Abstract
The relationship between occupational exposure and different skin diseases including scalp psoriasis and Pityriasis amiantacea has been studied. The information about imbalance of essential trace elements in psoriatic patients is still scarce. In the present follow-up study, the scalp hair and blood samples of patients (labors of cement factory) have different skin disorders (plaque’s psoriasis and Pityriasis amiantacea) and were analyzed for zinc (Zn) and selenium (Se) before and after treatment with mineral supplements. For comparative purposes, both biological samples of referents who do not have any skin disease (office workers and labors of cement industry) were also analyzed for Zn and Se using an atomic absorption spectrometer. The result indicates a significant decrease in the concentrations of Se and Zn in both biological samples of patients with scalp psoriasis and P. amiantacea as compared with referents/controls, whereas the referent labor has not any skin disease with 15–25% lower values of both essential trace elements as compared to office worker, possibly due to poor diet.
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Dr Atif (dermatologist FCPS) made the project and took part in designing the study, clinical diagnosis, selecting patients, and sample collection and made file of each selected subject. Dr Hassan Imran Afridi and Dr Muhammad Balal Arain took part in writing the manuscript, designing the study, and analysis of the biological and mineral supplements. Professor Tasneem G Kazi participated in writing the manuscript and gathering and generating the data as well as proofreading and correction of language.
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The research project is approved by the ethical committee of Sindh University and Liaquat Medical University of Health and Sciences.
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Written informed consent was obtained from all study participants prior to the collection of scalp hair and blood samples.
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Responsible Editor: Lotfi Aleya
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Highlights
• Occupational exposure can cause skin diseases, scalp psoriasis, and Pityriasis amiantacea.
• The intake of essential mineral supplement can improve damage of the scalp’s skin for curing.
• The levels of Se and Zn in blood samples of patients with skin disorder were significantly lower than those of controls.
• The mineral supplement and medicated shampoo might be improving the skin disorders.
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Kazi, A.G., Afridi, H.I., Arain, M.B. et al. Adverse impact of occupational exposure on Laborers of cement industry have scalp psoriasis and Pityriasis amiantacea with deficiency of zinc and selenium: impact of mineral supplement. Environ Sci Pollut Res 28, 68330–68337 (2021). https://doi.org/10.1007/s11356-021-15307-1
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DOI: https://doi.org/10.1007/s11356-021-15307-1