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Evaluation of hemp (Cannabis sativa L.) as an industrial crop: a review

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Abstract

Rising human population has increased the utilization of available resources for food, clothes, medicine, and living space, thus menacing natural environment and mounting the gap between available resources, and the skills to meet human desires is necessary. Humans are satisfying their desires by depleting available natural resources. Therefore, multifunctional plants can contribute towards the livelihoods of people, to execute their life requirements without degrading natural resources. Thus, research on multipurpose industrial crops should be of high interest among scientists. Hemp, or industrial hemp, is gaining research interest because of its fastest growth and utilization in commercial products including textile, paper, medicine, food, animal feed, paint, biofuel, biodegradable plastic, and construction material. High biomass production and ability to grow under versatile conditions make hemp, a good candidate species for remediation of polluted soils also. Present review highlights the morphology, adaptability, nutritional constituents, textile use, and medicinal significance of industrial hemp. Moreover, its usage in environmental conservation, building material, and biofuel production has also been discussed.

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References

  • Aluko R (2017) Hemp Seed (Cannabis sativa L.) Proteins. https://doi.org/10.1016/B978-0-12-802778-3.00007-X

  • Amaducci D, Scordia FH, Liu Q, Zhang H, Guo G, Testa SL et al (2015) Key cultivation techniques for hemp in Europe and China. Ind Crops Prod 68:2–16

    Article  CAS  Google Scholar 

  • Amaducci S, Colauzzi M, Zatta A, Venturi G (2008b) Flowering dynamics in monoecious and dioecious hemp genotypes. J Ind Hemp 13:5–19

    Article  Google Scholar 

  • Amaducci S, Pelatti F, Bonatti PM (2005) Fibre development in hemp as affected by agrotechnique: preliminary results of a microscopic study. J Ind Hemp 10:31–48

    Article  Google Scholar 

  • Amaducci S, Zatta A, Raffanini M, Venturi G (2008a) Characterisation of hemp (Cannabis sativa L.) roots under different growing conditions. Plant Soil 313:227–235

    Article  CAS  Google Scholar 

  • Amon T, Amon B, Kryvoruchko V, Zollitsch W, Mayer K, Gruber L (2007) Biogas production from maize and dairy cattle manure-Influence of biomass composition on the methane yield. Agric Ecosyst Environ 118:173–182

    Article  CAS  Google Scholar 

  • Andre CM, Hausman JF, Guerriero G (2016) Cannabis sativa: the plant of the thousand and one molecules. Front Plant Sci 7:19

    Article  Google Scholar 

  • Angelova V, Ivanova R, Delibaltova V, Ivanov K (2004) Bio-accumulation and distribution of heavy metals in fibre crops (flax, cotton and hemp). Indust Crops Prod 19:197–205

    Article  CAS  Google Scholar 

  • Balodis O, Bartuševics J, Gaile Z (2011) Biomass yield of different plants for biogass production. Environ Technol Resour Proceed Intl Sci Pract Conf 1:238

  • Baraniecki P, Grabowska L, Mankowski J (1995) Flax and hemp in areas made derelict by the copper industry. Nat Fibres XXXIX:79–85

    Google Scholar 

  • Baraniecki P, Mankowski J (1995) Hemp fibre as a raw material for paper production in the aspect of natural environment protection. ZemedelskaTechnika 3:85–88

    Google Scholar 

  • Benfratello S, Capitano C, Peri G, Rizzo G, Scaccianoce G, Sorrentino G (2013) Thermal and structural properties of a hemp-lime biocomposite. Construc Build Mat 48:745–754

    Article  Google Scholar 

  • Bhutto AW, Bazmi AA, Zahedi G (2011) Greener energy: Issues and challenges for Pakistan-Biomass energy prospective. Renew Sustain Energy Rev 15:3207–3219

    Article  Google Scholar 

  • Bosca I, Karus M (1997) The Cultivation of Hemp: Botany, Varieties, Cultivation and Harvesting. Hemptech, Sebastopol, California. ISBN 1-886874-04-4.

