a pH 3.6–5.0 HAc-NaAc buffer solution, when sodium tanshinon IIA silate (STSIIA) reacts with La(III) to form a chelate, the resonance Rayleigh scattering (RRS) intensity can be enhanced greatly and a new RRS spectrum will appear. The maximum RRS peak is located at 306 nm and the RRS intensity is proportional to the concentration of STSIIA in a certain range. The method is very sensitive and the detection limit for STSIIA (3σ/K) is 82.12 ng·mL−1. The optimum reaction conditions and the effect of coexisting substances have been investigated. A new, simple and fast method for the determination of STSIIA based on RRS method is developed. It can be applied to the determination of STSIIA in the synthesis samples and Nuoxinkang injection. Combined with infrared absorption and NMR spectra, the structure of the chelate and the reasons of RRS enhancement are also discussed.
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References
Liang Y, Yang Y M, Yuan S L. Progress of the pharmacological actions and clinical application for tanshinone IIA. Chinese Traditional and Herbal Drugs (in Chinese), 2000, 31(4): 304–306
Yuan C Q. The Development and Utilization of Natural Resources (in Chinese). Nanjing: Jiangsu Science and Technique Press, 2000. 12
Yan M. Determination of the tanshinone IIA in Xueyakang granule by colum chromatography-spectrophotometry. Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology (in Chinese), 1998, 4(9): 32–33
Han J, Liu J M, Gao Y M. Determination of the tanshinone IIA in Bailing granule by three-wavelength spectrophotometry. Shandong Pharmaceutical Industry (in Chinese), 1996, 15(4): 16–17
Sun W J, Meng H B, Gao H. Determination of the tanshinone IIA in Danshen by solid phase extraction-spectrophotometry. Chinese Journal of Pharmaceutical Analysis (in Chinese), 1996, 16(3): 199–200
Sun M C. Determination of the tanshinone IIA in Gengniankang granule by TLC-scanning method. Chinese Medical Report (in Chinese), 2003, 22(7): 478–479
Wang X H, Li Y L, Zhou L. Determination of the tanshinone IIA in Zhongfeng Huichun troche by TLC-scanning method. Northwest Pharmaceutical Journal (in Chinese), 2003, 18(2): 57
Wang M, Tang Z S, Ling X W. Determination of the tanshinone IIA in Fufang Dilong Blood Pressure Lowering Phill by HPLC method. Journal of Shanxi College of Traditional Chinese Medicine (in Chinese), 2002, 25(9): 47–48
Tu W S, Liang Z L, Liu Z H. Determination of the tanshinone IIA in Fufang Jinpu troche. China Pharmacy (in Chinese), 2003, 4(11): 689–690
Qian M B, Yang B J, Gu W H. Studies on efficacious constituents of Danshen. Acta Chimica Sinica (in Chinese), 1978, 36(3): 199–205
Chao J B, Cheng L, Zhang L W. Study on the complex process of tanshinone IIA with rare earth Eu3+, Tb3+, metal ions. Chinese Journal of Magnetical Resonance (in Chinese), 2001, 18(1): 67–71
Gao J Z, Yang W, Kang J W. Spectroscopic Chemistry of Lanthanide Complexes in Solution (in Chinese). Chengdu: University of Electronic Science and Technology of China Press, 1995, 197
Editorial Committee of Encyclopedia of China. The Encyclopedia of China (in Chinese), Biology II. Beijing: Encyclopedia of China Press, 1991. 1374
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Peng, J., Liu, S., Liu, Z. et al. Resonance Rayleigh scattering spectrum for the chelate of lanthanum(III) with sodium tanshinon IIA silate and its analytical application. SCI CHINA SER B 49, 423–429 (2006). https://doi.org/10.1007/s11426-006-2011-z
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DOI: https://doi.org/10.1007/s11426-006-2011-z