Abstract
Clioquinol (CLQ) is one of the most toxic halogenated neurodegenerative drugs, and its synaptic plasticity effect directly affects human health and the environment. Cupric oxide (CuO) is an ideal electrocatalyst owing to its earth-abundance, non-toxic nature, and cost-effectiveness. Since phenolate oxygen and pyridine nitrogen in CLQ act as an electron donor and pave the way for detection with Cu2+ ions in the CuO. Designing the architecture of CuO with a multi-walled carbon nanotube (MWCNT) is a sensible strategy to improve the electrochemical activity of the developed sensor. Inspired by the bio-synthesis and green processing, we have demonstrated the in-situ synthesis of CuO nanosphere-decorated MWCNT by Chenopodium album leaf extract through a sonochemical approach and explored its electrochemical sensing performance toward CLQ. The physical comprehensive characterization of prepared nanocomposite was investigated by various microscopic and spectroscopic techniques. For comparison studies, the CuO nanosphere was prepared by the same preparation process without MWCNT. Based on the physical characterization outcomes, the morphological nature of CuO was observed to be a sphere-like structure, which was decorated on the MWCNT with an average crystallite size of 16 nm (± 1 nm). Based on the electrochemical studies, the fabricated nanocomposite exhibits a wider linear range of 0.025–1375 μM, with a minimum detection limit of 4.59 nM L–1 toward CLQ. The viability examination on the biological matrix obtained considerable spike recoveries.
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Acknowledgements
The authors express sincere gratitude to Professor C.Y. Lee and his research team at the Department of Mechanical Engineering and Professor Sheng Tung Huang and his research team at the Department of Chemical Engineering, National Taipei University of Technology, for providing technical support. The authors acknowledged the management of Bishop Heber College (Autonomous), Tiruchirappalli -620 017, Tamil Nadu, India for the constant encouragement and facilities rendered by means of Material Chemistry Lab, PG and Research Department of Chemistry and DST-FIST Instrumentation Centre (HAIF) for Scientific Instrumentation.
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This work was supported by the Ministry of Science and Technology (MOST), Taiwan, under contract number MOST 111–2628-E-027–004-MY3.
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Sabarison Pandiyarajan: study’s conception, design, and first draft of the manuscript written.
Gurunathan Velayutham: material design and data curation.
Ai-Ho Liao: resource and formal analysis.
Shobana Sebastin Mary Manickaraj: software handle, data curation, and formal analysis.
Balaji Ramachandran: data curation and formal analysis.
Kuo-Yu Lee: resource and formal analysis.
Ho-Chiao Chuang: resource, supervision, formal analysis, and fund acquisition.
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Pandiyarajan, S., Velayutham, G., Liao, AH. et al. A biogenesis construction of CuO@MWCNT via Chenopodium album extract: an effective electrocatalyst for synaptic plasticity neurodegenerative drug pollutant detection. Environ Sci Pollut Res 30, 79744–79757 (2023). https://doi.org/10.1007/s11356-023-25629-x
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DOI: https://doi.org/10.1007/s11356-023-25629-x