  • Burczyk H, Grabowska L, Kołodziej J, Strybe M (2008) Industrial hemp as a raw material for energy production. J Ind Hemp 13:37–48

    Article  CAS  Google Scholar 

  • Cai P, Fu X, Deng AG, Zhan XJ, Cai GM, Li SX (2010) Anti-aging effect of hemp seed oil, protein and lignanamide of bama on old mice. Cent South Pharm 8:165–170

    Google Scholar 

  • Callaway JC (2004) Hempseed as a nutritional resource: an overview. Euphytica 140:65–72

    Article  Google Scholar 

  • Casas XA, Rieradevalli Pons J (2005) Environmental analysis of the energy use of hemp analysis of the comparative life cycle: diesel oil vs. hemp diesel. Int J Agric Resour Govern Ecol 4:133–139

  • Castleman T (2006) Hemp biomass for energy. Fuel and Fiber Company, Sacramento, USA

  • Chagas MH, Zuardi AW, Tumas V, Pena-Pereira MA, Sobreira ET, Bergamaschi MM et al (2014) Effects of cannabidiol in the treatment of patients with Parkinson's disease: an exploratory double-blind trial. J Psychopharmacol 28:1088–1098

    Article  CAS  Google Scholar 

  • Nissen L, Zatta A, Stefanini I, Grandi S, Sgorbati B, Biavati B, Monti A (2010) Characterization and antimicrobial activity of essential oils of industrial hemp varieties (Cannabis sativa L.). Fitoterapia 81:413–419

    Article  CAS  Google Scholar 

  • Chase M (1998) The angiosperm phylogeny group: an ordinal classification for the families of flowering plants. Ann Missouri Botanical Garden 85:531–553

    Article  Google Scholar 

  • Chen T, He J, Zhang J, Li X, Zhang H, Hao J, Li L (2012) The isolation and identification of two compounds with predominant radical scavenging activity in hempseed (seed of Cannabis sativa L.). Food Chem 134:1030–1037

    Article  CAS  Google Scholar 

  • Cheng CW, Bian ZX, Zhu LX, Wu JC, Sung JJ (2011) Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. Am J Gastroenterol 106:120–129

    Article  Google Scholar 

  • Citterio S, Santagostino A, Fumagalli P, Prato N, Ranalli P, Sgorbati S (2003) Heavy metal tolerance and accumulation of Cd, Cr and Ni by Cannabis sativa L. Plant and Soil 256:243–252

    Article  CAS  Google Scholar 

  • Da Porto C, Decorti D, Natolino A (2014) Separation of aroma compounds from industrial hemp inflorescences (Cannabis Sativa L.) by supercritical CO2 extraction and on-line fractionation. Ind Crops Prod 58:99–103

    Article  CAS  Google Scholar 

  • Da Porto C, Decorti D, Natolino A (2015) Potential oil yield, fatty acid composition, and oxidation stability of the hempseed oil from four Cannabis sativa L. cultivars. J Diet Suppl 12:1–10

    Article  CAS  Google Scholar 

  • Darkovska-Serafimovska M, Serafimovska T, Arsova-Sarafinovska Z, Stefanoski S, Keskovski Z, Balkanov T (2018) Pharmacotherapeutic considerations for use of cannabinoids to relieve pain in patients with malignant diseases. J Pain Res 11:837–842

    Article  Google Scholar 

  • Das L, Liu E, Saeed A, Williams DW, Hu H, Li C, Ray AE, Shi J (2017) Industrial hemp as a potential bioenergy crop in comparison with kenaf, switchgrass and biomass sorghum. Bioresourc Technol 244:641–649

    Article  CAS  Google Scholar 

  • Deferne JL, Pate DW (1996) Hemp seed oil: a source of valuable essential fatty acids. J Int Hemp Assn 3:4–7

    Google Scholar 

  • Devi V, Khanam S (2019) Comparative study of different extraction processes for hemp (Cannabis sativa) seed oil considering physical, chemical and industrial-scale economic aspects. Journal of Cleaner Production 207:645–657

