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Removal of non-steroidal anti-inflammatory drugs ibuprofen and ketoprofen from water by emulsion liquid membrane

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Abstract

In this work, the removal of the worldwide non-steroidal anti-inflammatory drugs ibuprofen (IBP) and ketoprofen (KTP) by emulsion liquid membrane (ELM) was carried out. An ELM system is made up of hexane as diluent, Span 80 as the surfactant and sodium carbonate as the inner aqueous solution. Effect of experimental conditions that affect the extraction of IBP such as surfactant concentration, emulsification time, sulfuric acid concentration in external phase, acid type in external phase, internal phase concentration, type of internal phase, stirring speed, volume ratio of internal phase to membrane phase, treatment ratio, IBP initial concentration, diluent type and salt was investigated. The obtained results showed that by appropriate selection of the operational parameters, it was possible to extract nearly all of IBP molecules from the feed solution even in the presence of high concentration of salt. Under optimum operating conditions, the efficiencies of IBP removal from distilled water (99.3 %), natural mineral water (97.3 %) and sea water (94.0 %) were comparable, which shows that the ELM treatment process represents a very interesting advanced separation process for the removal of IBP from complex matrices such as natural and sea waters. Under the optimized experimental conditions, approximately 97.4 % KTP was removed in less than 20 min of contact time.

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Acknowledgments

The financial support by the General Directorate for Scientific Research and Technological Development (PNR project no. 4/D/25) and the Ministry of Higher Education and Scientific Research of Algeria (projects No. J0101120090018 and J0101120120098) is greatly acknowledged.

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Authors and Affiliations

  1. Laboratory of Environmental Engineering, Department of Process Engineering, Faculty of Engineering, Badji Mokhtar-Annaba University, P.O. Box 12, 23000, Annaba, Algeria

    Attef Dâas & Oualid Hamdaoui

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  1. Attef Dâas
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  2. Oualid Hamdaoui
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Correspondence to Oualid Hamdaoui.

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Responsible editor: Bingcai Pan

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Dâas, A., Hamdaoui, O. Removal of non-steroidal anti-inflammatory drugs ibuprofen and ketoprofen from water by emulsion liquid membrane. Environ Sci Pollut Res 21, 2154–2164 (2014). https://doi.org/10.1007/s11356-013-2140-9

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  • DOI: https://doi.org/10.1007/s11356-013-2140-9

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