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Lignan glycosides and flavonoids from Saraca asoca with antioxidant activity


Five lignan glycosides, lyoniside, nudiposide, 5-methoxy-9-β-xylopyranosyl-(−)-isolariciresinol, icariside E3, and schizandriside, and three flavonoids, (−)-epicatechin, epiafzelechin-(4β→8)-epicatechin and procyanidin B2, together with β-sitosterol glucoside, were isolated from a methyl alcohol (MeOH) extract of Saraca asoca dried bark. Their structures were determined by 1D and 2D nuclear magnetic resonance (NMR) and mass spectroscopic analysis. Antioxidant activities were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay.

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This work was partly supported by a Grant-in-Aid from Tokyo Biochemical Research Foundation (TBRF), Japan.

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Correspondence to Masami Ishibashi.

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Sadhu, S.K., Khatun, A., Phattanawasin, P. et al. Lignan glycosides and flavonoids from Saraca asoca with antioxidant activity. J Nat Med 61, 480–482 (2007).

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  • Saraca asoca
  • Caesalpiniaceae
  • Lignan glycoside
  • Flavonoid
  • Antioxidant activity