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Constituents from leaves of Apocynum venetum L.

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Abstract

An analysis using HPLC–MS revealed that an extract from dried leaves of Apocynum venetum L. contained more than 15 kinds of phenolic constituents. Two malonated flavonol glycosides were further isolated, and their structures were determined to be quercetin 3-O-(6′′-O-malonyl)-β-d-glucoside (1) and quercetin 3-O-(6′′-O-malonyl)-β-d-galactoside (2) by NMR spectroscopic analysis. This is the first report describing the isolation of these malonated flavonol glycosides from A. venetum L. Both glycosides showed strong scavenging activity against 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical.

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Acknowledgment

We thank Prof. Hiromitsu Takayama (Chiba University) for his measurement of the 1H and 13C NMR spectra.

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  1. Tokiwa Phytochemical Co., Ltd., 158 Kinoko, Sakura, Chiba, 285-0801, Japan

    Kazuaki Kamata, Shujiro Seo & Jun-ichiro Nakajima

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  1. Kazuaki Kamata
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  2. Shujiro Seo
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  3. Jun-ichiro Nakajima
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Correspondence to Jun-ichiro Nakajima.

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Kamata, K., Seo, S. & Nakajima, Ji. Constituents from leaves of Apocynum venetum L.. J Nat Med 62, 160–163 (2008). https://doi.org/10.1007/s11418-007-0202-3

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  • DOI: https://doi.org/10.1007/s11418-007-0202-3

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