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Constituents of Caryopteris incana and their antibacterial activity

Journal of Natural Medicines volume 68, pages 231–235 (2014)Cite this article

Abstract

Two new compounds named caryocanolide (1), and caryocanoside A (2), together with nine known compounds (3–11) were isolated from the whole plant of Caryopteris incana. These structures were determined mainly on the basis of 2D nuclear magnetic resonance and high resolution fast atom bombardment mass spectroscopy data. Furthermore, the isolated compounds (1, 2, 4–11) were tested for their antibacterial activity. Compound 1 exhibited moderate antimicrobial activity against Bacillus subtilis with a minimum inhibitory concentration value of 35.7 μM.

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Authors and Affiliations

  1. Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-Cho, Tokushima, 770-8514, Japan

    Kazuko Yoshikawa, Akinori Harada, Kanako Iseki & Toshihiro Hashimoto

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  1. Kazuko Yoshikawa
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  2. Akinori Harada
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  3. Kanako Iseki
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  4. Toshihiro Hashimoto
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Correspondence to Kazuko Yoshikawa.

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Yoshikawa, K., Harada, A., Iseki, K. et al. Constituents of Caryopteris incana and their antibacterial activity. J Nat Med 68, 231–235 (2014). https://doi.org/10.1007/s11418-013-0785-9

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  • DOI: https://doi.org/10.1007/s11418-013-0785-9

Keywords

  • Caryopteris incana
  • Verbenaceae
  • Clerodane diterpenoid
  • Iridoid glycoside
  • Caryocanolide
  • Caryocanoside A
  • Phenylethanoid glycoside
  • Antibacterial activity