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Journal of Natural Medicines

, Volume 67, Issue 1, pp 228–233 | Cite as

Phenylethanoid and flavone glycosides from Ruellia tuberosa L.

  • Chiobouaphong Phakeovilay
  • Wannaporn Disadee
  • Poolsak Sahakitpichan
  • Somkit Sitthimonchai
  • Prasat Kittakoop
  • Somsak Ruchirawat
  • Tripetch KanchanapoomEmail author
Note

Abstract

A new phenylethanoid glycoside, isocassifolioside (8), and two new flavone glycosides, hispidulin 7-O-α-l-rhamnopyranosyl-(1′″ → 2″)-O-β-d-glucuronopyranoside (11) and pectolinaringenin 7-O-α-l-rhamnopyranosyl-(1′″ → 2″)-O-β-d-glucuronopyranoside (12) were isolated from the aerial portions of Ruellia tuberosa L., together with verbascoside (1), isoverbascoside (2), nuomioside (3), isonuomioside (4), forsythoside B (5), paucifloside (6), cassifolioside (7), hispidulin 7-O-β-d-glucuronopyranoside (9) and comanthoside B (10). The structure elucidations were based on analyses of chemical and spectroscopic data including 1D- and 2D-NMR. The isolated compounds 112 exhibited radical scavenging activity using ORAC assay.

Keywords

Ruellia tuberosa Acanthaceae Flavone glycoside Phenylethanoid glycoside Antioxidant activity 

Notes

Acknowledgments

This study was financially supported by The Thailand Research Fund (Grant No. DBG5480007) and Chulabhorn Research Institute. Also, C.P. would like to thank Thailand International Development Cooperation Agency (TICA) for providing financial support during study in Thailand.

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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2012

Authors and Affiliations

  • Chiobouaphong Phakeovilay
    • 1
  • Wannaporn Disadee
    • 1
    • 2
  • Poolsak Sahakitpichan
    • 1
    • 2
  • Somkit Sitthimonchai
    • 2
  • Prasat Kittakoop
    • 1
    • 2
  • Somsak Ruchirawat
    • 1
    • 2
  • Tripetch Kanchanapoom
    • 2
    • 3
    Email author
  1. 1.Chemial Biology ProgramChulabhorn Graduate InstituteBangkokThailand
  2. 2.Chulabhorn Research InstituteBangkokThailand
  3. 3.Faculty of Pharmaceutical SciencesKhon Kaen UniversityKhon KaenThailand

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