Skip to main content
SpringerLink
Log in

Surface adsorption of cannabinoids in LC–MS/MS applications

  • Letter to the Editor
  • Published:
Forensic Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

References

  1. Chu MHC, Drummer OH (2002) Determination of ∆ 9-THC in whole blood using gas chromatography-mass spectrometry. J Anal Toxicol 26:575–581. https://doi.org/10.1093/jat/26.8.575

    Article  CAS  PubMed  Google Scholar 

  2. Roth KDW, Siegel NA, Johnson RW Jr, Litauszki L, Salvati L Jr, Harrington CA, Wray LK (1996) Investigation of the effects of solution composition and container material type on the loss of 11-nor ∆ 9-THC-9-carboxylic acid. J Anal Toxicol 20:291–300. https://doi.org/10.1093/jat/20.5.291

    Article  CAS  PubMed  Google Scholar 

  3. Dugan S, Bogema S, Schwartz RW, Lappas NT (1994) Stability of drugs of abuse in urine samples stored at − 20 °C. J Anal Toxicol 18:391–396. https://doi.org/10.1093/jat/18.7.391

    Article  CAS  PubMed  Google Scholar 

  4. Blanc JA, Manneh VA, Ernst R, Berger DE, de Keczer SA, Chase C, Centofanti JM, DeLizza AJ (1993) Adsorption losses from urine-based cannabinoid calibrators during routine use. Clin Chem 39:1705–1712 (PMID:8394791)

    CAS  PubMed  Google Scholar 

  5. Bond GD, Chand PC, Walia AS, Liu RH, Ogden SD (1990) Observation of reduced concentration of ∆ 9-THC-carboxylic acid in urine specimen containers using internal barcode labels. J Anal Toxicol 14:389–390. https://doi.org/10.1093/jat/14.6.389

    Article  CAS  PubMed  Google Scholar 

  6. Dextraze P, Griffiths WC, Camara P, Audette L, Rosner M (1989) Comparison of fluorescence polarization immunoassay, enzyme immunoassay, and thin-layer chromatography for urine cannabinoid screening. Effects of analyte adsorption and vigorous mixing of specimen on detectability. Ann Clin Lab Sci 19:133–138 (PMID: 2546480)

    CAS  PubMed  Google Scholar 

  7. Christophersen AS (1986) Tetrahydrocannabinol stability in whole blood: plastic versus glass containers. J Anal Toxicol 10:129–131. https://doi.org/10.1093/jat/10.4.129

    Article  CAS  PubMed  Google Scholar 

  8. Fenimore DC, Davis CM, Whitford JH, Harrington CA (1976) Vapor phase silylation of laboratory glassware. Anal Chem 48:2289–2290. https://doi.org/10.1021/ac50008a065

    Article  CAS  Google Scholar 

  9. Garrett ER, Hunt CA (1974) Physicochemical properties, solubility, and protein binding of ∆ 9-tetrahydrocannabinol. J Pharm Sci 63:1056–1064. https://doi.org/10.1002/jps.2600630705

    Article  CAS  PubMed  Google Scholar 

  10. Jamerson MH, McCue JJ, Klette KL (2005) Urine pH, container composition, and exposure time influence adsorptive loss of 11-nor-∆ 9-tetrahydrocannabinol-9-carboxylic acid. J Anal Toxicol 29:627–631. https://doi.org/10.1093/jat/29.7.627

    Article  CAS  PubMed  Google Scholar 

  11. Welsh ER, Snyder JJ, Klette KL (2009) Stabilization of urinary THC solutions with a simple non-ionic surfactant. J Anal Toxicol 33:51–55. https://doi.org/10.1093/jat/33.1.51

    Article  CAS  PubMed  Google Scholar 

  12. Joerm WA (1987) Detection of past and recurrent marijuana use by a modified GC/MS procedure. J Anal Toxicol 11:49–52. https://doi.org/10.1093/jat/11.2.49

    Article  Google Scholar 

  13. Joern WA (1992) Surface adsorption of the urinary marijuana carboxy metabolite: the problem and a partial solution. J Anal Toxicol 16:401. https://doi.org/10.1093/jat/16.6.401

    Article  CAS  PubMed  Google Scholar 

  14. United Chemical Technologies (2009) Delta 9-THC (parent), delta 9-hydroxy THC, carboxy-delta 9-THC in whole blood for GC/MS confirmation using: 200 mg clean screen® extraction column. United Chemicals Technologies, Bristol

    Google Scholar 

  15. Jamey C, Szwarc E, Tracqui A, Ludes B (2008) Determination of cannabinoids in whole blood by UPLC-MS-MS. J Anal Toxicol 32:349–354. https://doi.org/10.1093/jat/32.5.349

    Article  CAS  PubMed  Google Scholar 

  16. Coulter C, Miller E, Crompton K, Moore C (2008) Tetrahydrocannabinol and two of its metabolites in whole blood using liquid chromatography-tandem mass spectrometry. J Anal Toxicol 32:653–658. https://doi.org/10.1093/jat/32.8.653

    Article  CAS  PubMed  Google Scholar 

  17. Øiestad EL, Johansen U, Øiestad ÅML, Christophersen AS (2011) Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry. J Anal Toxicol 35:280–293. https://doi.org/10.1093/anatox/35.5.280

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Georgia Bureau of Investigation Division of Forensic Sciences, P.O. Box 370808, Decatur, GA, USA

    Jon B. Stephenson, Denise N. Carter & Mario Richardson

Authors
  1. Jon B. Stephenson
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Denise N. Carter
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Mario Richardson
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jon B. Stephenson.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Stephenson, J.B., Carter, D.N. & Richardson, M. Surface adsorption of cannabinoids in LC–MS/MS applications. Forensic Toxicol 38, 292–296 (2020). https://doi.org/10.1007/s11419-019-00505-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11419-019-00505-x

Search

Navigation