    Article  CAS  Google Scholar 

  • Dhakal HN, Zhang Z (2015) Biofiber reinforcements in composite materials. pp 86-103. https://doi.org/10.1533/9781782421276.1.86

  • Dutt D, Sing V, Ray AK, Mukherjee S (2003) Development of specialty papers in an Art: Electrical insulation paper from indigenous raw materials - Part IX. J Scient Industrial Res 62:1145–1151

    CAS  Google Scholar 

  • Dutt D, Tyagi CH, Malik RS (2007) Studies on effect of growth factor on morphological, chemical and pulp and papermaking characteristics and its impact on fluff generation. Ind J Chem Technol 14:626–634

    CAS  Google Scholar 

  • Dutt D, Upadhyaya JS, Ray AK, Upadhyaya MK (2002) Development of specialty papers is an art: Wax match tissue paper from indigenous raw materials - Part I. J Sci Indust Res 61:1046–1050

    CAS  Google Scholar 

  • Eriksson M, Wall H (2012) Hemp seed cake in organic broiler diets. Anim Feed Sci Technol 171:205–213

  • Ferrante C, Recinella L, Ronci M, Menghini L, Brunetti L, Chiavaroli A, Leone S, Iorio LD, Carradori S, Tirillini B, Angelini P, Covino S, Venanzoni R, Orlando G (2019) Multiple pharmacognostic characterization on hemp commercial cultivars: Focus on inflorescence water extract activity. Food Chem Toxicol 125:452–461

    Article  Google Scholar 

  • Finnan J, Styles D (2013) Hemp: A more sustainable annual energy crop for climate and energy policy. Energy Policy 58:152–162

    Article  Google Scholar 

  • Fiorini D, Molle A, Nabissi M, Santini G, Benelli G, Maggi F (2019) Valorizing industrial hemp (Cannabis sativa L.) by-products: Cannabidiol enrichment in the inflorescence essential oil optimizing sample pre-treatment prior to distillation. Industrial Crops Prod 128:581–589

    Article  CAS  Google Scholar 

  • Frassinetti S, Moccia E, Caltavuturo L, Gabriele M, Longo V, Bellani L, Giorgi G, Giorgetti L (2018) Nutraceutical potential of hemp (Cannabis sativa L.) seeds and sprouts. Food Chem 262:56–66

    Article  CAS  Google Scholar 

  • Gakhar N, Goldberg E, Jing M, Gibson R, House JD (2012) Effect of feeding hemp seed and hemp seed oil on laying hen performance and egg yolk fatty acid content: Evidence of their safety and efficacy for laying hen diets. Poult Sci 91:701–711

    Article  CAS  Google Scholar 

  • Galasso I, Russo R, Mapelli S, Ponzoni E, Brambilla IM, Battelli G, Reggiani R (2016) Variability in Seed Traits in a Collection of Cannabis sativa L. Genotypes. Front Plant Sci 7:688

    Google Scholar 

  • García-Tejero IF, Durán-Zuazo VH, Pérez-Álvarez R, Hernández A, Casano S, Morón M, Muriel-Fernández1 JL (2014) Impact of plant density and irrigation on yield of hemp (Cannabis sativa L.) in a Mediterranean Semi-arid Environment. J Agr Sci Tech 16:887-895.

  • Gibb DJ, Shah MA, Mir PS, Mcallister TA (2005) Effect of full-fat hemp seed on performance and tissue fatty acids of feedlot cattle. Canadian J Animal Sci 85:223–230

    Article  CAS  Google Scholar 

  • Göhl B (1982) Les aliments du bétail sous les tropiques. FAO, Division de Production et Santé Animale, Roma, Italy.

