Journal of Natural Medicines

, Volume 72, Issue 2, pp 557–562 | Cite as

The active glycosides from Urtica fissa rhizome decoction

  • Mengyue Wang
  • Ying Zhang
  • Hao Zhang
  • Xiaoru Feng
  • Xiaobo LiEmail author


Using bioassay guided fractionation, 16 glycosides, including two new compounds (1 and 2), were isolated from the anticomplement and anti-inflammatory portion of an Urtica fissa rhizome decoction used for arthritis. Several compounds were found to possess significant anticomplement and anti-inflammatory activities. This study revealed that glycosides played an important role in the therapeutic effects of Urtica fissa rhizome.


Urtica fissa Decoction Glycoside Anticomplement Anti-inflammatory 



This study was financially supported by a grant of the National Natural Science Fund of China (No. 81374067). The authors would like to thank Dr. Bona Dai of the Instrumental Analysis Center of Shanghai Jiao Tong University for NMR measurement.

Compliance with ethical standards

Conflict of interest

The authors declare that there is no any conflict of interest to disclose.

Supplementary material

11418_2018_1172_MOESM1_ESM.pdf (1.6 mb)
Supplementary material 1 (PDF 1626 kb)


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Copyright information

© The Japanese Society of Pharmacognosy and Springer Japan KK, part of Springer Nature 2018

Authors and Affiliations

  • Mengyue Wang
    • 1
  • Ying Zhang
    • 1
  • Hao Zhang
    • 1
  • Xiaoru Feng
    • 1
  • Xiaobo Li
    • 1
    Email author
  1. 1.School of PharmacyShanghai Jiao Tong UniversityShanghaiPeople’s Republic of China

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