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Spread of extended-spectrum beta-lactamase-producing Escherichia coli from a swine farm to the receiving river

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Abstract

The dissemination of drug-resistant bacteria into different environments has posed a grave threat to public health, but data on the spread of extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) from animal farms to the receiving river are limited. Here, 57 ESBL-producing E. coli isolated from a pig farm and the receiving river were analyzed in terms of drug resistance, ESBL genes, and enterobacterial repetitive intergenic consensus (ERIC). The results showed that ESBL-producing E. coli from swine feces and downstream water of the pig farm outfall overlapped substantially in drug resistance and ESBL genes. Additionally, six ESBL-producing E. coli from the downstream water exhibited 100 % genetic similarity with strains from the swine feces. In conclusion, effluents of animal farms are a likely contributor to the presence of ESBL-producing E. coli in aquatic environments.

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Acknowledgments

This study was supported by Shandong Natural Grants (ZR2011CL013 and ZR2013CM030), Taishan Medical University Grant (2013GCC07), and Natural Science Foundations of China (81172791 and 81273212).

Ethical statement

This study was approved by Ethics Committee of Taishan Medical University.

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Authors and Affiliations

  1. College of Basic Medicine, Taishan Medical University, Taian, 271000, China

    Song Li & Wengang Song

  2. College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030800, China

    Yufa Zhou

  3. Disease Controlling Center, Veterinary Bureau of Daiyue, Taian, 271000, China

    Yufa Zhou

  4. College of Life Sciences, Taishan Medical University, Changcheng Road 619, Taian, 271000, China

    Yujing Tang, Yanxia Gao & Zengmin Miao

Authors
  1. Song Li
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  2. Wengang Song
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  3. Yufa Zhou
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  4. Yujing Tang
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  5. Yanxia Gao
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  6. Zengmin Miao
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Corresponding author

Correspondence to Zengmin Miao.

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Responsible editor: Robert Duran

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Li, S., Song, W., Zhou, Y. et al. Spread of extended-spectrum beta-lactamase-producing Escherichia coli from a swine farm to the receiving river. Environ Sci Pollut Res 22, 13033–13037 (2015). https://doi.org/10.1007/s11356-015-4575-7

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  • DOI: https://doi.org/10.1007/s11356-015-4575-7

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