  • Gowran A, Noonan J, Campbell VA (2011) The multiplicity of action of cannabinoids: implications for treating neurodegeneration. CNS NeurosciTher 17:637–644

    Article  CAS  Google Scholar 

  • Grotenhermen F, Russo E, Zuardi AW (2016) Even high doses of oral cannabidol do not cause THC-like effects in humans: Comment on Merrick et al. Cannabis and Cannabinoid Res 1:102–112. https://doi.org/10.1089/can.2015.0004 Cannabis Cannabinoid Res. 2017, 2:1-4

    Article  CAS  Google Scholar 

  • Grubeša IN, Markovic’ B, Gojevic’ A, Brdaric J (2018) Effect of hemp fibers on fire resistance of concrete. Construction and Building Materials 184:473–484

    Article  CAS  Google Scholar 

  • Halle I, Schöne F (2013) Influence of rapeseed cake linseed cake and hemp seed cake on laying performance of hens and fatty acid composition of egg yolk. J Verbrauch Lebensm 8(3):185–193. https://doi.org/10.1007/s00003-013-0822-3

  • Harris AT, Riddlestone S, Bell Z, Hartwell PR (2008) Towards zero emission pulp and paper production: the BioRegionalMiniMill. J Clean Prod 16:1971–1979

    Article  CAS  Google Scholar 

  • Hartsel JA, Eades J, Hickory B, Makriyannis A (2016) Cannabis sativa and hemp. https://doi.org/10.1016/B978-0-12-802147-7.00053-X

  • Hessle A, Eriksson M, Nadeau E, Turner T, Johansson B (2008) Cold-pressed hempseed cake as a protein feed for growing cattle. ActaAgriculturaeScandinavica, Sec A - An Sci. 58:136-145.

  • Hill KP (2015) Medical marijuana for treatment of chronic pain and other medical and psychiatric problems: a clinical review. JAMA 313:2474–2483

    Article  CAS  Google Scholar 

  • Höppner F, Menge-Hartmann U (2007) Yield and quality of fibre and oil of fourteen hemp cultivars in Northern Germany at two harvest dates. Landbauforsch Volk 57:219–232

    Google Scholar 

  • Ingrao C, Giudice AL, Bacenetti J, Tricase C, Dotelli G, Fiala M, Siracusa V, Mbohwa C (2015) Energy and environmental assessment of industrial hemp for building applications: A review. Renewable and Sustainable Energy Reviews 51:29–42

    Article  CAS  Google Scholar 

  • Jadoon KA, Tan GD, O’Sullivanl SE (2017) A single dose of cannabidiol reduces blood pressure in healthy volunteers in a randomized crossover study. JCI Insight 15:e93760

    Article  Google Scholar 

  • Jami T, Karade SR, Singh LP (2019) A review of the properties of hemp concrete for green building applications. J Cleaner Prod 239:117852

    Article  Google Scholar 

  • Jarabo R, Fuente E, Monte MC, Savastano H, Jr Mutje P, Negro C (2012) Use of cellulose fibers from hemp core in fiber-cement production. Effect on flocculation, retention, drainage and product properties. Industr Crops Prod 39:89–96

    Article  CAS  Google Scholar 

  • Jeyasingam JT (1994) Industrial experience in the manufacture of cigarette tissue using hemp. TAPPI Nonwood Plant Fiber Progress Report No 21:163–178

    Google Scholar 

  • Johnson R (2014) Hemp as an agricultural commodity. Congressional Res Serv:1–29

  • Johnson R (2017) Hemp as an agricultural commodity, (Ed.) C.R. Service.

  • Kahn CM (2005) The Merck Veterinary Manual. Merck, 9th edition.

  • Kalmendal R (2008) Hemp seed cake fed to broilers. Swedish University of Agricultural Sciences. Department of Animal Nutrition and Management.

