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Table 2 Effect of pentobarbital on specific [3H]CP55940 binding to the synaptic membrane from mice brains

From: 9-Tetrahydrocannabinol, a major marijuana component, enhances the anesthetic effect of pentobarbital through the CB1 receptor

Compound

Specific [3H]CP55940 binding

(pmol/mg protein)

Control

0.055 ± 0.002

Pentobarbital 1 mM

0.050 ± 0.003 N.S.

  1. Pentobarbital 1 mM was added to the reaction mixture
  2. NS No significant difference from control binding