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Noise exposure and risk of myocardial infarction incidence and mortality: a dose–response meta-analysis

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Abstract

The strength and shape of the dose–response relationship between different types of noise and myocardial infarction (MI) remain unclear. Therefore, we aimed to summarize the evidence of the association between various types of noise and MI incidence and mortality through a dose–response meta-analysis. We performed a systematic search of the PubMed, Embase, and Web of Science databases up to December 19, 2021. The generalized least-squares method and restricted cubic splines were used to assess the potential linear and nonlinear dose–response relationships between noise exposure and the risk of MI events. Twenty observational studies with 34 reports met the eligibility criteria. In the linear models, the pooled relative risk and corresponding 95% confidence interval (CI) for MI incidence was 1.04 (95% CI: 1.02 − 1.05), and the MI mortality was 1.02 (95% CI: 1.02 − 1.03) for each 10 dB(A) increase in noise exposure. In addition, we observed an approximately J-shaped dose–response relationship between noise and MI mortality (Pnonlinearity = 0.0037), whereas the threshold for the statistical impact of noise on MI mortality may be 42 dB(A). Our findings support the notion that various types of noise exposure have a positive dose–response relationship with the risk of MI incidence and mortality.

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Data availability

Some of the data and materials used in this study can be found in the Appendix Material. More details can be obtained from the corresponding author (Wenning Fu).

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Funding

This work was supported by the Program of Excellent Doctoral (Postdoctoral) of Zhongnan Hospital of Wuhan University (Grant.ZNYB2021003), Key Laboratory of Emergency and Trauma (Hainan Medical University), and Hainan Provincial Science and Technology Major Project (Grant.ZDKJ202004).

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Authors and Affiliations

  1. School of Nursing, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China

    Yifang Liu, Jing Wen & Wenning Fu

  2. School of Public Health, Hainan Medical University, Haikou, 571199, China

    Shijiao Yan

  3. Department of Neurology, Zhongnan Hospital of Wuhan University, 430071, Wuhan, China

    Li Zou

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  1. Yifang Liu
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  3. Li Zou
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Contributions

Yifang Liu: conceptualization, data curation, and writing—original draft preparation.

Shijiao Yan: methodology, formal analysis, visualization.

Li Zou: methodology, data curation, and writing—reviewing and editing.

Jing Wen: formal analysis and visualization.

Wenning Fu: conceptualization, supervision, and writing—reviewing and editing.

All authors read and approved the final manuscript.

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Correspondence to Wenning Fu.

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ESM 1

Sensitivity analysis plots for noise and myocardial infarction incidence (A: categorical analysis; B: dose response analysis)(PNG 220 kb)

High Resolution (TIF 4894 kb)

ESM 2

Sensitivity analysis plots for noise and myocardial infarction mortality (A: categorical analysis; B: dose response analysis)(PNG 133 kb)

High Resolution (TIF 4894 kb)

ESM 3

Funnel plots for myocardial infarction incidence (A and B: categorical analysis; C and D: dose response analysis)(PNG 53 kb)

High Resolution (TIF 5826 kb)

ESM 3

Funnel plots and filled funnels for myocardial infarction mortality (A and B: categorical analysis; C and D: dose response analysis)(PNG 131 kb)

High Resolution (TIF 11632 kb)

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Liu, Y., Yan, S., Zou, L. et al. Noise exposure and risk of myocardial infarction incidence and mortality: a dose–response meta-analysis. Environ Sci Pollut Res 29, 46458–46470 (2022). https://doi.org/10.1007/s11356-022-20377-w

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