  • Khan RU, Durrani FR, Chand N, Anwar H (2010) Influence of feed supplementation with Cannabis sativa on quality of broilers carcass. Pakistan Vet J 30:34–38

    CAS  Google Scholar 

  • Khan RU, Durrani FR, Chand N, Anwar H, Naz S, Farooqi FA, Manzoor MN (2009) Effect of Cannabis sativa fortified feed on muscle growth and visceral organs in broiler chicks. Int J Biol Biotech 6:179–182

    Google Scholar 

  • Kiralan M, Gül V, Kara SM (2010) Fatty acid composition of hempseed oils from different locations in Turkey. Spanish Journal of Agricultural Research 8:385–390

    Article  Google Scholar 

  • Kladar N, Čonić BS, Božin B, Torović L (2021) European hemp-based food products – Health concerning cannabinoids exposure assessment. Food Control 129:108233

    Article  CAS  Google Scholar 

  • Kolodziejczyk P, Ozimek L, Kozlowska J (2012) The application of flax and hemp seeds in food, animal feed and cosmetics production. In: Kozlowski RM (ed) Handbook of natural fibres, vol 2. Elsevier, Amsterdam, pp 329–366

  • Kolosov C (2009) Evaluating the public interest: Regulation of industrial hemp under the controlled substances act. UCLA Law Review:57

  • Korus J, Witczak M, Ziobro R, Juszczak L (2017) Hemp ( Cannabis sativa subsp. sativa ) flour and protein preparation as natural nutrients and structure forming agents in starch based gluten-free bread. LWT- Food Sci Techn. https://doi.org/10.1016/j.lwt.2017.05.046

  • Kozlowski RL, Grabowska L, Baranieski P, Mscicz J (1994) Recultivation by flax and hemp culture of soil polluted by heavy metals. Natural Fibres (special ed.), 159-164.

  • Latif E, Lawrence M, Shea A, Walker P (2015) Moisture buffer potential of experimental wall assemblies incorporating formulated hemp-lime. Build Environ 93:199–209

    Article  Google Scholar 

  • Leizer C, Ribnicky DM, Poulev A, Dushenkov V, Raskin I (2000) The composition of hemp seed oil and its potential as an important source of nutrition. J Nutraceuticals Funct Med Foods 2:35–53

    Article  Google Scholar 

  • Li HL (1973) An archaeological and historical account of Cannabis in China. Economic Botany 28:437–448

    Article  Google Scholar 

  • Li HL (1974) The origin and use of Cannabis in Eastern Asia linguistic-cultural implications. Economic Botany 28:293–301

    Article  Google Scholar 

  • Li M, RongFu G (2007) Immune effects of hemp seed meal in Tegel broilers. J Yunnan Agric Univ 22(1):82–85

  • Li SY, Stuart JD, Li Y, Parnas RS (2010) The feasibility of converting Cannabis sativa L. oil into biodiesel. Bioresourc Technol 101:8457–8460

    Article  CAS  Google Scholar 

  • Lin ZM, Chen LM, Liang ZM, Xia X (2016) The effect of different extractants from Hemp seed in mice with experimental Alzheimer's disease. Pharmacol Clin Chin Materia Medica 32:130–134

    CAS  Google Scholar 

  • Luo J, Yin J-H, Wu H-Z, Wei Q (2003) Extract from Fructus cannabis activating calcineurin improved learning and memory in mice with chemical drug-induced dysmnesia. Acta Pharmacol Sin 24:1137–1142

    CAS  Google Scholar 

  • Maalouf C, Le ADT, Vasseur-Umurigirwa BS, Lachi M, Douzane O (2014) Study of hygrothermal behaviour of a hemp concrete building envelope under summer conditions in France. Energy Build 77:48–57. https://doi.org/10.1016/j.enbuild.2014.03.040

    Article  Google Scholar 

  • Mahmoudi M, Farhoomand P, Nourmohammadi R (2012) Effects of different levels of hemp seed (Cannabis Sativa L.) and dextran oligosaccharide on growth performance and antibody titer response of broiler chickens. Ital J Anim Sci 14:3473

  • Maiolo SA, Fan P, Bobrovskaya L (2018) Bioactive constituents from cinnamon, hemp seed and polygonumcuspidatum protect against H2O2 but not rotenone toxicity in a cellular model of Parkinson's disease. J Trad Complem Med 8:420–427

    Article  Google Scholar 

  • Mazhoud B, Collet F, Pretot S, Chamoin J (2016) Hygric and thermal properties of hemp lime plasters. Build Environ 96:206–216

