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Four new compounds from Imperata cylindrica

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Abstract

Four new compounds, impecylone (1), deacetylimpecyloside (2), seguinoside K 4-methylether (3) and impecylenolide (4), were isolated from Imperata cylindrica along with two known compounds, impecyloside (5) and seguinoside K (6). Their structures were elucidated mainly by spectroscopic analyses including 1D- and 2D-NMR techniques, and the absolute configuration of 1 was confirmed by X-ray diffraction analysis. In calcium assay, the result indicated that compounds 1, 2, 4 and 5 cannot obviously inhibit the calcium peak value compared with the negative control, and suggested that the four compounds could not have anti-inflammatory activity.

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Acknowledgments

The project was financially supported by the Shanghai Science and Technology Development Foundation (10DZ1970200) and the Program for Changjiang Scholars and Innovative Research Team in University (IRT1071).

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Authors and Affiliations

  1. Department of Pharmacognosy, China Pharmaceutical University, Nanjing, 210038, People’s Republic of China

    Xuan Liu & Zheng-Tao Wang

  2. Shanghai R&D Center for Standardization of Chinese Medicines, 199 Guo Shoujing Road, Zhangjiang Hi-Tech Park, Shanghai, 201203, People’s Republic of China

    Bin-Feng Zhang, Li Yang, Gui-Xin Chou & Zheng-Tao Wang

  3. Key Laboratory of Standardization of Chinese Medicines, Ministry of Education, Institute of Chinese Materia Medica of SUTCM, Shanghai University of Traditional Chinese Medicine, Cai Lun Road 1200, Zhangjiang, Shanghai, 201203, People’s Republic of China

    Bin-Feng Zhang, Li Yang, Gui-Xin Chou & Zheng-Tao Wang

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  1. Xuan Liu
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  2. Bin-Feng Zhang
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  3. Li Yang
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  4. Gui-Xin Chou
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Correspondence to Zheng-Tao Wang.

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Liu, X., Zhang, BF., Yang, L. et al. Four new compounds from Imperata cylindrica . J Nat Med 68, 295–301 (2014). https://doi.org/10.1007/s11418-013-0793-9

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  • DOI: https://doi.org/10.1007/s11418-013-0793-9

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