Skip to main content
SpringerLink
Log in

Anticoccidial effect of mananoligosacharide against experimentally induced coccidiosis in broiler

  • Research Article
  • Published:
Environmental Science and Pollution Research Aims and scope Submit manuscript

Abstract

The aim of this study was to find the effect of mananoligosacharide (MOS) in comparison with amprolium hydrochloride on performance and integrity of gut in experimentally induced coccidiosis in broiler. A total of 300, day-old male broiler chickens (Ross 308) was randomly allocated to four treatments. Each group was further divided into five replicates of 15 birds each. Group A was kept as control; group B was contaminated with Eimeria tenella, while groups C and D were infected with E. tenella and treated with MOS (0.8 g/kg feed) and anticoccidial drug, amprolium hydrochloride (12 g/100 l water), respectively. The results showed that weight gain, feed intake, and feed conversion ratio (FCR) were significantly higher (P < 0.05) in infected + MOS-treated group compared to the other groups. The result of oocyte per gram (OPG) was significantly higher (P < 0.05) in the group infected with coccidiosis during 5th, 7th, 10th, and 12th day post infection (dpi). Furthermore, the OPG was significantly lower (P < 0.05) in infected groups treated with MOS and amprolium at the studied periods (5, 7, and 10 dpi). At 12 dpi, the infected group treated with MOS showed significantly lower OPG compared to the other groups suggesting the effectiveness of MOS in comparison to amprolium. The result of pinpoint hemorrhages, thickness of cecal wall, bloody fecal contents, and mucoid contents in the cecum were significant highly (P < 0.05) in birds fed with infected oocytes. It was also noted that the differences were not significant in these parameters between amprolium and MOS-treated birds showing the effectiveness of the prebiotic agent. It was concluded from the results of the present study that MOS improved growth performance and reversed the lesions of E. tenella.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

Explore related subjects

Discover the latest articles, news and stories from top researchers in related subjects.

References

  • Allen PC, Fetterer RH (2002) Recent advances in biology and immunobiology of Eimeria species and in diagnosis and control of infection with these coccidian parasites of poultry. Clin Micro Rev 15:58–65

    Article  CAS  Google Scholar 

  • Baurhoo B, Phillip L, Ruiz-Feria CA (2007) Effects of purified lignin and mannanoligosaccharides on intestinal integrity and microbial populations in the ceca and litter of broiler chickens. Poult Sci 86:1070–1078

    Article  CAS  Google Scholar 

  • Bezkorovainy A (2001) Probiotics: determinants of survival and growth in the gut. Am J Clin Nutr 73(suppl):399–405

    Google Scholar 

  • Bozkurt M, Kucukyılmaz K, Catlı AU, Cınar M (2009) The effect of single or combined dietary supplementation of prebiotics, organic acid and probiotics on performance and slaughter characteristics of broilers. South Afr J Anim Sci 39(3):197–205

    Google Scholar 

  • Brouns F, Kettlitz B, Arrigoni E (2002) Resistant starch and “the butyrate revolution”. Trends Food Sci Technol 3:251–261

    Article  Google Scholar 

  • Chapman HD (1994) Sensitivity of field isolates of Eimeria to monensin following the use of coccidiosis vaccine in broiler chickens. Poult Sci 73:476–478

    Article  CAS  Google Scholar 

  • Chapman HD (1997) Biochemical, genetic and applied aspects of drug resistance in Eimeria parasite of the fowl. Avian Pathol 26:221–244

    Article  CAS  Google Scholar 

  • Chapman HD (1998) Evaluation of the efficacy of anticoccidial drugs against Eimeria species in the fowl. Int J Parasitol 28:1141–1144

    Article  CAS  Google Scholar 

  • Chapman HD (1999) The development of immunity to Eimeria species in broilers given anti coccidal drugs. Avian Pathol 28(2):155–162

    Article  CAS  Google Scholar 

  • Chapman HD (2005) Perspectives for the control of coccidiosis in poultry by chemotherapy and vaccination. Proceedings of the IXth International Coccidiosis Conference, Foz de Iguassu, Parana, Brazil. Apinco Foundation of Poultry Science and Technology, Campinas, São Paulo, Brazil, pp 99–103

