Journal of Natural Medicines

, Volume 60, Issue 3, pp 206–209 | Cite as

A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV.

  • Yuji Narukawa
  • Keiichiro Hatano
  • Tadahiro Takeda
Original Paper


A new diterpenoid with a rearranged neoclerodane skeleton, spiroleucantholide (compound “S1”), along with four known diterpenoids—salvifaricin (compound “S2”), isosalvipuberulin (compound “S3”), salvileucantholide (compound “S4”), and salviandulin E (compound “S5”)—was isolated from the aerial parts of Salvia leucantha CAV.. The structures were established by spectroscopic methods, including the X-ray analysis of spiroleucantholide (S1).


Salvia leucantha CAV. Labiatae Neoclerodane-related compounds Spiroleucantholide 


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Copyright information

© The Japanese Society of Pharmacognosy and Springer 2006

Authors and Affiliations

  • Yuji Narukawa
    • 1
  • Keiichiro Hatano
    • 2
  • Tadahiro Takeda
    • 1
  1. 1.Kyoritsu University of PharmacyTokyo 105-8512Japan
  2. 2.Graduate School of Pharmaceutical ScienceNagoya City UniversityNagoya 467-8603Japan

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