Environmental Science and Pollution Research

, Volume 26, Issue 9, pp 8821–8827 | Cite as

Relationship between arsenic accumulation in tissues and hematological parameters in mullet caught in Faro Lake: a preliminary study

  • Francesco FazioEmail author
  • Concetta Saoca
  • Vincenzo Ferrantelli
  • Gaetano Cammilleri
  • Gioele Capillo
  • Giuseppe Piccione
Research Article


The authors investigated the arsenic (As) accumulation in different tissues (muscle, gill, liver, stomach, and intestine) and the possible correlation between tissue concentration and hematological parameters in mullet (Mugil cephalus Linnaeus, 1758) caught in Faro Lake (Messina, Sicily, Italy). On all fish, hematological analyses of blood samples, measurement of biometric indices, and the removal of the muscles, gills, liver, stomach, and intestine for the determination of arsenic concentration were performed. A hemogram was performed to find effects of arsenic concentration in tissues on hematological variables. One-way analysis of variance showed significant differences of arsenic concentration in different tissues, with higher values in the gill. The correlation between hematological parameters and tissue arsenic concentration showed a statistical significance for red blood cell (RBC), hemoglobin concentration (Hb), and hematocrit (Hct) with the liver As concentration. Biometric indices (weight, length, and fork length) showed a significant correlation with As concentration of the muscle and liver also. Our results indicate the role of some hematological parameters as biomarkers useful to monitoring anthropogenic load of arsenic in water and sediment, because variations of these parameters represent one of the effects that arsenic exposure can have on fish.


Arsenic Bioaccumulation Blood parameters Environment Fish tissues Mugil cephalus 


Compliance with ethical standard

Conflict of interest

The authors declare that they have no conflict of interest.

Statement on welfare of animals

All experimental procedures were carried out in accordance with European legislation regarding the protection of animals used for scientific purposes (European Directive 2010/63). CISS ethical committee code 017/2017.


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Copyright information

© Springer-Verlag GmbH Germany, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Veterinary SciencesPolo Universitario Annunziata, University of MessinaMessinaItaly
  2. 2.Experimental Zooprophylactic Institute of Sicily “A. Mirri”PalermoItaly
  3. 3.Department of Chemical, Biological, Pharmaceutical and Environmental SciencesMessinaItaly

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