Topical sevoflurane: analgesic management in a marathon runner with plantar fasciitis
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We present a case of a Caucasian adult marathon runner with a 3-month history of severe unilateral pain in the left heel. Magnetic resonance imaging showed an enthesitis of the plantar fascia. His baseline VAS score was 1/10, but this increased to 7/10 post-exercise, and not alleviated by non-invasive treatments. Initially, patient-directed treatments consisting of rest, ice massage, oral analgesics, diclofenac gel, and stretching techniques for several weeks. His primary goal was to return to running marathons without symptoms. A sevoflurane 0.5% gel preparation was topically applied in the affected area at doses of 0.25–0.5 mL/cm2, resulting in a pain-free region shortly after the application (VAS score 0/10), thus enabling normal physical activity for up to 60 min, without further damage to the plantar fascia. The novel use of topical sevoflurane gel in the management of PF pain is reported and discussed herein.
KeywordsPlantar fasciitis Heel pain Painful heel syndrome Topical drug Sevoflurane
Compliance with ethical standards
Conflict of interest
The authors have declared no conflict of interest.
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.
All of the subjects provided written consent to participate in the study, after the study procedure and methods were explained to them.
The results of the study are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation, and were included in work submitted by Mr. F. Dámaso Fernández-Ginés as part of requirements of the doctorate program in pharmacy at the University of Granada, Granada, Spain.
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