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Organopesticides and fertility: where does the link lead to?

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Abstract

Organopesticides (OPs) are a group of various synthetic chemicals prevalently used in agriculture and homestead plantations. OPs were originally developed to remove insects, weeds, and other pests from agricultural fields for improving crop yields. Modern pesticides including organochlorine pesticides, organophosphorus pesticides, and amido-formyl ester are closely related to our lives. Many people are exposed to various OPs during farming practice. OPs can cause adverse effects and provoke serious impacts on normal reproductive functions of humans, resulting in loss of fertility. The effects of OPs in the reproductive system include association with fluctuation in the levels of sex hormones, delayed menstrual cycle, ovarian dysfunction, alteration in ovary weight, changes of follicle growth, altered oocyte feasibility, and changed the quality of spermatogenesis. Current literature clearly states that exposure to various OPs can impair the fertility of women and cause a high risk of reproductive potential. However, investigations on OPs exposure to woman fertility remain scarce. This review highlights effects of exposure to OPs on the fertility of occupational women and mechanisms of action involved in such effects on the reproductive function of women along with their related impacts.

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Funding

This paper was supported by the KU Research Professor Program of Konkuk University, Seoul, South Korea.

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Authors and Affiliations

  1. Department of Biotechnology, Sri Shakthi Institute of Engineering and Technology, Coimbatore, Tamil Nadu, 641062, India

    Baskar Venkidasamy & Ramkumar Samynathan

  2. Translational Research Platform for Veterinary Biologicals, Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Madhavaram Milk Colony, Chennai, Tamil Nadu, 600051, India

    Umadevi Subramanian

  3. College of Chemistry and Chemical Engineering, Hubei University, Wuhan, 430062, China

    Govindasamy Rajakumar

  4. Department of Technology of Food Products, K.G. Razumovsky Moscow State University of Technologies and Management (the First Cossack University), Moscow, Russia, 109004

    Mohammad Ali Shariati

  5. Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul, 05029, Republic of Korea

    Ill-Min Chung & Muthu Thiruvengadam

Authors
  1. Baskar Venkidasamy
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  2. Umadevi Subramanian
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  3. Ramkumar Samynathan
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  4. Govindasamy Rajakumar
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  5. Mohammad Ali Shariati
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  6. Ill-Min Chung
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  7. Muthu Thiruvengadam
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Contributions

B.V, U.S, G.R,. I.M.C, and M.T conceived the review idea and focus, drafted the article, and critically revised the article. R.S and M.A.S were involved in the reference collection, drawing figures, and writing the article. All authors have read and agreed to the published version of the manuscript.

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Correspondence to Muthu Thiruvengadam.

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Venkidasamy, B., Subramanian, U., Samynathan, R. et al. Organopesticides and fertility: where does the link lead to?. Environ Sci Pollut Res 28, 6289–6301 (2021). https://doi.org/10.1007/s11356-020-12155-3

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  • DOI: https://doi.org/10.1007/s11356-020-12155-3

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