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Environmental Science and Pollution Research

, Volume 24, Issue 4, pp 3790–3801 | Cite as

Modulatory effects of Zn2+ ions on the toxicity of citrate- and PVP-capped gold nanoparticles towards freshwater algae, Scenedesmus obliquus

  • V. Iswarya
  • J.B. Johnson
  • Abhinav Parashar
  • Mrudula Pulimi
  • N. Chandrasekaran
  • Amitava MukherjeeEmail author
Research Article

Abstract

Gold nanoparticles (GNPs) are widely used for medical purposes, both in diagnostics as well as drug delivery, and hence are prone to release and distribution in the environment. Thus, we have explored the effects of GNPs with two distinct surface capping (citrate and PVP), and three different sizes (16, 27, and 37 nm) at 0.01-, 0.1-, and 1-mg L−1 concentrations on a predominant freshwater alga Scenedesmus obliquus in the sterile freshwater matrix. We have also investigated how an abundant metal ion from freshwater, i.e., Zn2+ ions may modulate the effects of the selected GNPs (40 nm, citrate, and PVP capped). Preliminary toxicity results revealed that gold nanoparticles were highly toxic in comparison to zinc ions alone. A significant modulation in the toxicity of Zn ions was not noticed in the presence of GNPs. In contrast, zinc ions minimized the toxicity produced by GNPs (both CIT-37 and PVP-37), despite its individual toxicity. Approximately, about 42, 33, and 25% toxicity reduction was noted at 0.05-, 0.5-, and 5-mg L−1 Zn ions, respectively, for CIT-37 GNPs, while 31% (0.05 mg L−1), 24% (0.5 mg L−1), and 9% (5 mg L−1) of toxicity reduction were noted for PVP-37 GNPs. Maximum toxicity reduction was seen at 0.05 mg L−1 of Zn ions. Abbott modeling substantiated antagonistic effects offered by Zn2+ ions on GNPs. Stability and sedimentation data revealed that the addition of zinc ions gradually induced the aggregation of NPs and in turn significantly reduced the toxicity of GNPs. Thus, the naturally existing ions like Zn2+ have an ability to modulate the toxicity of GNPs in a real-world environment scenario.

Keywords

Gold nanoparticles (GNPs) Size Surface capping Zinc ions Freshwater Scenedesmus obliquus 

Notes

Acknowledgements

We sincerely thank PSG-IAS, Coimbatore, TN, India, for the TEM analysis.

Compliance with ethical standards

The authors declare that they have no conflict of interest.

Supplementary material

11356_2016_8131_MOESM1_ESM.docx (68 kb)
ESM 1 (DOCX 68 kb)

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Copyright information

© Springer-Verlag Berlin Heidelberg 2016

Authors and Affiliations

  1. 1.Centre for NanobiotechnologyVIT UniversityVelloreIndia

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