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Lipid peroxidation of kidney of the turtle Mauremys reevesii caused by cadmium

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Abstract

This research was designed to investigate lipid peroxidation of the kidney of turtle (Mauremys reevesii) caused by cadmium. Turtles were injected intraperitoneally with cadmium at the concentration of 0 (control), 7.5, 15, and 30 mg/kg, and 5 turtles were taken from each group after exposure for 1 week (1 w), 2 weeks (2 w), and 3 weeks (3 w). Superoxide dismutase (SOD) and catalase (CAT) activities as well as glutathione (GSH) and malonyldialdehyde (MDA) contents in the homogenate of kidney tissue were analyzed. The results demonstrated that a short time of low dose of cadmium could stimulate the increase of SOD activity in the kidney of turtles, but a long time of high dose of cadmium could induce the decrease of SOD activity in the kidney of turtles. Cadmium could decrease CAT activity and GSH content in turtle kidney, but increased MDA content in turtle kidney. There were some other effects on the turtles, such as depression and diarrhea. The experimental results indicate that cadmium causes temporary oxidative stress on the kidney of turtles.

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Funding

This study was funded by Natural Science Foundation of Shanxi Province (grant number 201801D121229), Science and Technology Innovation Ability Cultivation Program of Shanxi University of Chinese Medicine (grant number 2018PY-008), Science and Technology Innovation Project of Colleges and Universities in Shanxi Province (grant number 2020L0458), Science and Technology Innovation Project of Colleges and Universities in Shanxi Province (grant number 2020L0460), and the Shanxi Key Laboratory of Chinese Medicine Encephalopathy (Shanxi University of Chinese Medicine) (grant number CME-OP-2017006).

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Author notes

  1. Aiguo Dong and Junfeng Huo contributed equally to this work.

Authors and Affiliations

  1. Shanxi Key Laboratory of Chinese Medicine Encephalopathy, Shanxi University of Chinese Medicine, Taiyuan, Shanxi Province, China

    Aiguo Dong, Junfeng Huo, Juanjuan Yan & Biwang Liu

  2. Bureau of agriculture and rural affairs of Qianan, Tangshan, Hebei Province, China

    Ailing Dong

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  1. Aiguo Dong
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  2. Junfeng Huo
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  3. Juanjuan Yan
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  4. Ailing Dong
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Contributions

Aiguo Dong and Junfeng Huo designed the study, performed the research, analyzed data, and wrote the paper. Juanjuan Yan was a major contributor in performing the research. Ailing Dong was a major contributor in writing the manuscript. Biwang Liu was a contributor in performing the research. All authors read and approved the final manuscript.

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Correspondence to Junfeng Huo.

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This study was approved by Shanxi University of Chinese Medicine (permit number: 2018LL054).

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Responsible editor: Philippe Garrigues

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Aiguo Dong and Junfeng Huo are Joint first co-authorship

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Dong, A., Huo, J., Yan, J. et al. Lipid peroxidation of kidney of the turtle Mauremys reevesii caused by cadmium. Environ Sci Pollut Res 28, 6811–6817 (2021). https://doi.org/10.1007/s11356-020-11054-x

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