    Article  Google Scholar 

  • McAllister SD, Christian RT, Horowitz MP, Garcia A, Desprez PY (2007) Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells. Mol Cancer Ther 6:2921–2927

    Article  CAS  Google Scholar 

  • Meijer WJM, van der Werf HMG, Mathijssen EWJM, van den Brink PWM (1995) Constraints to dry matter production in fibre hemp (Cannabis sativa L.). Eur J Agron 4:109–117

    Article  Google Scholar 

  • Mikulec A, Kowalski S, Sabat R, Skoczylas L, Tabaszewska M, Wywrocka-Gurgul A (2019) Hemp flour as a valuable component for enriching physicochemical and antioxidant properties of wheat bread. LWT-Food Sci Techn 102:164–172

    Article  CAS  Google Scholar 

  • Moldzio R, Pacher T, Krewenka C, Kranner B, Novak J, Duvigneau JC, Rausch WD (2012) Effects of cannabinoids Δ(9)-tetrahydrocannabinol, Δ(9)-tetrahydrocannabinolic acid and cannabidiol in MPP+ affected murine mesencephalic cultures. Phytomedicine 19:819–824

    Article  CAS  Google Scholar 

  • Mölleken H, Theimer RR (1997) Survey of minor fatty acids in Cannabis sativa L. fruits of various origins. J Int Hemp Assoc 4:500–504

    Google Scholar 

  • Montserrat-de la Paz S, Marin-Aguilar F, García-Giménez MD, Fernández-Arche MA (2014) Hemp (Cannabis sativa L.) seed oil: Analytical and phytochemical characterization of the unsaponifiable fraction. J Agricult Food Chem 62:1105–1110

    Article  CAS  Google Scholar 

  • Mustafa AF, McKinnon JJ, Christensen DA (1999) The nutritive value of hemp meal for ruminants. Can J Anim Sci 79:91–95

    Article  Google Scholar 

  • Mutjé P, Lòpez A, Vallejos ME, Lopez JP (2007) Full exploitation of Cannabis sativa as reinforcement/filler of thermoplastic composite materials. Composites Part A Appl Sci Manuf 38:369–377

    Article  CAS  Google Scholar 

  • National Academies of Sciences, Engineering, and Medicine (2017) The health effects of cannabis and cannabinoids: Current state of evidence and recommendations for research. The National Academies Press, Washington, DC

  • Oláh A, Tóth BI, Borbíró I, Sugawara K, Szöllõsi AG, Czifra G, Pál B, Ambrus L, Kloepper J, Camera E, Ludovici M, Picardo M, Voets T, Zouboulis CC, Paus R, Bíró T (2014) Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes. J Clin Invest 124:3713–3724

    Article  CAS  Google Scholar 

  • Pain S (2015) A potted history. Nature 525:S10–S11. https://doi.org/10.1038/525S10a

    Article  CAS  Google Scholar 

  • Pervaiz M, Sain M (2003) Carbon storage potential in natural fiber composites. Resour Conserv Recycl 39:325–340

    Article  Google Scholar 

  • Piotrowski S, Carus M (2011) Ecological benefits of hemp and flax cultivation and products. Report Nova Institut fur Okologie und Innov

  • Rajesh M, Mukhopadhyay P, Batkai S, Patel V, Saito K, Matsumoto S et al (2010) Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy. J Am Coll Cardiol 56:2115–2125

    Article  CAS  Google Scholar 

  • Rehman MSU, Rashid N, Saif A, Mahmood T, Han JI (2013) Potential of bioenergy from industrial hemp (Cannabis Sativa): Pakistan perspective. Renewable Sustainable Energy Rev 18:154–164

    Article  Google Scholar 

  • Rezapour-Firouzi S, Arefhosseini SR, Mehdi F, Mehrangiz E-M, Baradaran B, Sadeghihokmabad E, Mostafaei S, Fazljou SMB, Torbati MA, Sanaie S, Zamani F (2013) Immunomodulatory and therapeutic effects of Hot-nature diet and co-supplemented hemp seed, evening primrose oils intervention in multiple sclerosis patients. Complement Ther Med 21:473–480

    Article  Google Scholar 

  • Rice B (2008) Hemp as a Feedstock for Biomass-to-Energy Conversion. J Industrial Hemp 13:145–156

    Article  CAS  Google Scholar 

  • Robbins L, Snell W, Halion G, Maynard L, Dillon C, Spalding D (2013) ‘Economic considerations for growing industrial hemp: Implications for Kentucky’s farmers and agricultural economics’. University of Kentucky.

