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Hypelodins A and B, polyprenylated benzophenones from Hypericum elodeoides

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Abstract

Two new polyprenylated benzophenones, hypelodins A (1) and B (2), were isolated from the aerial parts of the Chinese medicinal plant Hyperium elodeoides (Choisy). Their structures were elucidated on the basis of spectroscopic evidence. Hypelodin A (1) is a polyprenylated benzophenone having a tetrahydropyrane ring with three prenyl groups and one 4-methyl-1,3-pentadiene moiety, while hypelodin B (2) has a cage-like structure with a 6/6/5/7/6/5 hexacyclic ring system.

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Authors and Affiliations

  1. Graduate School of Pharmaceutical Sciences, The University of Tokushima, 1-78-1 Shomachi, Tokushima, 770-8505, Japan

    Chika Hashida, Naonobu Tanaka, Yoshihisa Takaishi & Yoshiki Kashiwada

  2. Department of Clinical Pharmacy, Tokushima University Hospital, 2-50-1 Kuramoto, Tokushima, 770-8503, Japan

    Kazuyoshi Kawazoe

  3. Faculty of Pharmaceutical Sciences, Sojo University, 4-22-1 Ikeda, Kumamoto, 862-0082, Japan

    Kotaro Murakami

  4. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, 650201, People’s Republic of China

    Han-Dong Sun

Authors
  1. Chika Hashida
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  2. Naonobu Tanaka
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  3. Kazuyoshi Kawazoe
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  4. Kotaro Murakami
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  5. Han-Dong Sun
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  6. Yoshihisa Takaishi
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  7. Yoshiki Kashiwada
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Corresponding author

Correspondence to Yoshiki Kashiwada.

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Hashida, C., Tanaka, N., Kawazoe, K. et al. Hypelodins A and B, polyprenylated benzophenones from Hypericum elodeoides . J Nat Med 68, 737–742 (2014). https://doi.org/10.1007/s11418-014-0853-9

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  • DOI: https://doi.org/10.1007/s11418-014-0853-9

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