Skip to main content
Log in

A new ceramide from Ramaria botrytis (Pers.) Ricken

  • Note
  • Published:
Journal of Natural Medicines Aims and scope Submit manuscript

Abstract

A new ceramide, (2S,2′R,3R,4E,8E)-N-2′-hydroxyoctadecanoyl-2-amino-9-methyl-4,8-heptadecadiene-1,3-diol (1), was isolated together with four known sterols, 5α,6α-epoxy-3β-hydroxy-(22E)-ergosta-8(14),22-dien-7-one (2), ergosterol peroxide (3), cerevisterol (4) and 9α-hydroxycerevisterol (5), from the fruiting bodies of Ramaria botrytis (Pers.) Ricken (Ramariaceae). The structure of the new compound was elucidated based on spectral data.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Scheme 1
Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Wasser SP, Weis AL (1999) Therapeutic effect of substances occurring in higher basidiomycetes mushrooms. A modern perspective. Crit Rev Immunol 19:65–96

    PubMed  Google Scholar 

  2. Borthers AT, Stern JS, Hackman RM, Keen CL, Gershwin ME (1999) Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med 221:281–293

    Article  Google Scholar 

  3. Park W (1982) Chemical components of mushrooms. I. Survey of amino acids by TLC. Saengyak Hakhoechi 13:43–46

    Google Scholar 

  4. Prostenik M, Castek A, Cosovic C, Gospocic L, Jandric Z, Kljaic K, Ondrusek V (1983) The patterns of the constituent fatty acids of glycerophospholipids in mushrooms. Lipids of higher fungi. Exp Mycol 7:74–81

    Article  Google Scholar 

  5. Yaoita Y, Danbara K, Kikuchi M (2005) Two new aromatic compounds from Hericium erinaceum (Bull.: Fr) Pers. Chem Pharm Bull 53:1202–1203

  6. Aiello A, Fattorusso E, Magno S, Mayol L, Menna M (1990) Isolation of two novel 5α,6α-epoxy-7-ketosterols from the encrusting demospongia Oscarella lobularis. J Nat Prod 53:487–491

    Google Scholar 

  7. Yaoita Y, Amemiya K, Ohnuma H, Furumura K, Masaki A, Matsuki T, Kikuchi M (1998) Sterol constituents from five edible mushrooms. Chem Pharm Bull 46:944–950

    Google Scholar 

  8. Chebaane K, Guyot M (1986) Occurrence of erythro-docosasphinga-4,8-dienine, as an ester, in Anemonia sulcata. Tetrahedron Lett 27:1495–1496

    Google Scholar 

  9. Shin J, Seo Y (1995) Isolation of new ceramides from the gorgonian Acabaria undulate. J Nat Prod 58:948–953

    Article  Google Scholar 

  10. Couperus PA, Clague ADH, van Dongen JPCM (1976) 13C chemical shifts of some model olefins. Org Magn Res 8:426–431

    Article  Google Scholar 

  11. Yaoita Y, Kohata R, Kakuda R, Machida K, Kikuchi M (2002) Ceramide constituents from five mushrooms. Chem Pharm Bull 50:681–684

    Article  PubMed  Google Scholar 

  12. Liu J, Hu L, Dong Z (2003) A glucosylceramide with a novel ceramide and three novel ceramides from the basidiomycete Cortinarius umidicola. Lipids 38:669–675

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We are grateful to Mr. S. Sato and Mr. T. Matsuki of this university for measuring the masses and NMR spectra.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Masao Kikuchi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Yaoita, Y., Satoh, Y. & Kikuchi, M. A new ceramide from Ramaria botrytis (Pers.) Ricken. J Nat Med 61, 205–207 (2007). https://doi.org/10.1007/s11418-006-0121-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11418-006-0121-8

Keywords

Navigation