  • Chio KH, Namkung H, Paik IK (1994) Effects of dietary fructolligosaccharides on the suppression of intestinal colonization of Salmonella typhimurium in broiler chickens. Korean J Anim Sci 36:271–284

    Google Scholar 

  • Crittenden RG, Playne MJ (1996) Production, properties and applications of food-grade oligosaccharides. Trends Food Sci Technol 7:353–360

    Article  CAS  Google Scholar 

  • Cummings JH, Macfarlane GT (2002) Gastrointestinal effects of prebiotics. Br J Nutr 87:145–151

    Article  Google Scholar 

  • Dzierszinski FS, Hunter CA (2008) Advances in the use of genetically engineered parasites to study immunity to Toxoplasma gondii. Parasite Immunol 30:235–244

    Article  CAS  Google Scholar 

  • Elmusharaf MA, Beynen AC (2007) Coccidiosis in poultry with emphasis on alternative anticoccidial treatments. Annals of the world association on animal pathology. Ann World Assoc Anim Pathol (AWAAP) 5:13–32

  • Elmusharaf MA, Bautista V, Nollet L, Beynen AC (2006) Effect of a mannanoligosaccharide preparation on Eimeria tenella infection in broiler chickens. Int J Poult Sci 5:583–588

    Article  Google Scholar 

  • Ferket PR, Parks CW, Grims JL (2002) Benefits of dietary antibiotic and mannanoligosaccharide supplementation for poultry. In: Proc. Multi-State Poult. Feeding and Nutr. Conf., Indianapolis, IN. May 14-16.

  • Fernandez F, Hinton M, Van Gils B (2002) Dietary mannan-oligosaccharide and their effect on chicken caecal microflora in relation to Salmonella Enteritidis colonization. Avian Pathol 31:49–58

    Article  CAS  Google Scholar 

  • Gibson GR (1999) Dietary modulation of the human microflora using the prebiotics oligofructose and inulin. J Nutr 129:1438–1441

    Google Scholar 

  • Gibson GR, Fuller R (2000) Aspects of in vitro and vivo research approaches directed towards identifying probiotics and prebiotics for human use. J Nutr 130:391–395

    Google Scholar 

  • Gibson GR, Roberfroid MB (1995) Dietary manipulation of the human colonic microbiota: introducing the concept of prebiotics. J Nutr 125:1401–1412

    CAS  Google Scholar 

  • Gibson GR, Wang X (1994) Bifidogenic properties of different types of fructooligosaccharides. Food Microbial 11:491–498

    Article  CAS  Google Scholar 

  • Gibson GR, Beatty ER, Wang X, Cummings JH (1995) Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterol 108:975–982

    Article  CAS  Google Scholar 

  • Grizard D, Barthomeuf C (1999) Non-digestible oligosaccharides used as prebiotic agents: mode of production and beneficial effects on animal and human health. Reprod Nutr Dev 39:563–588

    Article  CAS  Google Scholar 

  • Hatemink R (1995) Non digestible oligosaccharides: healthy food for the colon. Proceedings Symposium Wageningen, 4-5 December, 1-177.

  • Hidaka H, Eida T, Takiwaza T, Tokungo T, Tashiro Y (1986) Effects of fructooligosaccharide on intestinal flora and human health. Bifid Microflora 5:37–50

    Article  Google Scholar 

  • Hodgson JN (1970) Coccidiosis oocysts counting technique for coccidiostat evaluation. Expt Parasitol 28:99–102

    Article  CAS  Google Scholar 

  • Houshmand M, Azhar K, Zulkifli I, Bejo MH, Kamyab A (2012) Effects of non-antibiotic feed additives on performance, immunity and intestinal morphology of broilers fed different levels of protein. S Afr J Anim Sci 42:22–32

    Article  CAS  Google Scholar 

  • Iji PA, Saki AA, Tivey DR (2001) Intestinal structure and function of broiler chickens on diet supplemented with a mannanoligosaccharide. J Anim Sci 81:1186–1192