  • Rodriguez-Leyva D, Pierce GN (2010) The cardiac and haemostatic effects of dietary hempseed. Nutrit Metab 7:32

    Article  CAS  Google Scholar 

  • Saberivand A, Karimi I, Becker LA, Moghaddam A, Azizi-Mahmoodjigh S, Yousefi M, Zavareh S (2010) The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol 32:467–473

    Article  CAS  Google Scholar 

  • Sales A, Crestani C, Guimarães F, Sâmia J (2018) Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels. Progress in Neuro-Psychopharmacology and Biological Psychiatry 86. https://doi.org/10.1016/j.pnpbp.2018.06.002.

  • Sankari HS (2000) Comparison of bastfibre yield and mechanical fibre properties of hemp (Cannabis sativa L.) cultivars. Industrial Crops Products 11:73–84

    Article  Google Scholar 

  • Schäfer T, Honermeier B (2006) Effect of sowing date and plant density on the cell morphology of hemp (Cannabis sativa L.). Ind Crops Prod 23:88–98

    Article  Google Scholar 

  • Schluttenhofer C, Yuan L (2017) Challenges towards revitalizing hemp: a multifaceted crop. Trends in Plant Sci 22:11–929. https://doi.org/10.1016/j.tplants.2017.08.004

    Article  CAS  Google Scholar 

  • Sgriccia N, Hawley MC, Misra M (2008) Characterization of natural fiber surfaces and natural fiber composites. Compos Part A Appl Sci Manuf 39:1632–1637

    Article  CAS  Google Scholar 

  • Shahid S, Chand N, Khan R, Suhail S, Khan NA (2015) Alternations in Cholesterol and Fatty Acids Composition in Egg Yolk of Rhode Island Red x Fyoumi Hens Fed with Hemp Seeds (Cannabis sativa L.). J Chem 4:1–6

    Article  Google Scholar 

  • Shahzad A (2012) Hemp fiber and its composites-a review. J Compos Mater 46:973–986

    Article  CAS  Google Scholar 

  • Shannon S, Abihm MD (2016) Effectiveness of Cannabidiol Oil for Pediatric Anxiety and Insomnia as Part of Posttraumatic Stress Disorder: A Case Report. Perm J 20:16–005

    Article  Google Scholar 

  • Shrivastava A, Kuzontkoski PM, Groopman JE, Prasad A (2011) Cannabidiol induces programmed cell death in breast cancer cells by coordinating the cross-talk between apoptosis and autophagy. Mol Cancer Ther 10:1161–1172

    Article  CAS  Google Scholar 

  • Siudem P, Wawer I, Paradowska K (2019) Rapid evaluation of edible hemp oil quality using NMR and FT-IR spectroscopy. J Mole Struct 1177:204–208

    Article  CAS  Google Scholar 

  • Šťastník O, Filip K, Hana S, Trojan V, Vyhnánek T, Pavlata L, Eva M (2015) The effect of hempseed cakes on broiler chickens performance parameters.

