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Biosurfactant electrospun nanofibers exhibit minimal side effects on the structure and function of the liver tissue in male rat model

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Abstract

Oil spills can result in significant damage to marine estuaries, rivers, lakes, wetlands, and shorelines. Electrospun nanofibers containing biosurfactant (ENFs) can be used to clean oil spills up and protect the environmental biology. Present work aimed to study the side-effects of prepared nanofibers on animal models. Screening of the prepared ECNFs on animals showed that three of them (PVA-5, PEO-1, and PEO-5) are safe to hepatic tissues and liver functions. Furthermore, oxidative stress did not change after using these nanofibers. The PVA-1 nanofibers, however, were found to cause major pathological changes in the liver tissue. In addition, PVA-1 nanofibers were proved to alter the total white blood count and the neutrophil percentages significantly in comparison to the control. In conclusion, PVA-5, PEO-1, and PEO-5 are safe to hepatic tissues and liver functions.

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Funding

This project was funded by the National Plan for Sciences, Technology and Innovation (MAARIFAH), King Abdualaziz City for Science and Technology, Kingdom of Saudi Arabia, Award Number (12-NAN2541-02).

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Authors and Affiliations

  1. Zoology Department, College of Science, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia

    Hossam Abd Rabou Ebaid, Ahmed Abdel-Mageed, Jameel Homoud Al-Tamimi, Iftekhar Hassan, Ahmed Mostafa Rady & Ibrahim Alhazza

  2. Zoology Department, Faculty of Science, Minia University, Mina, Egypt

    Hossam Abd Rabou Ebaid & Ashraf Mohamed Mashaly

  3. Chemistry Department, College of Science, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia

    Mohamed Hassan El-Newehy

  4. Chemistry Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt

    Mohamed Hassan El-Newehy

  5. Faculty of Agriculture, Saba Basha, Alexandria University, Alexandria, Egypt

    Ahmed AbdelFattah Mahmoud Abdel-Megeed

  6. Textile Research Division, National Research Center, Dokki, Cairo, Egypt

    Essam Sayed Abdel-Halim

  7. Facultad de Medicina Veterinaria y Zootecnia, Universidad Autónoma del Estado de México, Toluca, Mexico

    Abdelfattah Zeidan Mohamed Salem

Authors
  1. Hossam Abd Rabou Ebaid
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  2. Ahmed Abdel-Mageed
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  4. Iftekhar Hassan
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  5. Ahmed Mostafa Rady
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  6. Mohamed Hassan El-Newehy
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  7. Ashraf Mohamed Mashaly
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  8. Ahmed AbdelFattah Mahmoud Abdel-Megeed
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  9. Ibrahim Alhazza
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  10. Essam Sayed Abdel-Halim
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  11. Abdelfattah Zeidan Mohamed Salem
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Corresponding authors

Correspondence to Hossam Abd Rabou Ebaid or Abdelfattah Zeidan Mohamed Salem.

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Responsible Editor: Mohamed M. Abdel-Daim

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Statement of novelty

Using the electrospun nanofibers containing biosurfactant can be used to clean oil spills up and protect the environmental biology is a new approach and has a novelty in this field of waste environment. The electrospun nanofibers used in present study containing biosurfactant based on poly(ethylene oxide) (PEO-1, PEO-5) and poly(vinyl alcohol) (PVA-1, PVA-5) were prepared as cleaning materials for oil spills. The prepared nanofibers were tested on organism prior to their usage at commercial level to avoid any environmental as well as animal hazards.

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Ebaid, H.A.R., Abdel-Mageed, A., Al-Tamimi, J.H. et al. Biosurfactant electrospun nanofibers exhibit minimal side effects on the structure and function of the liver tissue in male rat model. Environ Sci Pollut Res 27, 40009–40019 (2020). https://doi.org/10.1007/s11356-020-10077-8

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