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Enantioselective fate of mandipropamid in grape and during processing of grape wine

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Abstract

Enantioselective monitoring of chiral fungicide mandipropamid enantiomers were carried out in grapes and wine-making process. The enantiomers of mandipropamid were separated on a Lux Cellulose-2 column and determined by ultra-high-performance liquid chromatography coupled with tandem mass spectrometry (UHPLC–MS/MS). The processing procedure included washing, fermentation, and clarification. Significant enantioselectivity was observed in grape under field conditions and during wine-making processing. The half-lives of R-mandipropamid and S-mandipropamid were 5.63 days and 7.79 days under field conditions 43.3 h and 69.3 h during wine-making processing, respectively. The EF values ranged from 0.498 to 0.283 in grape under field conditions, and the EF values were from 0.458 (0 h) to 0.362 (312 h) during the whole fermentation process. The results indicated that R-mandipropamid degraded faster than S-mandipropamid in grape under field conditions and during the fermentation process. The processing factors (PFs) were less than 1 for each procedure, and the PF ranged from 0.005 to 0.025 in the overall process, which indicated that the wine-making process can reduce mandipropamid residue in grape wine. The results of this study could help facilitate more accurate risk assessments of mandipropamid in table grapes and during wine-making process.

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Funding

This work was supported by Agricultural Science and Technology Innovation Program of CAAS (CAAS- ZDRW202011) and the National Program for Quality and Safety Risk Assessment of Agricultural Products of China (GJFP2019011).

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Authors and Affiliations

  1. Research Institute of Pomology, Chinese Academy of Agricultural Sciences, Xingcheng, 125100, People’s Republic of China

    Guofeng Xu, Xiaohui Jia, Haiping Zhang, Jianyi Zhang & Jiyun Nie

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  1. Guofeng Xu
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  2. Xiaohui Jia
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  3. Haiping Zhang
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  4. Jianyi Zhang
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  5. Jiyun Nie
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Correspondence to Guofeng Xu.

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Xu, G., Jia, X., Zhang, H. et al. Enantioselective fate of mandipropamid in grape and during processing of grape wine. Environ Sci Pollut Res 27, 40148–40155 (2020). https://doi.org/10.1007/s11356-020-10061-2

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