    CAS  Google Scholar 

  • Koc F, Samli H, Okur A, Ozduven M, Akyurek H, Senkoylu N (2010) Effects of Saccharomyces cerevisiae and/or mannanoligosaccharide on performance, blood parameters and intestinal microbiota of broiler chicks. Bulg J Agri Sci 16(5):643–650

    Google Scholar 

  • Kulkami RR, Parreira VR, Jiang YF, Prescott JF (2010) A live oral recombinant Salmonella enteric serovar Typhimurium vaccine expressing Clostridium Perfringes antigens confers protection against necrotics enteritis in broiler chickens. Clin Vaccine Immunol 17:205–214

    Article  Google Scholar 

  • Lee DJ, Drongowski RA, Coran AG (2000) Evaluation of probiotic treatment in a neonatal animal model. Pediatr Surg Int 16:237–242

    Article  CAS  Google Scholar 

  • Lillehoj HS, Min W, Dalloul RA (2004) Recent progress on the cytokine regulation of intestinal immune responses to Eimeria. Poult Sci 83:611–623

    Article  CAS  Google Scholar 

  • Loddi MM, Nakaghi LSO, Edens F, Tucci FM, Hannas MI, Moraes VMB, Ariki J (2002) Mannan oligosaccharide and organic acids on intestinal morphology integrity of broilers evaluated by scanning electron microscopy. In: Proceedings 11th European Poult. Con. Bremen Germany, pp. 121-126.

  • Long PL, Joyner LP, Millard BJ, Norton CC (1976) A guide to laboratory techniques used in the study and diagnosis of avian coccidiosis. Folia Vet Latina 6:201–217

    CAS  Google Scholar 

  • McDougald LR (2003) Coccidiosis in diseases of poultry. 11th Ed. Iowa State Press, Blackwell Publishing Company, USA. 974-991

  • Miles RD, Boot Walla SM (1991) Direct-fed microbial in animal production—a review. J Vet Med Anim Hlth 1994 5:308–316

    Google Scholar 

  • Moemen AM, Abdel-Aziz MS (2011) Effect of mannonoligosacchrides (Biomass) on necrotic enteritis infecxtion in broiler chickens. Int J Poult Sci 9(10):685–690

    Google Scholar 

  • Mohamed MA, Hassan HMA, El-Barkouky EMA (2008) Effect of mannan oligosaccharide on performance and carcass characteristics of broiler chicks. J Agric Soc Sci 4:13–17

    Google Scholar 

  • NRC (1994) Nutrient requirements of poultry, 9th edn. Natl. Acad. Press, Washington, DC

    Google Scholar 

  • Oyofo BA, Deloach JR, Corrier DE, Norman JO, Ziprin RL, Mollenhauser HH (1989) Effects of carbohydrates on Salmonella typhimurium colonisation in broiler chickens. Avian Dis 33:531–534

    Article  CAS  Google Scholar 

  • Pelicano ERL, de Souza PA, de Souza HBA, Leonel FR, Zeola NMBL, Boiago MM (2004) Productive traits of broiler chickens fed diets containing different growth promoters. Rev Bras Cienc Avicola 6:177–182

    Google Scholar 

  • Peuranen S, Kocher A, Dawson KA (2006) Yeast cell preparations prevent the attachment of enteropathogenic Escherichia coli on broiler gut mucus. Reprod Nutr Dev 46:S111

    Google Scholar 

  • Ruff MD, Danforth HD (1966) Resistance of coccidia to medications. Pages 427-430 in Proc. XX World’s Poult. Congr. vol. 11.

  • SAS (1998) User’s Guide, Statistics. SAS Institute, Cary, NC.

  • Sonmez C, Eren M (1999) Effect of supplementation of zinc bacitracin, mannanoligosaccharide, and probiotics into the broiler feed on morphology of the small intestine. Vet Fac Dergist Uludag Univ 18:125–138

    Google Scholar 

  • Spring P, Wenk C, Dawson KA, Newman KE (2000) The effects of dietary mannanoligosaccharides on cecal parameters and the concentrations of enteric bacteria in the ceca of Salmonella-challenged broiler chicks. Poult Sci 79:205–211

    Article  CAS  Google Scholar 

  • Steel RGD, Torrie JH (1981) Principles and procedures of statistics. McGraw Hill Book.Co.Inc. New York.