  • Švec I, Hrušková M (2013) Crumb evaluation of bread with hemp products addition by means of image analysis. Acta Univ Agric Silvic Mendel Brun 61:1867–1872

    Article  Google Scholar 

  • Švec I, Hrušková M (2015) Properties and nutritional value of wheat bread enriched by hemp products. Potravinarstvo 9. https://doi.org/10.5219/487

  • Tan J, Bhate K (2015) A global perspective on the epidemiology of acne. Br J Dermatol 172:3–12

    Article  Google Scholar 

  • Tofana L, Teodosiua C, Padurarua C, Wenkert R (2013) Cobalt (II) removal from aqueous solutions by natural hemp fibers: Batch and fixed-bed column studies. Appl Surface Sci 285:33–39

    Article  CAS  Google Scholar 

  • van der Werf HMG, Turunen L (2008) The environmental impacts of the production of hemp and flax textile yarn. Ind Crop Prod 27:1–10

    Article  Google Scholar 

  • van der Werf HMG (2004) Life cycle analysis of field production of fibre hemp, the effect of production practices on environmental impacts. Euphytica 140:13–23

    Article  Google Scholar 

  • Vonapartis E, Aubin MP, Seguin P, Mustafa AF, Charron JB (2015) Seed composition of ten industrial hemp cultivars approved for production in canada. J Food Compost Anal 39:8–12

    Article  CAS  Google Scholar 

  • Watt G, Karl T (2017) In vivo evidence for therapeutic properties of cannabidiol (CBD) for Alzheimer's disease. Front Pharmacol 8:20

    Article  CAS  Google Scholar 

  • Yanchev I, Jalnov I, Terziev I (2000) Hemps (Canabis sativa L.) capacities for restricting the heavy metal soil pollution. Plant Sci 37:532–537

    CAS  Google Scholar 

  • Yu LL, Zhou KK, Parry J (2005) Antioxidant properties of cold-pressed black caraway, carrot, cranberry, and hemp seed oils. Food Chem 91:723–729

    Article  CAS  Google Scholar 

  • Zanelati TV, Biojone C, Moreira FA, Guimarães FS, Joca SR (2010) Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. Br J Pharmacol 159:122–128

    Article  CAS  Google Scholar 

  • Zuardi AW (2006) History of cannabis as a medicine: a review. Braz J Psychiatry 28:153–157. https://doi.org/10.1590/S1516-44462006000200015

    Article  Google Scholar 

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Acknowledgements

All authors are thankful to the National Natural Science Foundation of China (31760403 and31871671) and China Agriculture Research System (CARS-16-E15) for supporting this work.

Funding

This research was supported by a grant from the National Natural Science Foundation of China (31760403 and31871671) and China Agriculture Research System (CARS-16-E15).

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Authors and Affiliations

  1. School of Agriculture, Yunnan University, Kunming, 650504, Yunnan, China

    Muzammal Rehman, Guanghui Du, Yang Yang, Kailei Tang, Fei-Hu Liu & Gang Deng

  2. Hainan Key Laboratory for Sustainable Utilization of Tropical Bioresource, College of Tropical Crops, Hainan University, Haikou, 570228, China

    Shah Fahad

  3. Department of Agronomy, the University of Haripur, Khyber Pakhtunkhwa, 22620, Pakistan

    Shah Fahad

  4. College of Agriculture and Life Sciences, Kunming University, Kunming, 650241, Yunnan, China

    Xia Cheng

  5. College of Plant Science and Technology, Huazhong Agricultural University, Wuhan, 430070, Hubei, China

    Lijun Liu

Authors
  1. Muzammal Rehman
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  2. Shah Fahad
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  3. Guanghui Du
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  4. Xia Cheng
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  5. Yang Yang
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  6. Kailei Tang
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  7. Lijun Liu
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  8. Fei-Hu Liu
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  9. Gang Deng
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Contributions

“Muzammal Rehman” prepared the manuscript. “Shah Fahad,” “Guanghui Du,” “Xia Cheng,” “Yang Yang,” and “Kailei Tang” helped in preparation of manuscript. “Feihu Liu,” “Lijun Liu,” and “Gang Deng” reviewed and improved the manuscript.

Corresponding authors

Correspondence to Shah Fahad, Fei-Hu Liu or Gang Deng.

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Rehman, M., Fahad, S., Du, G. et al. Evaluation of hemp (Cannabis sativa L.) as an industrial crop: a review. Environ Sci Pollut Res 28, 52832–52843 (2021). https://doi.org/10.1007/s11356-021-16264-5

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