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Osteoarthritis as a Whole Joint Disease

  • HSS OSTEOARTHRITIS SYMPOSIUM: FRONTIERS IN OA
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References

  1. Blom AB, Brockbank SM, van Lent PL, Van Beuningen HM, Guerts J et al. Involvement of the Wnt signaling pathway in experimental and human osteoarthritis. Prominent role of Wnt-induced signaling protein 1. Arthritis Rheum 60: 501–12, 2009.

    Article  PubMed  CAS  Google Scholar 

  2. Clockaerts S, Bastiaansen-Jenniskens YM, Runhaar J, Van Osch GJ, Van Offel JF et al. The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review.Osteoarthritis Cartilage.18:876–82, 2010

    Article  PubMed  CAS  Google Scholar 

  3. Dieppe P, Cushnaghan J, Young P, Kirwan J. Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy. Ann Rheum Dis.52: 557–63, 1993

    Article  PubMed  CAS  Google Scholar 

  4. Douglas MJM, Hutchison JD, Sutherland AG. Anterior cruciate ligament integrity in osteoarthritis of the knee in patients undergoing total knee replacement. J Orthop Traumatol. 11: 149–154, 2010.

    Article  PubMed  CAS  Google Scholar 

  5. Englund M, Guermazi A, Gale D, Hunter DJ, Aliabadi P et al. Incidental meniscal findings on knee MRI in middle-aged and elderly persons. N Engl J Med 11;359(11):1108–15, 2008

    Google Scholar 

  6. Gobezie R, Kho A, Sarracino DA, Theornhill TS, Chase M et al. High abundance synovial fluid proteome: distinct profiles in health and osteoarthritis. Arthritis Res Ther 9: R36, 2007.

    Article  PubMed  Google Scholar 

  7. Hill CL, Hunter DJ, Niu J, Clancy M,Guermazi A et al. Synovitis detected on magnetic resonance imaging and its relation to pain and cartilage loss in knee osteoarthritis. Ann Rheum Dis 66:1599–603, 2007.

    Article  PubMed  Google Scholar 

  8. Ishijima M, Watari T, Naito K, Kaneko H, Futami I et al. Relationships between biomarkers of cartilage, bone, synovial metabolism and knee pain provide insights into the origins of pain in early knee osteoarthritis. Arthritis Res Ther 14:13:R22, 2011

    Google Scholar 

  9. Klein-Wieringa IR, Kloppenburg M, Bastiaansen-Jenniskens YM, Yusuf E, Kwekkeboom JC et al. Extended report: the infrapatellar fat pad of patients with osteoarthritis has an inflammatory phenotype. Ann Rheum Dis 70:851–7, 2011

    Article  PubMed  CAS  Google Scholar 

  10. Kothari A, Guermazi A, Chmiel JS, Dunlop D, Song J et al. Within-subregion relationship between bone marrow lesions and subsequent cartilage loss in knee osteoarthritis. Arthritis Care Res 62: 198–203, 2010.

    Google Scholar 

  11. Lo GH, Hunter DJ, Nevitt M, Lynch J, McAlindon TE; OAI Investigators Group. Strong association of MRI meniscal derangement and bone marrow lesions in knee osteoarthritis: data from the osteoarthritis initiative. Osteoarthritis Cartilage 17:743–7, 2009.

    Article  PubMed  CAS  Google Scholar 

  12. Lodewyckx L, Lories RJ. Wnt signaling in osteoarthritis and osteoporosis: what is the biological significance for the clinician. Curr Rheumatol Rep. 11: 23–30, 2009.

    Article  PubMed  CAS  Google Scholar 

  13. McCarthy C, Cushnaghan J, Dieppe P. The predictive role of scintigraphy in radiographic osteoarthritis of the hand. Osteoarthritis Cartilage 2:25–8, 1994

    Article  PubMed  CAS  Google Scholar 

  14. Poole AR Cartilage in health and disease. In: Arthritis and Allied Conditions. A Textbook of Rheumatology, 15th Edition. Edited by W. Koopman, L.Moreland, Lippincott, Williams and Wilkins, Philadelphia, pp. 223–269, 2004.

  15. Poole AR, Guilak F, Abramson SB. Etiopathogenesis of osteoarthritis. In:Osteoarthritis. Diagnosis and Medical/Surgical Management, 4th Edition. Edited by RW Moskowitz, RD Altman, MC Hochberg, JA Buckwalter, VM.Goldberg. Lippincott Williams & Wilkins, Philadelphia, pp.27-49, 2007.

  16. Roemer FW, Guermazi A, Hunter DJ, Niu J, Zhang Y, Englund M et al. The association of meniscal damage with joint effusion in persons without radiographic osteoarthritis: the Framingham and MOST osteoarthritis studies. Osteoarthritis Cartilage 17:748–53, 2008.

    Article  PubMed  Google Scholar 

  17. Tan AL, Grainger AJ, Tanner SF, Shelley DM, Pease C et al. High-resolution magnetic resonance imaging for the assessment of hand osteoarthritis. Arthritis Rheum 52: 2355–65, 2005.

    Article  PubMed  Google Scholar 

  18. Tan AL, Toumi H, Benjamin M, Grainger AJ, Tanner SF et al. Combined high-resolution imaging and histological examination to explore the role of ligaments and tendons in the phenotypic expression of early hand osteoarthritis. Ann Rheum Dis 65: 1267–72, 2006.

    Article  PubMed  CAS  Google Scholar 

  19. Wong M, Siegrist M, Goodwin K. Cyclic tensile strain and cyclic hydrostatic pressure differentially regulate expression of hypertrophic markers in primary chondrocytes. Bone 33: 685–93, 2003.

    Article  PubMed  CAS  Google Scholar 

  20. Yavorskyy A, Hernandez-Santana A, McCarthy G, McMahon G. Detection of calcium phosphate crystals in the joint fluid of patients with osteoarthritis-analytical approaches and challenges. Analyst 133: 302–18, 2008.

    Article  PubMed  CAS  Google Scholar 

  21. Zhu M, Tang D, Hao S, Chen M, Xie C, et al. Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice. J Bone Min Res 24: 12–21, 2009.

    Article  CAS  Google Scholar 

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Correspondence to A. Robin Poole PhD, DSc.

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Poole, A.R. Osteoarthritis as a Whole Joint Disease. HSS Jrnl 8, 4–6 (2012). https://doi.org/10.1007/s11420-011-9248-6

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  • DOI: https://doi.org/10.1007/s11420-011-9248-6

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