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Chemical structures of constituents from the flowers of Osmanthus fragrans var. aurantiacus

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Abstract

Three new megastigmane glycosides named floraosmanosides I–III and a new γ-decalactone named floraosmanolactone I together with 16 known constituents were isolated from the flowers of Osmanthus fragrans var. aurantiacus cultivated in Guangxi Zhuang Autonomous Region, China. The chemical structures of the new compounds were elucidated on the basis of chemical and physicochemical evidence. Among them, ligustroside and (+)-pinoresinol significantly inhibited nitric oxide production in lipopolysaccharide-activated RAW264.7 macrophages.

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Acknowledgments

This work was supported in part by a Ministry of Education, Culture, Sports, Science and Technology (MEXT)-Supported Program for the Strategic Research Foundation at Private Universities and by JSPS KAKENHI Grant Number 26460135.

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Authors and Affiliations

  1. Department of Pharmacognosy, Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, 607-8412, Japan

    Seikou Nakamura, Bin Xu, Takahiro Matsumoto, Tomoe Ohta, Katsuyoshi Fujimoto, Keiko Ogawa, Masashi Fukaya, Shiori Miyake, Masayuki Yoshikawa & Hisashi Matsuda

  2. Key Laboratory of Crop Ecophysiology and Farming System in Southwest China, Ministry of Agriculture, Sichuan Agricultural University, Chengdu, 611130, People’s Republic of China

    Jiang Liu

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  1. Jiang Liu
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  2. Seikou Nakamura
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  3. Bin Xu
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  6. Katsuyoshi Fujimoto
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Correspondence to Hisashi Matsuda.

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Liu, J., Nakamura, S., Xu, B. et al. Chemical structures of constituents from the flowers of Osmanthus fragrans var. aurantiacus . J Nat Med 69, 135–141 (2015). https://doi.org/10.1007/s11418-014-0869-1

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  • DOI: https://doi.org/10.1007/s11418-014-0869-1

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