  • Sun X, McElroy A, Webb KE, Sefton AE, Novak C (2005) Broiler performance and intestinal alterations when fed drug-free diets. Poult Sci 84:1294–1302

    Article  CAS  Google Scholar 

  • Taherpour K, Moravej H, Taheri HR, Shivazad M (2012) Effect of dietary inclusion of probiotic, prebiotic and butyric acid glycerides on resistance against coccidiosis in broiler chickens. J Poult Sci 49(1):57–61

    Article  CAS  Google Scholar 

  • Tanweer AJ, Chand N, Saddique U, Bailey CA, Khan RU (2014) Antiparasitic effect of wild rue (Peganum harmala L.) against experimentally induced coccidiosis in broiler chicks. Parasitol Res 113:2951–2960

    Article  Google Scholar 

  • Thong Song B, Kalandakonond-Thongsong S, Chavanaikul V (2008) Effects of the addition of probiotics containing both bacteria and yeast or an antibiotics on performance parameters, mortality rate and antibiotics residue in broilers. Thai J Vet Med 38(1):17–26

    Google Scholar 

  • Williams RB (1995) Epidemiological studies of coccidiosis in the domestic fowl (Gallus gallus): IV. Reciprocity between the immune status of floor-reared chickens and their excretion of oocysts. Appl Parasitol 36:90–298

    CAS  Google Scholar 

  • Xu ZR, Hu CH, Xia MS, Zhan XA, Wang MQ (2003) Effects of dietary fructo oligosaccharide on digestive enzyme activities, intestinal microflora and morphology of male broilers. Poult Sci 82:1030–1036

    Article  CAS  Google Scholar 

  • Yang Y, Iji PA, Kocher A, Mikkelsen LL, Choct M (2007) Effects of mannanoligosaccharide on growth performance, the development of gut microflora, and gut function of broiler chickens raised on new litter. J Appl Poult Res 16(2):280–288

    Article  Google Scholar 

  • Yang Y, Iji PA, Choct M (2009) Dietary modulation of gut microflora in broiler chickens: a review of the role of six kinds of alternatives to in-feed antibiotics. Wrld’s Poult Sci J 65:97–114

    Article  Google Scholar 

  • Zikic D, Peric L, Uscebrka G, Stojanovic S, Milic D, Nollet L (2008) Effect of prebiotics in broiler breeder and broiler diets on performance and jejunum morphology of broiler chickens. 1st Mediterranean Summit of WPSA, Book of Proceedings, Porto Carras, Greece, 879-882.

Download references

Acknowledgment

The authors would like to extend their sincere appreciation to the Deanship of Scientific Research at King Saud University for its funding of this research through Research Group Project no. RGP-VPP-273.

Author information

Authors and Affiliations

  1. Faculty of Animal Husbandry and Veterinary Sciences, The University of Agriculture, Peshawar, Pakistan

    Naila Chand, Hassan Faheem, Rifat Ullah Khan & Muhammad Subhan Qureshi

  2. Department of Animal Production, College of Food and Agriculture Sciences, King Saud University, P.O. Box 2460, Riyadh, 11451, Saudi Arabia

    Rifat Ullah Khan, Ibrahim A. Alhidary & Alaeldein M. Abudabos

Authors
  1. Naila Chand
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Hassan Faheem
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Rifat Ullah Khan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Muhammad Subhan Qureshi
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Ibrahim A. Alhidary
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Alaeldein M. Abudabos
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rifat Ullah Khan.

Additional information

Responsible editor: Philippe Garrigues

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chand, N., Faheem, H., Khan, R.U. et al. Anticoccidial effect of mananoligosacharide against experimentally induced coccidiosis in broiler. Environ Sci Pollut Res 23, 14414–14421 (2016). https://doi.org/10.1007/s11356-016-6600-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11356-016-6600-x

Keywords

Search

Navigation