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AGE

, 38:10 | Cite as

Heterogeneity in resistance training-induced muscle strength and mass responses in men and women of different ages

  • Juha P. Ahtiainen
  • Simon Walker
  • Heikki Peltonen
  • Jarkko Holviala
  • Elina Sillanpää
  • Laura Karavirta
  • Janne Sallinen
  • Jussi Mikkola
  • Heli Valkeinen
  • Antti Mero
  • Juha J. Hulmi
  • Keijo Häkkinen
Article

Abstract

Physical activity recommendations for public health include typically muscle-strengthening activities for a minimum of 2 days a week. The range of inter-individual variation in responses to resistance training (RT) aiming to improve health and well-being requires to be investigated. The purpose of this study was to quantify high and low responders for RT-induced changes in muscle size and strength and to examine possible effects of age and sex on these responses. Previously collected data of untrained healthy men and women (age 19 to 78 years, n = 287 with 72 controls) were pooled for the present study. Muscle size and strength changed during RT are 4.8 ± 6.1 % (range from −11 to 30 %) and 21.1 ± 11.5 % (range from −8 to 60 %) compared to pre-RT, respectively. Age and sex did not affect to the RT responses. Fourteen percent and 12 % of the subjects were defined as high responders (>1 standard deviation (SD) from the group mean) for the RT-induced changes in muscle size and strength, respectively. When taking into account the results of non-training controls (upper 95 % CI), 29 and 7 % of the subjects were defined as low responders for the RT-induced changes in muscle size and strength, respectively. The muscle size and strength responses varied extensively between the subjects regardless of subject’s age and sex. Whether these changes are associated with, e.g., functional capacity and metabolic health improvements due to RT requires further studies.

Keywords

Individual variation Muscle hypertrophy Responders Aging 

Notes

Acknowledgments

Studies included in the present investigation were funded by the following foundations: The Finnish Ministry of Culture and Education; Finnish Cultural Foundation; Ellen and Artturi Nyyssönen Foundation, Finland; Polar Electro Oy; Juho Vainio Foundation, Finland; Central Finland Health Care District, Jyväskylä, Finland; Sport Institute Foundation, Finland; Yrjö Jahnsson Foundation, Finland; and National Doctoral Programme of Musculoskeletal Disorders and Biomaterials, Finland.

Compliance with ethical standards

Subjects were carefully informed about the design of the study with special information on possible risks and benefits both verbally and in writing, and they signed a written consent form before participation in the study. The studies were conducted according to the Declaration of Helsinki and were approved by the Ethics Committee of the University of Jyväskylä, Finland, and/or by the Ethics Committee of the Central Finland Health Care District.

Conflict of interest

The authors declare that they have no competing interests.

Supplementary material

11357_2015_9870_MOESM1_ESM.pdf (642 kb)
Supporting information 1 (PDF 641 kb)
11357_2015_9870_MOESM2_ESM.doc (19 kb)
Supporting information 2 (DOC 19.4 kb)
11357_2015_9870_MOESM3_ESM.pdf (20 kb)
Supporting information 3 (PDF 20 kb)

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Copyright information

© American Aging Association 2016

Authors and Affiliations

  • Juha P. Ahtiainen
    • 1
  • Simon Walker
    • 1
  • Heikki Peltonen
    • 1
  • Jarkko Holviala
    • 1
  • Elina Sillanpää
    • 2
  • Laura Karavirta
    • 1
  • Janne Sallinen
    • 1
  • Jussi Mikkola
    • 3
  • Heli Valkeinen
    • 4
  • Antti Mero
    • 1
  • Juha J. Hulmi
    • 1
  • Keijo Häkkinen
    • 1
  1. 1.Department of Biology of Physical ActivityUniversity of JyväskyläJyvaskylaFinland
  2. 2.Gerontology Research Center, Department of Health SciencesUniversity of JyväskyläJyvaskylaFinland
  3. 3.PhysiologyResearch Institute for Olympic SportsJyväskyläFinland
  4. 4.Department of WelfareNational Institute for Health and Welfare (THL)HelsinkiFinland

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