Advertisement

Environmental Science and Pollution Research

, Volume 22, Issue 8, pp 6381–6386 | Cite as

Arsenic, heavy metals, phthalates, pesticides, hydrocarbons and polyfluorinated compounds but not parabens or phenols are associated with adult remembering condition: US NHANES, 2011–2012

  • Ivy ShiueEmail author
Short Research and Discussion Article

Abstract

Links between environmental chemicals and human health have emerged, but the effects on cognition were less studied. Therefore, it was aimed to study the relationships of different sets of environmental chemicals and the remembering condition in a national and population-based study in recent years. Data was retrieved from the US National Health and Nutrition Examination Surveys, 2011–2012, including demographics, blood pressure readings, serum measurements, lifestyle factors, self-reported remembering condition and urinary environmental chemical concentrations. Analyses included Chi-square test, t test and survey-weighted logistic and multi-nominal regression models. Among the elderly aged 60–80 (n = 1791), 320 (17.9 %) had difficulties in thinking or remembering. People who had difficulties in thinking or remembering had higher levels of urinary heavy metals, phthalates, pesticides and hydrocarbon concentrations but lower levels of urinary arsenic and polyfluorinated compound concentrations. During the recent past week, 146 people (8.2 %) had trouble remembering for more than three times while 619 people (35.2 %) had that for one to three times. These people had higher levels of urinary heavy metals, phthalates, pesticides and hydrocarbon concentrations but lower levels of urinary polyfluorinated compound concentrations. There were no associations with urinary bisphenols, parabens, perchlorate, nitrate or thiocyanate concentrations. This is the first time observing statistically significant risk associations of urinary heavy metals, phthalates, pesticides and hydrocarbon concentrations and the remembering condition specifically in the elderly, although the causality cannot be established. Elimination of such environmental chemicals in humans might need to be considered in future health policy and intervention programs.

Keywords

Chemicals Environmental health Risk factor Cognition Population attributable risk Memory 

Notes

Acknowledgments

IS is supported by the Global Platform for Research Leaders scheme.

Conflict of interest

None.

References

  1. Berent S, Giordani B, Albers JW, Garabrant DH, Cohen SS, Garrison RP, Richardson RJ (2014) Effects of occupational exposure to chlorpyrifos on neuropsychological function: a prospective longitudinal study. Neurotoxicology 41:44–53CrossRefGoogle Scholar
  2. Builee TL, Hatherill JR (2004) The role of polyhalogenated aromatic hydrocarbons on thyroid hormone disruption and cognitive function: a review. Drug Chem Toxicol 27:405–424CrossRefGoogle Scholar
  3. Centres for Disease Control and Prevention (CDC) (2012) National Centre for Health Statistics (NCHS) National Health and Nutrition Examination Survey Data. Hyattsville, MD: US Department of Health and Human Services, Centres for Disease Control and Prevention. Available from http://www.cdc.gov/nchs/nhanes.htm
  4. Chen NN, Luo DJ, Yao XQ, Yu C, Wang Y, Wang Q, Wang JZ, Liu GP (2012) Pesticides induce spatial memory deficits with synaptic impairments and an imbalanced tau phosphorylation in rats. J Alzheimers Dis 30:585–594Google Scholar
  5. Shiue I (2013a) Urine phthalate concentrations are higher in people with stroke: United States National Health and Nutrition Examination Surveys (NHANES), 2001–2004. Eur J Neurol 20:728–731CrossRefGoogle Scholar
  6. Shiue I (2013b) Association of urinary arsenic, heavy metal, and phthalate concentrations with food allergy in adults: National Health and Nutrition Examination Survey, 2005–2006. Ann Allergy Asthma Immunol 111:421–423CrossRefGoogle Scholar
  7. Shiue I (2013c) Urinary environmental chemical concentrations and vitamin D are associated with vision, hearing, and balance disorders in the elderly. Environ Int 53:41–46CrossRefGoogle Scholar
  8. Shiue I (2014a) Urinary thiocyanate concentrations are associated with adult cancer and lung problems: US NHANES, 2009–2012. Environ Sci Pollut Res Int. doi: 10.1007/s11356-014-3777-8 Google Scholar
  9. Shiue I (2014b) Higher urinary heavy metal, phthalate, and arsenic but not parabens concentrations in people with high blood pressure, US NHANES, 2011–2012. Int J Environ Res Public Health 11:5989–5899CrossRefGoogle Scholar
  10. Stallones L, Beseler C (2002) Pesticide illness, farm practices, and neurological symptoms among farm residents in Colorado. Environ Res 90:89–97CrossRefGoogle Scholar
  11. Suarez-Lopez JR, Himes JH, Jacobs DR Jr, Alexander BH, Gunnar MR (2013) Acetylcholinesterase activity and neurodevelopment in boys and girls. Pediatrics 132:e1649–e1658CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.School of Energy, Geoscience, Infrastructure and SocietyHeriot-Watt UniversityEdinburghUK
  2. 2.Owens Institute for Behavioral ResearchUniversity of GeorgiaAthensUSA

Personalised recommendations