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Tropane alkaloids from Erythroxylum emarginatum

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Abstract

A tropane alkaloid, anhydroecgonine methyl ester N-oxide (2), was isolated for the first time as a naturally occurring compound, with anhydroecgonine methyl ester (1) from the bark of Erythroxylum emarginatum. Compound 1 was also isolated from the twigs. Their structures were elucidated mainly by spectroscopic methods.

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Authors and Affiliations

  1. Natural Medicinal Chemistry, Kobe Pharmaceutical University, 4-19-1, Motoyamakita-machi, Higashinada-ku, Kobe, 658-8558, Japan

    Yumi Nishiyama, Masataka Moriyasu, Momoyo Ichimaru, Maki Sonoda, Kinuko Iwasa & Atsushi Kato

  2. Department of Clinical Pharmacology, Kenyatta National Hospital, University of Nairobi, P.O. Box 19676, Nairobi, Kenya

    Francis D. Juma

  3. Department of Botany, University of Nairobi, P.O. Box 30197, Nairobi, Kenya

    Simon G. Mathenge & Patrick B. Chalo Mutiso

Authors
  1. Yumi Nishiyama
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  2. Masataka Moriyasu
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  3. Momoyo Ichimaru
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  4. Maki Sonoda
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  5. Kinuko Iwasa
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  6. Atsushi Kato
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  7. Francis D. Juma
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  8. Simon G. Mathenge
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  9. Patrick B. Chalo Mutiso
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Correspondence to Yumi Nishiyama.

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Nishiyama, Y., Moriyasu, M., Ichimaru, M. et al. Tropane alkaloids from Erythroxylum emarginatum . J Nat Med 61, 56–58 (2007). https://doi.org/10.1007/s11418-006-0018-6

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  • DOI: https://doi.org/10.1007/s11418-006-0018-6

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