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Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery

  • Nanotechnology, Nanopollution, Nanotoxicology and Nanomedicine (NNNN)
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Abstract

Nanotechnology is an emerging technology that deals with nanosized particles possessing crucial research roles and application. Disciplines like chemistry, biology, physics, engineering, materials science, and health sciences provide an accumulated knowledge of nanotechnology. Nonetheless, it has vast submissions precisely in biology, electronics, and medicine. Aimed at drug delivery system, nanoparticles are based on the mechanism of entrapment of the drugs or biomolecules into the interior structure of the particles; another mechanism could be that the drugs or the biomolecules can be absorbed onto the exterior surfaces of the particles. Currently, nanoparticles (NPs) are used in the delivery of drugs, proteins, genes, vaccines, polypeptides, nucleic acids, etc. In recent years, various applications of the drug delivery system via NPs have encountered an enormous position sector like pharmaceutical, medical, biological, and others. Considering the impact of NPs in drug delivery systems, this review focuses on the detailed profile of NPs, its impact on biology and medicine, and their commercialization prospects.

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Abbreviations

NPs:

nanoparticles

BBB:

blood–brain barrier

SLN:

solid lipid nanoparticles

NLC:

nanostructured lipid carrier

QDs:

quantum dots

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Funding

The author(s) received no financial support for the research, authorship, and publication of this manuscript.

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Contributions

This work was carried out in collaboration between all authors. MSU designed the study, wrote the protocol, and managed the analyses of the study. NZ, RA, and MTK prepared the draft of the manuscript. DT, BM, MSU, and MTK and revised and improved the manuscript. MSU, LA, and MMA-D reviewed the scientific contents of the manuscript. All the authors read and approved the final manuscript.

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Correspondence to Md. Sahab Uddin.

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The authors declare that they have no conflict of interest.

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Responsible editor: Philippe Garrigues

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Zahin, N., Anwar, R., Tewari, D. et al. Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery. Environ Sci Pollut Res 27, 19151–19168 (2020). https://doi.org/10.1007/s11356-019-05211-0

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  • DOI: https://doi.org/10.1007/s11356-019-05211-0

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