The rise of lactic acid, from a pharmacist’s laboratory to entry into the central nervous system

  • Maria Cristina Petralia
  • Valentina Perciavalle
  • Maria Sofia Basile
  • Giovanna Alagona
  • Aldo Monaca
  • Andrea Buscemi
  • Marinella Coco
Short Communication
  • 9 Downloads

Abstract

Brief historical review of lactic acid: since its discovery in the laboratory of Scheele, passing the role in muscle and systemically observed by scientists Friherre Jons Jakob Berzelius, Araki, Meyerhof, Margaria, Cori until joining and role in the Nervous System Central by scientists Davis, Brooks, Connet, Richardson, Donovan, Magistretti and Pellerin.

Keywords

Lactate Central nervous system History of medicine 

Notes

Compliance with ethical standards

Funding

Authors state that they have not received funding for this study.

Conflict of interest

The authors declared no conflict of interests.

Ethical approval

All procedures performed in studies involving human participants were in accordance with ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

For this type of study formal consent is not required.

References

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    Coco M (2017) The brain behaves as the muscle? Neurol Sci.  https://doi.org/10.1007/s10072-017-3014-6 Google Scholar

Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Biomedical and Biotechnological SciencesUniversity of CataniaCataniaItaly
  2. 2.Department of Educational SciencesUniversity of CataniaCataniaItaly
  3. 3.Department of NeurologyCannizzaro Hospital, CataniaCataniaItaly
  4. 4.Polytechnic of the SeaCataniaItaly
  5. 5.Horus Cooperative SocialRagusaItaly

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